INVESTIGATING THE PROTECTIVE PROPERTIES OF MILK PHOSPHOLIPIDS AGAINST ULTRAVIOLET LIGHT EXPOSURE IN A SKIN EQUIVALENT MODEL.

• TR Number: 614
• Authors: Ashley Russell1, A., Laubscher2, A., Jimenez-Flores2, R., Laiho1, L.H. 1Biomedical Engineering Department, California Polytechnic State University, San Luis Obispo, CA USA 93407. 2Dairy Products Technology Center, California Polytechnic State University, San Luis Obispo, CA USA93407. Proc. of SPIE, 7569, 7569Z, (2010).
• Materials Tested: 1% milk phospholipid solution, Milk, UVB

Current research on bioactive molecules in milk has documented health advantages of bovine milk and its components. Milk Phospholipids, selected for this study, represent molecules with great potential benefit in human health and nutrition. In this study we used confocal reflectance and multiphoton microscopy to monitor changes in skin morphology upon skin exposure to ultraviolet light and evaluate the potential of milk phospholipids in preventing photodamage to skin equivalent models. The results suggest that milk phospholipids act upon skin cells in a protective manner against the effect of ultraviolet (UV) radiation. Similar results were obtained from MTT tissue viability assay and histology.