Modified Screening Methodology Evaluating the Ocular Irritation Potential Using Human Corneal Epithelium Model EpiOcular for Cosmetic and Personal-Care Products
Abstract: Evaluating ocular irritation is critical for the safety assessment of facial and eye area cosmetics. One of the most sensitive and human-relevant eye irritation test methods is an adaption of the time-to-toxicity protocol using a reconstructed human corneal epithelium model (EpiOcularTM, Mattek Corporation). Depending on the expected irritation potential (based on the product type, […]