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Tissue Models

Scalp condition improvement with botanical extracts possessing chemical and physical antioxidant activity

  • TR Number: 1074
  • Authors: Jennifer M Marsh, Lijuan Li, Sonja Knowles, Kathryn C S Locker, Kathleen Pearson, Rob Bacon, Kimberly Kozak, Tim Laughlin, James R Schwartz
  • Keywords: EpiDerm EPI-200, botanical extracts, UVB. cypridina luciferin chemiluminescence reagent, NRF-2, reactive oxygen species, ROS, Rosemary extract, Apple extract, Black tea extract, White tea extract, Ginger tea extract, Pomegranate extract, antioxidant, oxygen radical absorbance capacity ORAC, shampoo hair formulations, scalp condition
  • Materials Tested: botanical extracts,  Rosemary extract, Apple extract, Black tea extract, White tea extract, Ginger tea extract, Pomegranate extract
  • Link to Article: https://pubmed.ncbi.nlm.nih.gov/39528839/

Oxidative stress is implicated in scalp and hair health manifesting in several ways, including skin barrier, hair retention, healthy hair appearance and scalp sensation. We previously linked markers of oxidative damage to dandruff and skin barrier impairment and have linked key anti-dandruff technologies to the resolution of these issues. Here we expand the therapeutic space demonstrating many botanical extracts offer protective benefits against ROS stress via both chemical and biological antioxidant mechanisms.