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PRE-VALIDATION OF RECONSTRUCTED EPIVAGINAL TISSUE MODEL TO SCREEN IRRITATION POTENTIAL OF CHEMICALS.

Ayehunie, S., Cannon, C., LaRosa, K., Hayden, P., and Klausner, M. MatTek Corporation, Ashland, MA, USA.
Keywords

EpiVaginal, Estradiol receptor, Histology, IL-1a, IL-1b, IL-6, IL-8, Irritation, Sodium fluorescein (NaFl) leakage, Tissue viability, Trans-epithelial electrical resistance (TEER), VEC-100, VEC-100-FT, Vaginal irritation

Materials Tested

Benzalkonium chloride, Benzocaine, Miconazole nitrate, Nonoxynol 9, Polydimethylsiloxane, Providine iodide

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