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Natural Product Celastrol Destabilizes Tubulin Heterodimer and Facilitates Mitotic Cell Death Triggered by Microtubule-Targeting Anti-Cancer Drugs
- TR Number: 2044
- Authors: Hakryul Jo; Fabien Loison; Hidenori Hattori; Leslie E. Silberstein; Hongtao Yu; Hongbo R. Luo
- Institution: Dana-Farber/Harvard Cancer Center
- Link to PDF: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0010318#
- Part Number Cited: 35 mmglass bottom dish (Mattek Corp.)
- Pub Name: PLoS ONE
- Volume: 5
- Issue: 4
- Year: 2010
- Cell Line: HEK293 and HeLa cell lines
- Part No:
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- Reproducibility - eye (ocular) tissue model
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- Irritation>Eye Irritation OECD TG 492
- Skin differentiation
- Barrier repair
- Inflamed Bowel Disease
- Visible Light
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