Skip to Main Content
+1 (508) 881-6771
0
Menu Button

Genomics

501

USE OF DIFFERENTIAL DISPLAY-POLYMERASE CHAIN REACTION TO IDENTIFY GENES SELECTIVELY MODULATED BY CHEMICAL ALLERGENS IN RECONSTITUTED HUMAN EPIDERMIS.

In the screening of topical drugs, cosmetics and other chemicals for human use, it is very important, both from a safety and an economic point of view, to have biological […]
132

CYTOKINE GENE EXPRESSION IN THE Mattek EPIDERM™ CULTURES.

Human skin equivalent cultures are currently being investigated as in vitro models to predict the contact sensitization potential of chemicals. The objective of the research presented here is to evaluate […]
234

MICROARRAY ANALYSIS OF GENE EXPRESSION FOLLOWING EXPOSURE TO SKIN IRRITANTS.

Understanding of the mechanistic basis of the human skin irritation response is key to the development of relevant in vitro test systems for the predictive identification of skin irritation hazards. […]
303

GENE EXPRESSION PROFILE OF TISSUE ENGINEERED SKIN SUBJECTED TO ACUTE BARRIER DISRUPTION.

The main function of the skin is to protect the body from infection, dehydration, and other environmental insults by creating an impermeable barrier of cornified cell layers, the stratum corneum. […]
447

SYSTEMATIC IDENTIFICATION OF PROTEASES AND ANTI-PROTEASES IN DEVELOPING PRIMARY AIRWAY EPITHELIAL CELLS BY GLOBAL GENE EXPRESSION.

This study by researchers at Oxford University demonstrated that the genomics of human epithelial tissue development and differentiation can be investigated using standard global gene expression analysis techniques and Mattek’s […]
567

XENOBIOTIC METABOLIZING CAPABILITIES OF THE EPIDERM IN VITRO HUMAN SKIN EQUIVALENT.

This study by scientists at Procter and Gamble, the Institute for In Vitro Sciences (IIVS), and Mattek Corp. demonstrated that Mattek’s EpiDerm in vitro human skin tissue equivalent possesses numerous […]
387

PROTECTING THE SKIN AGAINST OZONE.

This study by researchers at Arch Personal Care Products and Bioinnovation Laboratories demonstrated that Mattek’s EpiDerm and MelanoDerm in vitro human skin tissue equivalents could be used to prove that […]
366

ANALYSIS OF GLOBAL GENE EXPRESSION PROFILE CHANGES DURING THE DIFFERENTIATION OF THE EPIDERM™ IN VITRO HUMAN SKIN EQUIVALENT.

This study by researchers at Oxford University’s Wellcome Trust Centre for Human Genetics and the Oxford Centre for Gene Function demonstrated how Mattek’s EpiDerm in vitro human skin tissue equivalent […]