Antioxidants

Scalp condition improvement with botanical extracts possessing chemical and physical antioxidant activity

Oxidative stress is implicated in scalp and hair health manifesting in several ways, including skin barrier, hair retention, healthy hair appearance and scalp sensation. We previously linked markers of oxidative damage to dandruff and skin barrier impairment and have linked key anti-dandruff technologies to the resolution of these issues. Here we expand the therapeutic space […]

Protective effects of a comprehensive topical antioxidant against ozone‑induced damage in a reconstructed human skin model

Tropospheric ozone (O3) is a source of oxidative stress. This study examined the ability of a topical antioxidant (WEL-DS) to inhibit O3-mediated damage in a human epidermal skin model. Four groups of tissues (N = 24) were compared: Group 1 (control) were untreated and unexposed; Group 2 were untreated and exposed to O3 (0.4 ppm, […]

Novel antioxidants are not toxic to normal tissues but effectively kill cancer cells

Free radicals are formed as a result of cellular processes and play a key role in predisposition to and development of numerous diseases and of premature aging. Recently, we reported the syntheses of a number of novel phenolic antioxidants for possible application in food industry. In the present study, analyses of the cellular processes and […]

INHIBITING THE EFFECTS OF OXIDATIVE STRESS VIA TOPICALLY APPLIED ANTIOXIDANT FORMULATIONS.

VISUALIZATION AND CHARACTERIZATION OF UVB-INDUCED REACTIVE OXYGEN SPECIES IN A HUMAN SKIN EQUIVALENT MODEL.

This study by researchers at Procter and Gamble, Kyoto University and Kyoto Pharmaceutical University demonstrated that Mattek’s EpiDerm in vitro 3-D human skin tissue equivalent is useful for visualizing the production of UVB-induced Reactive Oxygen Species (ROS) in real-time, and for evaluating the efficacy of topically applied anti-oxidative compounds to suppress ROS generation and attenuate […]