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August 29, 2024

Ionic liquids as a class of materials for transdermal delivery and pathogen neutralization

Biofilm-protected microbial infections in skin are a serious health risk that remains to be adequately addressed. The...

August 29, 2024

Cytotoxicity and Bioimmunological Activity of Poly(2-Isopropenyl-2- oxazoline) Conjugates with Ibuprofen Using 3D Reconstructed Tissue Models

Poly(2-isopropenyl-2-oxazoline) (PIPOx) represents a universal polymer platform with pendant 2-oxazoline groups, allowing the preparation of biomaterials for...

August 29, 2024

Evaluation of skin irritation potentials of different cosmetic products in Turkish market by reconstructed human epidermis model

Human skin is a protective barrier against the toxic effects of cosmetics. Marketing of cosmetic products with...

August 29, 2024

Mucoadhesive chitosan-poly (lactic-co-glycolic acid) nanoparticles for intranasal delivery of quetiapine – Development & characterization in physiologically relevant 3D tissue models

Quetiapine hemifumarate (QF) delivery to the CNS via conventional formulations is challenging due to poor solubility and...

August 29, 2024

Novel Organotypic Patient-Derived Primary Tumor Tissues for Oncology Drug Safety and Efficacy Studies

Organotypic, three-dimensional (3D) cancer tissue models (OCTM) have enabled investigators to develop predictive markers that can be...