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Human Tissue Models

Mattek’s lab-grown human epithelial tissues are living, metabolically active 3D tissue models that provide greater insight into clinical outcomes.

EpiAlveolar™

Product Overview

Primary Cells Media

Mattek’s decades-long expertise in cell isolation and expansion has created a large and diverse inventory of primary cells from native donor tissue. 3D-certified cells for elevated biological research.

Cultureware

Mattek Dishes have set the benchmark for cell culture and imaging excellence for nearly 40 years. Experience the optical clarity and precision of glass in a Petri dish.

Visikol Products

We offer several reagents and supporting materials that provide researchers with an unprecedented view of tissues for enhanced characterization.

News & Resources

December 11, 2015

CHARACTERIZATION OF RECONSTRUCTED SKIN MODELS.

The aim of the present study was to evaluate tissue architecture and lipid composition of commercially available...

December 11, 2015

NOTCH-1 MEDIATED SIGNALING INCREASES IKKα LEVELS – A CRITICAL DETERMINANT CONTROLLING KERATINOCYTE TERMINAL DIFFERENTIATION AND CELL SURVIVAL.

Epidermal formation depends on a balance between cell proliferation, differentiation, and death. While deletion of IKKα gene...

December 11, 2015

EXPRESSION OF CYCLOOXYGENASE IN THE EPIDERM™ HUMAN SKIN MODEL: REGULATION BY ULTRAVIOLET RADIATION AND CYTOKINES.

Cyclooxygenase-2 (COX-2) appears to play an important role in skin carcinogenesis caused by solar ultraviolet radiation (UVR):...

December 11, 2015

EVIDENCE THAT NITRIC OXIDE IS AN UPSTREAM MEDIATOR OF FASL-MEDIATED KERATINOCYTE APOPTOSIS IN TOXIC EPIDERMAL NECROLYSIS.

Toxic epidermal necrolysis (TEN or Lyell's syndrome) is a severe adverse drug reaction that results in extensive...

December 11, 2015

TERMINAL DIFFERENTIATION OF HUMAN KERATINOCYTES AND STRATUM CORNEUM FORMATION IS ASSOCIATED WITH CASPASE-14 ACTIVATION.

Programmed cell death of epidermal keratinocytes (KC) results in the formation of cornified cells, which constitute the...