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UV toxicity

879

Development of a Model for Assessment of Blue Light Activated Toxicity in EpiGingival™ and EpiGingival™-FT Tissues

Traditional phototoxicity models examine activation of test material by ultraviolet A (UVA) light. In these models, the ability of a test chemical to induce toxicity in cells or tissues after light exposure is compared to non-light exposed tissues. While UV-induced toxicity is of great concern, it is clear that lower energy light in the blue […]
795

Total Defense + Repair: A Novel Concept in Solar Protection and Skin Rejuvenation

For more than a century, solar radiation has been known to contribute Significantly to the extrinsic aging of skin. Until recently, this was almost exclusively attributed to the photodamage caused by ultraviolet (UV) light. However, a growing body of evidence now indicates that both infrared (IR) and visible light may also contribute to extrinsic skin aging. Infrared […]
595

DC DETOXDEFENSE™ STIMULATES SKIN’S OWN SOD ANTIOXIDANT PROTECTION AND DETOXIFICATION.

Objective: The objective of this experiment was to determine whether the results previously obtained DC Detoxdefense in enzymatic and cell-based assays are corroborated by modulation of gene expression in EpiDerm human skin substitute model. Methods: EpiDerm tissues were obtained from Mattek (Ashland, MA) and cultured according to the manufacturer’s instructions. The test materials – Upregulex […]