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Skin de-pigmentation

1049

Application of MelanoDerm, an Epidermal Model Containing Functioning Melanocytes for Skin Lightening Studies

Considerable interest exists in evaluating cosmetic and/or skin care pharmaceutical formulations which cause lightening of the skin. These products are utilized to cosmetically alter one’s natural skin color or to combat skin pigmentation disorders such as melasma, post-inflammatory hyperpigmentation, and other hyperpigmentation lesions. In order to aid in the development and testing of such products, […]
1039

Efficacy and tolerability of a depigmenting gel serum comprising tranexamic acid, niacinamide, 4-butylresorcinol, phytic acid, and a mixture of hydroxy acids that targets the biological processes regulating skin melanogenesis

Background: The diverse causes of hyperpigmentation and complex nature of melanogenesis make it a challenge to manage. Current approaches either fail to deliver effective pigmentation control or have undesirable safety profiles that preclude their long-term use. Aims: To evaluate the capacity of a cosmetic gel serum comprising tranexamic acid, niacinamide, 4-butylresorcinol, phytic acid, and a […]