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Microbial

822

Anthralin modulates the expression pattern of cytokeratins and antimicrobial peptides by psoriatic keratinocytes

Background: Psoriasis is an inflammatory skin disease with aberrant keratinocyte proliferation, presumably as a result of immune cell activation. Th17 cytokines like IL-17A and IL-22 are critically implicated in epidermal thickening, altered keratinocyte differentiation and production of innate factors such as antimicrobial peptides. Psoriasis treatment options include modern targeted therapies using anti-cytokine antibodies and traditional […]
480

REVERSIBLE DEFICIENCY OF ANTIMICROBIAL POLYPEPTIDES IN BACTERIAL VAGINOSIS.

This study by researchers from the University of California at Los Angeles (UCLA) demonstrated that Mattek’s EpiVaginal human vaginal ecto-cervical tissue equivalent containing dendritic cells can be used to examine the interactions between pathological alterations of vaginal flora and the composition and antimicrobial properties of vaginal fluid. Bacterial vaginosis is a common condition associated with […]