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Cosmetics

1042

Evaluation of skin irritation potentials of different cosmetic products in Turkish market by reconstructed human epidermis model

Human skin is a protective barrier against the toxic effects of cosmetics. Marketing of cosmetic products with ingredients tested on animals was prohibited in 2013. Since then, safety evaluation of […]
869

Coumestrol Down-Regulates Melanin Production in Melan-a Murine Melanocytes through Degradation of Tyrosinase

Pigmentation reflects skin darkening caused by melanin production, but excessive melanin synthesis may cause problems, such as melasma, solar lentigo, dark spots, and freckles. Considerable effort has been devoted to […]
809

Application of Mattek In Vitro Reconstructed Human Skin Models for Safety, Efficacy Screening, and Basic Preclinical Research

During the past three decades, great progress has been achieved in the development of in vitro reconstructed human epidermal (RhE) tissue models. This technology is now available via various manufacturers of […]
280

COMPARISON OF CUTANEOUS BIOAVAILABILITY OF COSMETIC PREPARATIONS CONTAINING CAFFEINE OR ALPHA-TOCOPHEROL APPLIED ON HUMAN SKIN MODELS OR HUMAN SKIN EX VIVO AT FINITE DOSES.

The use of human skin models for performing cutaneous bioavailability studies has been little investigated. For instance, only few studies have been reported on human skin models dealing with vehicle […]