Functional Characterization and Permeation Studies of Lyophilised Thiolated Chitosan Xerogels for Buccal Delivery of Insulin
Stable and mucoadhesive, lyophilised, thiolated chitosan xerogels, loaded with insulin for buccal mucosa delivery, in place of the currently used parenteral route have been developed. The xerogels were backed with impervious ethylcellulose laminate to ensure unidirectional release and also loaded with enzyme inhibitor to enhance insulin permeability across the buccal mucosa. Characterization of xerogels using […]