Applications & Services

Dermal

With multiple regulatory validations, MatTek's scientific solutions for the cosmetic, pharmaceutical, and chemical industries, ensure safe and effective product development while reducing reliance on animal testing. From skin irritation and sensitization studies to wound healing and drug delivery research, MatTek’s innovative technologies provide reliable, reproducible, and regulatory-compliant results.

Immune Cell

MatTek generates dendritic immune cells from CD34+ progenitor cells from cord blood. Utilized for microbial infection and allergenicity testing, MatTek's immune cells deliver highly predictive data on cytokine release, immune modulation, and drug-induced immune reactions, supporting the pharmaceutical, biotech, and chemical industries in developing safer and more effective therapies.

Intestinal

MatTek's 3D human intestinal tissue models assess drug absorption, toxicity, permeability, and microbiome interactions. Our scientific solutions support the pharmaceutical, nutraceutical, and food industries, enabling safer and more effective product development while providing preclinical insight into clinical outcomes.

Ocular

MatTek's 3D human corneal tissue models for accurate and ethical assessment of eye irritation, toxicity, permeability, and drug delivery. With regulatory-validated solutions from eye irritation and corrosivity testing to ophthalmic drug development and contact lens research, MatTek’s innovative ocular models deliver reliable, reproducible, and regulatory-compliant results.

Oral Mucosal

MatTek is a leader in in vitro oral mucosal testing, offering 3D human gingival and buccal tissue models to assess oral irritation, toxicity, permeability, and drug delivery. Achieve reliable, reproducible, and regulatory-compliant results with cutting-edge oral mucosal testing that advances dental treatments, drug formulations, and personal care products.

Respiratory

From inhalation exposure studies and airway irritation testing to infectious disease research and aerosolized drug screening, MatTek’s advanced models of the human airway deliver reliable, reproducible, and human-relevant results. Partner with MatTek for innovative airway toxicity testing that enhances respiratory health and therapeutic development.

Vaginal

MatTek offers advanced in vitro vaginal tissues for drug delivery, irritation, toxicity, and infection research. Providing highly predictive data for the pharmaceutical, personal care, and women's health industries, EpiVaginal enables the safe and effective development of topical treatments, lubricants, microbicides, and feminine hygiene products while reducing reliance on animal testing.

HUREL Micro Liver Services

HUREL® micro livers are self-assembling co-cultures (SACCs) of primary hepatocytes that are cryopreserved and combined with a non-parenchymal (stromal) cell line. The hepatocytes spontaneously self-assemble into colonies. This patented form of liver cell culture has been demonstrated, in peer-reviewed studies, to produce the longest-enduring, most phenotypically stable and metabolically competent of any liver tissue construct developed in the world to date.

Visikol In Vitro Services

Visikol offers a suite of validated assays utilizing 3D cell culture models, as well as traditional monolayer models, as a contract research organization. We specialize in assay endpoints useful for drug discovery and screening compounds for pharmaceutical development, including screens for compound efficacy screening and the evaluation of toxicological liabilities.

Visikol Multiplex Immunofluorescent Labeling

Visikol Image and Analysis Services

In recent decades, the increase in computing power and the development of automated microscopes and high-performance slide scanners have revolutionized the field of bioimaging. With the ability to process vast amounts of data, researchers are now able to glean new insights and drive innovation in their respective fields.

Visikol Therapeutic Areas