Reference Libraries

December 11, 2015

CONFOCAL MICROSCOPY FOR MODELING ELECTRON MICROBEAM IRRADIATION OF SKIN.

For radiation exposures employing targeted sources such as particle microbeams, the deposition of energy and dose will depend on the spatial heterogeneity of the sample. Although cell structural variations are rela- tively minor for two-dimensional cell cultures, they can vary... Read More

December 11, 2015

THE USE OF STANDARDIZED HUMAN SKIN MODELS FOR CUTANEOUS PHARMACOTOXICOLOGY STUDIES.

Reconstructed skin and epidermis models are finding increasingly numerous applications in cosmetology and dermatology. In particular, they are currently employed to assess the tolerability and efficacy of raw materials and formulations, in conditions approaching those of normal use. Importantly, the... Read More

December 11, 2015

FORMULATION OPTIMIZATION, SKIN IRRITATION, AND EFFICACY CHARACTERIZATION OF A NOVEL SKIN-LIGHTENING AGENT.

Background: Skin-lightening preparations are used by people all over the world for a diverse range of dermatologic indications. The gold standard treatment for skin lightening is with hydroquinone but has been controversial because of the presence of several side effects.... Read More

December 11, 2015

DEVELOPMENT OF IN VITRO METHODS FOR EVALUATING THE EPIDERMAL AND DERMAL EFFECTS OF ALPHA HYDROXY AND AMIDES.

Several in vitro methods for their ability to replicate in vivo effects of selected alpha hydroxy acids and amides on the epidermis and dermis have been investigated. Cytotoxicity, prostaglandin release, morphology and histology on single cells and on tissue models... Read More

December 11, 2015

PROGRAM TO REDUCE ANIMAL TESTING FOR EPA REGISTRATIONS OF ANTIMICROBIAL PRODUCTS.

This study by scientists at Proctor & Gamble, S.C. Johnson, the Institute for In Vitro Sciences (IIVS) and The Accord Group, in conjunction with the US EPA, documented how MatTek’s EpiDerm in vitro human skin tissue equivalent and EpiOcular in... Read More

Reference Libraries

CONFOCAL MICROSCOPY FOR MODELING ELECTRON MICROBEAM IRRADIATION OF SKIN.

THE USE OF STANDARDIZED HUMAN SKIN MODELS FOR CUTANEOUS PHARMACOTOXICOLOGY STUDIES.

FORMULATION OPTIMIZATION, SKIN IRRITATION, AND EFFICACY CHARACTERIZATION OF A NOVEL SKIN-LIGHTENING AGENT.

DEVELOPMENT OF IN VITRO METHODS FOR EVALUATING THE EPIDERMAL AND DERMAL EFFECTS OF ALPHA HYDROXY AND AMIDES.

PROGRAM TO REDUCE ANIMAL TESTING FOR EPA REGISTRATIONS OF ANTIMICROBIAL PRODUCTS.

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