Reference Libraries

December 11, 2015

A LOTION CONTAINING UNDECYLENOYL PHENYLALANINE AND ERGOTHIONEINE REDUCES MELANIN LEVELS WITHOUT AFFECTING TISSUE VIABILITY IN ARTIFICIAL SKIN CONSTRUCTS.

This study by scientists at AGI Dermatics demonstrated that MatTek’s MelanoDerm in vitro human skin tissue equivalent can be used to evaluate the depigmentation (lightening) effects of skin lotion additives caused by a reduction in melanin production without tissue/cell toxicity.... Read More

December 11, 2015

INHIBITORY EFFECTS OF A NOVEL ASCORBIC DERIVATIVE, DISODIUM ISOSTEARYL 2-O-L-ASCORBYL PHOSPHATE ON MELANOGENESIS.

This study by researchers at Toyo Beauty Co., Ltd., Jichi Medical University, and Kinki University (Japan) demonstrated how MatTek’s MelanoDerm 3-D human skin tissue equivalent containing both keratinocytes and melanocytes can be used as an in vitro test of the... Read More

December 11, 2015

INHIBITION OF MELANOSOME TRANSFER RESULTS IN SKIN LIGHTENING.

The chemical basis of melanogenesis is well documented, but the mechanism of melanosome transfer and the regulation of pigmentation by keratinocyte-melanocyte interactions are not well understood. Therefore we examined the effects of serine protease inhibitors on skin pigmentation and found... Read More

December 11, 2015

A NATURAL NEW ACTIVE WHITENING MOLECULE.

Tyrosinase has long been commonly considered as the sole enzyme involved in melanogenesis and has served as target to develop whitening agents. But, over the past decade, it has become well accepted that melanins pathways involve many other enzymes such... Read More

December 11, 2015

USE OF MELANODERM™, AN EPIDERMAL MODEL CONTAINING FUNCTIONAL MELANOCYTES TO STUDY MODULATORS OF SKIN PIGMENTATION.

There is considerable interest in developing both cosmetic and pharma-ceutical formulations which cause darkening or lightening of the skin. These products are utilized to cosmetically alter one’s natural skin color, to provide natural protection from UV irradiation (by increasing melanin... Read More

Reference Libraries

A LOTION CONTAINING UNDECYLENOYL PHENYLALANINE AND ERGOTHIONEINE REDUCES MELANIN LEVELS WITHOUT AFFECTING TISSUE VIABILITY IN ARTIFICIAL SKIN CONSTRUCTS.

INHIBITORY EFFECTS OF A NOVEL ASCORBIC DERIVATIVE, DISODIUM ISOSTEARYL 2-O-L-ASCORBYL PHOSPHATE ON MELANOGENESIS.

INHIBITION OF MELANOSOME TRANSFER RESULTS IN SKIN LIGHTENING.

A NATURAL NEW ACTIVE WHITENING MOLECULE.

USE OF MELANODERM™, AN EPIDERMAL MODEL CONTAINING FUNCTIONAL MELANOCYTES TO STUDY MODULATORS OF SKIN PIGMENTATION.

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