Reference Libraries

EpiDerm™ is a model of the human epidermis grown from normal human epidermal keratinocytes (foreskin-derived) seeded onto Millicell® CM (Millipore Corp., Bedford, MA) cell culture inserts. The inserts are placed at the air/culture medium interface allowing the cells to differentiate... Read More

The in vitro evaluation of the dermal irritation potential of volatile or water insoluble petroleum products has generally proved difficult. Scientists at ARCO and Microbiological Associates utilized three human skin constructs (Living Skin Equivalent [LSE], Organogenesis, Inc., Cambridge, MA; Skin2... Read More

Scientists at Procter & Gamble Co. previously reported the development of a battery of endpoints in human skin cultures that correlate with human skin irritation responses to selected prototype surfactants. The purpose of the present study was to directly compare... Read More

A model of the human epidermis, EpiDerm™, cultured from neonatal fore-skin-derived normal human epidermal keratinocytes (NHEK) was introduced by MatTek Corporation in April 1993. Using highly controlled tissue culture techniques, weekly batches of EpiDerm are produced and shipped domestically and... Read More