Reference Libraries

December 11, 2015

1-(2,4-DIHYDROXYPHENYL)-3-(2,4-DIMETHOXY-3-METHYL-PHENYL)PROPANE, A NOVEL TYROSINASE INHIBITOR WITH STRONG DEPIGMENTING EFFECTS.

This study by researchers at Unigen Pharmaceuticals and Texas Christian University demonstrated that MatTek’s MelanoDerm in vitro human skin tissue equivalent is an excellent in vitro model for studying the efficacy and safety of novel human skin lightening compounds. A... Read More

December 11, 2015

EVALUATION OF EPIDERM™ AS A MODEL TO STUDY IRRITATION AFTER EXPOSURE TO VARIOUS ALIPHATIC HYDROCARBONS FOUND IN JET FUELS.

This study by scientists at Florida A&M University College of Pharmacy, Auburn University Harrison School of Pharmacy, and MatTek Corp. demonstrated that MatTek’s EpiDerm in vitro human skin tissue equivalent is an excellent in vitro alternative to animal testing for... Read More

December 11, 2015

DEVELOPMENT OF AN IN VITRO MODEL FOR THE PREDICTION OF SKIN IRRITATION POTENTIAL.

Cytokines important to the inflammatory cascade were measured both at the level of transcription and secreted protein, from skin equivalents topically exposed to a panel of relevant consumer products. The response of a full thickness model, consisting of both keratinocytes... Read More

December 11, 2015

Skin irritation and potential efficacy of a novel compound for localized treatment of psoriasis

Psoriasis is a chronic condition characterized by formation of white scaly patches on the skin. Current treatment options include topical glucocorticoids which have several side effects. Pentaerythritol tetrakis (3,5-di-tert-butyl-4-hydroxyhydrocinnamate) (PTTC) is a cinnamate tetraester which may be used as a... Read More

December 11, 2015

AN IN VITRO METHOD FOR SCREENING ANTI-IRRITANTS ON UV AND CHEMICALLY TREATED, RECONSTITUTED, THREE DIMENSIONAL HUMAN SKIN.

A great need exists in the cosmetics industry for in vitro screening methods that can provide accurate predictions of potential product or ingredient irritation. A variety of in vitro methods exist that utilize cell cultures, some of these focusing on... Read More

Reference Libraries

1-(2,4-DIHYDROXYPHENYL)-3-(2,4-DIMETHOXY-3-METHYL-PHENYL)PROPANE, A NOVEL TYROSINASE INHIBITOR WITH STRONG DEPIGMENTING EFFECTS.

EVALUATION OF EPIDERM™ AS A MODEL TO STUDY IRRITATION AFTER EXPOSURE TO VARIOUS ALIPHATIC HYDROCARBONS FOUND IN JET FUELS.

DEVELOPMENT OF AN IN VITRO MODEL FOR THE PREDICTION OF SKIN IRRITATION POTENTIAL.

Skin irritation and potential efficacy of a novel compound for localized treatment of psoriasis

AN IN VITRO METHOD FOR SCREENING ANTI-IRRITANTS ON UV AND CHEMICALLY TREATED, RECONSTITUTED, THREE DIMENSIONAL HUMAN SKIN.

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