Reference Libraries

December 11, 2015

WOUND HEALING AND EXPRESSION OF ANTIMICROBIAL PEPTIDES/ POLYPEPTIDES IN HUMAN KERATINOCYTES, A CONSEQUENCE OF COMMON GROWTH FACTORS.

In addition to acting as a physical barrier against microorganisms, the skin produces antimicrobial peptides and proteins. After wounding, growth factors are produced to stimulate the regeneration of tissue. The growth factor response ceases after regeneration of the tissue, when... Read More

December 11, 2015

DNA photoprotection conveyed by sunscreen

Introduction: Skin photoaging is the consequence of solar UV exposure, and DNA damage is an important part of this process. The objective of the current work was to demonstrate that in vitro skin models can be utilized to confirm that... Read More

December 11, 2015

CONTRIBUTION OF UVB AND UVA TO UV- DEPENDENT STIMULATION OF CYCLOOXYGENASE-2 EXPRESSION IN ARTIFICIAL EPIDERMIS.

Both UVB (280–320 nm) and UVA (320–400 nm) radiation lead to an enhanced expression of cyclooxygenase-2 (COX-2) in epidermal cells in various in-vitro and in-vivo models. It is demonstrated here that the expression of COX-2 is induced in artificial human... Read More

December 11, 2015

PREVENTION OF VAGINAL SHIV TRANSMISSION IN MACAQUES BY A LIVE RECOMBINANT LACTOBACILLUS.

Most human immunodeficiency virus (HIV) transmissions in women occur through the cervicovaginal mucosa, which is coated by a bacterial biofilm including Lactobacillus . This commensal bacterium has a role in maintaining a healthy mucosa and can be genetically engineered to... Read More

December 11, 2015

EVALUATION OF IN VITRO MODELS FOR REACH TOXICITY TESTING: INDUCIBILITY OF XENOBIOTIC METABOLIZING ENZYME (XME) ACTIVITY IN IN VITRO HUMAN AIRWAY (EPIAIRWAY™) AND EPIDERMAL (EPIDERM™) MODELS.

Dermal and airway epithelia contain XMEs including phase I (oxidative) and phase II (conjugative) activities. These XMEs may play a role in biotransformation of drugs and chemicals, leading to altered drug activity or formation of toxic/mutagenic metabolites. Consideration of metabolic... Read More

Reference Libraries

WOUND HEALING AND EXPRESSION OF ANTIMICROBIAL PEPTIDES/ POLYPEPTIDES IN HUMAN KERATINOCYTES, A CONSEQUENCE OF COMMON GROWTH FACTORS.

DNA photoprotection conveyed by sunscreen

CONTRIBUTION OF UVB AND UVA TO UV- DEPENDENT STIMULATION OF CYCLOOXYGENASE-2 EXPRESSION IN ARTIFICIAL EPIDERMIS.

PREVENTION OF VAGINAL SHIV TRANSMISSION IN MACAQUES BY A LIVE RECOMBINANT LACTOBACILLUS.

EVALUATION OF IN VITRO MODELS FOR REACH TOXICITY TESTING: INDUCIBILITY OF XENOBIOTIC METABOLIZING ENZYME (XME) ACTIVITY IN IN VITRO HUMAN AIRWAY (EPIAIRWAY™) AND EPIDERMAL (EPIDERM™) MODELS.

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