Reference Libraries

December 11, 2015

NOREPINEPHRINE MODULATES HUMAN DENDRITIC CELL ACTIVATION BY ALTERING CYTOKINE RELEASE.

This study by researchers at Weill Medical College of Cornell University and Clinique Laboratories demonstrated how MatTek’s Human Dendritic Cells can be used to observe the effect of a specific compound (norepinephrine) on the cytokine expression of cells that are... Read More

December 11, 2015

COLCHICINE PROMOTES ANTIGEN CROSS-PRESENTATION BY MURINE DENDRITIC CELLS.

This study by researchers at the University of Texas Southwestern Medical Center demonstrated that MatTek’s Human Langerhans/Dendritic Cells are an excellent in vitro model for investigating and predicting the likely interactions of drugs (Colchicine) with human dendritic cells. Colchicine (COL)... Read More

December 11, 2015

HUMAN INTESTINAL DENDRITIC CELLS DECREASE CYTOKINE RELEASE AGAINST SALMONELLA INFECTION IN THE PRESENCE OF LACTOBACILLUS PARACASEI UPON TLR ACTIVATION.

Probiotic bacteria have been shown to modulate immune responses and could have therapeutic effects in allergic and inflammatory disorders. However, little is known about the signaling pathways that are engaged by probiotics. Dendritic cells (DCs) are antigen-presenting cells that are... Read More

December 11, 2015

DYNAMIC AND PHYSICAL CLUSTERING OF GENE EXPRESSION DURING EPIDERMAL BARRIER FORMATION IN DIFFERENTIATING KERATINOCYTES.

The mammalian epidermis is a continually renewing structure that provides the interface between the organism and an innately hostile environment. The keratinocyte is its principal cell. Keratinocyte proteins form a physical epithelial barrier, protect against microbial damage, and prepare immune... Read More

December 11, 2015

ASSURING SAFETY WITHOUT ANIMAL TESTING: DEVELOPMENT OF MECHANISTIC UNDERSTANDING OF DENDRITIC CELL ACTIVATION RESPONSE TO CHEMICAL SENSITISERS.

Assuring consumer safety without the generation of new animal data is currently a considerable challenge but one that we believe is ultimately achievable. Skin allergy (sensitisation) is an important consumer safety endpoint for home and personal care products and an... Read More

Reference Libraries

NOREPINEPHRINE MODULATES HUMAN DENDRITIC CELL ACTIVATION BY ALTERING CYTOKINE RELEASE.

COLCHICINE PROMOTES ANTIGEN CROSS-PRESENTATION BY MURINE DENDRITIC CELLS.

HUMAN INTESTINAL DENDRITIC CELLS DECREASE CYTOKINE RELEASE AGAINST SALMONELLA INFECTION IN THE PRESENCE OF LACTOBACILLUS PARACASEI UPON TLR ACTIVATION.

DYNAMIC AND PHYSICAL CLUSTERING OF GENE EXPRESSION DURING EPIDERMAL BARRIER FORMATION IN DIFFERENTIATING KERATINOCYTES.

ASSURING SAFETY WITHOUT ANIMAL TESTING: DEVELOPMENT OF MECHANISTIC UNDERSTANDING OF DENDRITIC CELL ACTIVATION RESPONSE TO CHEMICAL SENSITISERS.

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