Reference Libraries

December 11, 2015

COLIPA PROGRAM ON OPTIMIZATION OF EXISTING IN VITRO EYE IRRITATION ASSAYS FOR ENTRY INTO FORMAL VALIDATION: TECHNOLOGY TRANSFER AND INTRA/INTER LABORATORY EVALUATION OF EPIOCULAR ASSAY FOR CHEMICALS.

This study by scientists at Mary Kay, Inc., COLIPA (European Cosmetics Association), Procter & Gamble Co. and MatTek Corp. demonstrated that MatTek’s EpiOcular in vitro human corneal tissue equivalent is a very accurate and reproducible in vitro model for the... Read More

December 11, 2015

USE OF THE EPIOCULAR ASSAY FOR PRECLINICAL QUALIFICATION OF FORMULAS FOR HUMAN CLINICAL STUDIES.

This study by researchers at Mary Kay Cosmetics demonstrated that MatTek’s EpiOcular human cornea-like tissue construct can be used to accurately predict the irritation potential of cosmetic products designed to be applied on human skin immediately adjacent to the eye... Read More

December 11, 2015

THE UTILIZATION OF THE EPIOCULAR HUMAN TISSUE MODEL TO ASSESS AND COMPARE THE IRRITATION POTENTIAL OF MULTIPLE SURFACTANT SYSTEMS USED IN SHAMPOOS AND FACIAL CLEANSERS.

This study by scientists at Alberto-Culver Company and the Institute for In Vitro Sciences demonstrated that MatTek’s EpiOcular in vitro human corneal tissue equivalent is an excellent in vitro model for performing the ocular safety evaluation of multiple surfactant systems... Read More

December 11, 2015

REPRODUCIBILITY OF EPIAIRWAY™, A DIFFERENTIATED AIRWAY TISSUE MODEL FOR PRE-CLINICAL DRUG DEVELOPMENT STUDIES.

RATIONALE: Normal human tracheal-bronchial epithelial cells (NHBE) are cultured using serum free medium to form EpiAirway, a three dimensional tissue that closely resembles the epithelial tissue of the respiratory tract. Data was collected by scientists at SUNY Stony Brook and... Read More

December 11, 2015

DRUG/XENOBIOTIC-METABOLIZING ENZYME (XME) EXPRESSION IN THE EPIAIRWAY IN VITRO HUMAN AIRWAY MODEL: UTILITY FOR ASSESSING TRACHEAL/BRONCHIAL BIOTRANSFORMATION OF INHALED PHARMACEUTICALS AND ENVIRONMENTAL CHEMICALS.

This study by MatTek Corp. scientists demonstrated that MatTek’s EpiAirway human airway tissue equivalent possesses numerous in vivo-like xenobiotic metabolizing enzyme (XME) activities and therefore should be useful for evaluating the airway metabolism of drugs, tobacco smoke and environmental/occupational chemicals.... Read More

Reference Libraries

COLIPA PROGRAM ON OPTIMIZATION OF EXISTING IN VITRO EYE IRRITATION ASSAYS FOR ENTRY INTO FORMAL VALIDATION: TECHNOLOGY TRANSFER AND INTRA/INTER LABORATORY EVALUATION OF EPIOCULAR ASSAY FOR CHEMICALS.

USE OF THE EPIOCULAR ASSAY FOR PRECLINICAL QUALIFICATION OF FORMULAS FOR HUMAN CLINICAL STUDIES.

THE UTILIZATION OF THE EPIOCULAR HUMAN TISSUE MODEL TO ASSESS AND COMPARE THE IRRITATION POTENTIAL OF MULTIPLE SURFACTANT SYSTEMS USED IN SHAMPOOS AND FACIAL CLEANSERS.

REPRODUCIBILITY OF EPIAIRWAY™, A DIFFERENTIATED AIRWAY TISSUE MODEL FOR PRE-CLINICAL DRUG DEVELOPMENT STUDIES.

DRUG/XENOBIOTIC-METABOLIZING ENZYME (XME) EXPRESSION IN THE EPIAIRWAY IN VITRO HUMAN AIRWAY MODEL: UTILITY FOR ASSESSING TRACHEAL/BRONCHIAL BIOTRANSFORMATION OF INHALED PHARMACEUTICALS AND ENVIRONMENTAL CHEMICALS.

Get the latest