December 11, 2015
Reference Libraries
December 11, 2015
USE OF EPIDERM™ AS AN INFLAMMATORY MODEL FOR PRE-CLINICAL SCREENING.
Organotypic skin models are becoming widely used by the pharmaceutical and cosmetics industries as an alternative to animal testing for screening cosmetics and potential therapeutics for safety and efficacy. The purpose of this study was to test if MatTek’s EpiDerm... Read More
December 11, 2015
ULTRAVIOLET B RADIATION UPREGULATES THE PRODUCTION OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) IN HUMAN EPIDERMAL KERATINOCYTES.
Human epidermal cells are capable of secreting various cytokines with immunologic, inflammatory, and proliferative properties. In a previous study, by reverse transcription-polymerase chain reaction and immunohistochemical analysis, we have shown that human epidermal keratinocytes express macrophage migration inhibitory factor and... Read More
December 11, 2015
AVOCADO PHYTOSTEROLS DECREASE UVB-INDUCED PRO-INFLAMMATORY MEDIATORS.
Exposure of skin to UVB radiation can cause the production of pro-inflammatory cytokines and prostanoids. Changes in the production of these mediators in the skin can decrease or increase the potentially damaging effects of UVB irradiation. In this series of... Read More
December 11, 2015
IDENTIFICATION OF INTELLIGENT BIOMARKERS OF EXPOSURE AND HARM IN THE RESPIRATORY EPITHELIAL TO TOBACCO SMOKE COMPONENTS.
This study by researchers in the Cardiff University School of Biosciences (Wales/UK) demonstrated how MatTek’s EpiAirway in vitro human tracheal/ bronchial tissue equivalent can be used to study the early gene response of human respiratory epithelia to tobacco smoke component... Read More