Reference Libraries

December 11, 2015

THE FIBROBLAST-DERIVED PARACRINE FACTOR NEUREGULIN-1 HAS A NOVEL ROLE IN REGULATING THE CONSTITUTIVE COLOR AND MELANOCYTE FUNCTION IN HUMAN SKIN.

Interactions between melanocytes and neighboring cells in the skin are important in regulating skin color in humans. We recently demonstrated that the less pigmented and thicker skin on the palms and soles is regulated by underlying fibroblasts in those areas,... Read More

December 11, 2015

A COMPARISON STUDY OF FOUR IN VITRO PHOTOTOXICITY SYSTEMS.

Four in vitro phototoxicity systems were evaluated to determine how closely each method would reproduce the others. Eleven materials were used to evaluate these methods. All eleven materials were run in each system. Phototoxicity was evaluated using the MatTek EPI-100... Read More

December 11, 2015

USE OF THE MATTEK EPI-100 IN VITRO SYSTEM TO SCREEN ANTIOXIDANT EFFICACY.

In this study, scientists at R. Thomas Stephens & Associates present an in vitro method to evaluate the efficacy of antioxidants and antioxidant formulations. The premise of this research is that exposure of human skin equivalents, specifically the commercially available... Read More

December 11, 2015

AN ASSESSMENT OF THE PHOTOTOXIC HAZARD OF A PERSONAL PRODUCT INGREDIENT USING IN VITRO ASSAYS.

Where substances are intended for use in personal products applied to the skin an assessment of potential phototoxic hazard is required. This report describes a tiered testing strategy involving in vitro assays used for the phototoxic hazard assessment of a... Read More

December 11, 2015

A TIERED STRATEGY FOR IN VITRO PHOTOTOXICITY TESTING.

Of the materials used to demonstrate the value of the 3-D Skin Assay (in supporting and interpreting 3T3 NRU PT results), all of those predicted phototoxic in the 3T3 NRU PT were confirmed phototoxic in the 3-D Skin Assay, with... Read More

Reference Libraries

THE FIBROBLAST-DERIVED PARACRINE FACTOR NEUREGULIN-1 HAS A NOVEL ROLE IN REGULATING THE CONSTITUTIVE COLOR AND MELANOCYTE FUNCTION IN HUMAN SKIN.

A COMPARISON STUDY OF FOUR IN VITRO PHOTOTOXICITY SYSTEMS.

USE OF THE MATTEK EPI-100 IN VITRO SYSTEM TO SCREEN ANTIOXIDANT EFFICACY.

AN ASSESSMENT OF THE PHOTOTOXIC HAZARD OF A PERSONAL PRODUCT INGREDIENT USING IN VITRO ASSAYS.

A TIERED STRATEGY FOR IN VITRO PHOTOTOXICITY TESTING.

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