Reference Libraries

August 29, 2024

Ionic liquids as a class of materials for transdermal delivery and pathogen neutralization

Biofilm-protected microbial infections in skin are a serious health risk that remains to be adequately addressed. The lack of progress in developing effective treatment strategies is largely due to the transport barriers posed by the stratum corneum of the skin... Read More

August 29, 2024

Cytotoxicity and Bioimmunological Activity of Poly(2-Isopropenyl-2- oxazoline) Conjugates with Ibuprofen Using 3D Reconstructed Tissue Models

Poly(2-isopropenyl-2-oxazoline) (PIPOx) represents a universal polymer platform with pendant 2-oxazoline groups, allowing the preparation of biomaterials for various biomedical applications. However, there is a lack of information on PIPOx concerning the effect of molar mass (Mn) on cytotoxicity and bioimmunological... Read More

August 29, 2024

Evaluation of skin irritation potentials of different cosmetic products in Turkish market by reconstructed human epidermis model

Human skin is a protective barrier against the toxic effects of cosmetics. Marketing of cosmetic products with ingredients tested on animals was prohibited in 2013. Since then, safety evaluation of cosmetic products is performed by using alternative in vitro toxicity... Read More

August 29, 2024

Mucoadhesive chitosan-poly (lactic-co-glycolic acid) nanoparticles for intranasal delivery of quetiapine – Development & characterization in physiologically relevant 3D tissue models

Quetiapine hemifumarate (QF) delivery to the CNS via conventional formulations is challenging due to poor solubility and lower oral bioavailability (9 %). Similarly, many other second-generation antipsychotics, such as olanzapine, clozapine, and paliperidone, have also shown low oral bioavailability of... Read More

August 29, 2024

Novel Organotypic Patient-Derived Primary Tumor Tissues for Oncology Drug Safety and Efficacy Studies

Organotypic, three-dimensional (3D) cancer tissue models (OCTM) have enabled investigators to develop predictive markers that can be used in preclinical cancer drug development. However, a drawback of the existing models is that they are mostly cell line-based are not physiologic.... Read More

Reference Libraries

Ionic liquids as a class of materials for transdermal delivery and pathogen neutralization

Cytotoxicity and Bioimmunological Activity of Poly(2-Isopropenyl-2- oxazoline) Conjugates with Ibuprofen Using 3D Reconstructed Tissue Models

Evaluation of skin irritation potentials of different cosmetic products in Turkish market by reconstructed human epidermis model

Mucoadhesive chitosan-poly (lactic-co-glycolic acid) nanoparticles for intranasal delivery of quetiapine – Development & characterization in physiologically relevant 3D tissue models

Novel Organotypic Patient-Derived Primary Tumor Tissues for Oncology Drug Safety and Efficacy Studies

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