Reference Libraries

December 11, 2015

MATRIX METALLOPROTEINASE (MMP) EXPRESSION IN THE EPIDERM-FT SKIN EQUIVALENT: RELEVANCE TO DERMAL WOUND HEALING AND BLISTERING SKIN DISEASES.

Using MatTek’s EpiDermFT full-thickness in vitro human skin equivalent, scientists at MatTek Corp. showed that epidermal keratinocytes have a significant influence over the expression of matrix metalloproteinases (MMP’s) by dermal fibroblasts, demonstrating why EpiDermFT is useful in investigating MMP expression... Read More

December 11, 2015

EPIDERM™ FULL THICKNESS (EPIDERMFT™), A DERMAL/EPIDERMAL SKIN EQUIVALENT WITH A FULLY DEVELOPED BASEMENT MEMBRANE.

Paracrine signaling between dermal fibroblasts and epidermal keratinocytes is believed to modulate skin responses during contact irritant or allergic reactions. Dermal fibroblasats also play an important role in photo-aging and photo-damage, wound healing and cancer progression. To enable in vitro... Read More

December 11, 2015

WOUND HEALING RESPONSE OF A FULL THICKNESS IN VITRO HUMAN SKIN EQUIVALENT (EPIDERM-FT™ 200) AFTER SOLAR UV-IRRADIATION.

Normal human epidermal keratinocytes (KC) and dermal fibroblasts (FB) were cultured to produce full-thickness skin equivalents with FB-containing dermal and stratified epidermal components and fully developed basement membrane at the dermal/epidermal junction (EpiDermFT 200). The wound healing response of EpiDermFT... Read More

December 11, 2015

EFFECTS OF GUAIFENESIN, N-ACETYLCYSTEINE, AND AMBROXOL ON MUC5AC AND MUCOCILIARY TRANSPORT IN PRIMARY DIFFERENTIATED HUMAN TRACHEAL-BRONCHIAL CELLS.

Background: Therapeutic intervention in the pathophysiology of airway mucus hypersecretion is clinically important. Several types of drugs are available with different possible modes of action. We examined the effects of guaifenesin (GGE), N-acetylcysteine (NAC) and ambroxol (Amb) on differentiated human... Read More

December 11, 2015

HIGHER LEVEL OF REPLICATION EFFICIENCY OF 2009 (H1N1) PANDEMIC INFLUENZA VIRUS THAN THOSE OF SEASONAL AND AVIAN STRAINS: KINETICS FROM EPITHELIAL CELL CULTURE AND COMPUTATIONAL MODELING.

The pathogenicity and transmission of influenza A viruses are likely determined in part by replication efficiency in human cells, which is the net effect of complex virus-host interactions. H5N1 avian, H1N1 seasonal, and H1N1 2009 pandemic influenza virus strains were... Read More

Reference Libraries

MATRIX METALLOPROTEINASE (MMP) EXPRESSION IN THE EPIDERM-FT SKIN EQUIVALENT: RELEVANCE TO DERMAL WOUND HEALING AND BLISTERING SKIN DISEASES.

EPIDERM™ FULL THICKNESS (EPIDERMFT™), A DERMAL/EPIDERMAL SKIN EQUIVALENT WITH A FULLY DEVELOPED BASEMENT MEMBRANE.

WOUND HEALING RESPONSE OF A FULL THICKNESS IN VITRO HUMAN SKIN EQUIVALENT (EPIDERM-FT™ 200) AFTER SOLAR UV-IRRADIATION.

EFFECTS OF GUAIFENESIN, N-ACETYLCYSTEINE, AND AMBROXOL ON MUC5AC AND MUCOCILIARY TRANSPORT IN PRIMARY DIFFERENTIATED HUMAN TRACHEAL-BRONCHIAL CELLS.

HIGHER LEVEL OF REPLICATION EFFICIENCY OF 2009 (H1N1) PANDEMIC INFLUENZA VIRUS THAN THOSE OF SEASONAL AND AVIAN STRAINS: KINETICS FROM EPITHELIAL CELL CULTURE AND COMPUTATIONAL MODELING.

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