Reference Libraries

April 2, 2025

Human organotypic colon in vitro microtissue: unveiling a new window into colonic drug disposition

The purpose of this study was to evaluate EpiColon, a novel human organotypic 3D colon microtissue prototype, developed to assess colonic drug disposition, with a particular focus on permeability ranking, and compare its performance to Caco-2 monolayers. EpiColon was characterized... Read More

April 2, 2025

In Vitro Inhalation Toxicity Assay of Azoxystrobin 23% SC and Spinetoram 11.7% SC using EpiAirwayTM

Inhalation is one of the major routes for the evaluation of hazards of a xenobiotic since the lung is an important route for exposure of chemicals and crop protection products. Crop protection products, such as Azoxystrobin 23% SC and Spinetoram... Read More

April 2, 2025

Worldwide reproducibility of a highly differentiated 3-dimensional vaginal tissue model for testing of feminine hygiene products

When making risk and hazard assessments of new ingredients or finished products, reproducibility of the toxicology test system is of extreme importance to regulators, in-house toxicologists, and formulation scientists. One of the advantages of in vitro test systems vis-à-vis animal-based... Read More

March 27, 2025

Development of an In Vitro Method for Assessing the Potential Irritation of Medical Devices and OTC Products Used in the Oral Cavity

The aim of this study was to evaluate an in vitro method using the EpiOralTM model, a three-dimensional cultured human buccal epithelium, for assessing the oral irritation potential of various products. We evaluated different concentrations of nine chemicals commonly found in... Read More

March 26, 2025

Applicability of the in vitro skin irritation methods (EpiSkin™, EpiDerm™ SIT) to organosilicon-based substances

It is now widely accepted that the reconstructed human epidermis models (OECD TG 439) can be used as a standalone replacement of the in vivo rabbit assay (OECD TG 404) to accurately predict skin irritancy. Many legislations have now introduced the legal... Read More

Reference Libraries

Human organotypic colon in vitro microtissue: unveiling a new window into colonic drug disposition

In Vitro Inhalation Toxicity Assay of Azoxystrobin 23% SC and Spinetoram 11.7% SC using EpiAirwayTM

Worldwide reproducibility of a highly differentiated 3-dimensional vaginal tissue model for testing of feminine hygiene products

Development of an In Vitro Method for Assessing the Potential Irritation of Medical Devices and OTC Products Used in the Oral Cavity

Applicability of the in vitro skin irritation methods (EpiSkin™, EpiDerm™ SIT) to organosilicon-based substances

Get the latest