Reference Libraries

December 11, 2015

BARRIER FUNCTION COMPARISON BETWEEN IN VITRO SKIN, ORAL (BUCCAL), AND OCULAR TISSUE MODELS – IMPLICATIONS FOR DRUG DELIVERY STUDIES.

Purpose: Due to the barrier properties of skin, transdermal delivery of therapeutic compounds is often not feasible. As an alternative, delivery through buccal or gingival tissues has been investigated. The current presentation involves use highly differentiated, in vitro tissue models... Read More

December 11, 2015

HYDROGEN PEROXIDE MEDIATED TRANSVAGINAL DRUG DELIVERY.

Simple, safe and effective permeability enhancers are crucial for successful non-invasive drug delivery methods. We seek local permeability augmentation mechanisms for integration into passive or active architectures in order to enable novel therapeutic delivery routes of the target drug while... Read More

December 11, 2015

EVALUATION OF RECONSTITUTED HUMAN VAGINAL EPITHELIUM AS A MODEL FOR DRUG DELIVERY OF FLUCONAZOLE GEL FOR TREATING VULVOVAGINAL CANDIDIASIS.

Purpose: The goal of this project performed by researchers at the Massachusetts College of Pharmacy and Health Sciences was to evaluate the use of EpiVaginal, a reconstituted human vaginal epithelium, as a model for penetration for an antifungal gel containing... Read More

December 11, 2015

THE EFFICACY OF ECHINACEA IN A 3-D TISSUE MODEL OF HUMAN AIRWAY EPITHELIUM.

This study by researchers at the University of British Columbia and A. Vogel Bioforce AG demonstrated that MatTek’s EpiAirway in vitro 3-D human tracheal/bronchial tissue equivalent can be infected with rhinovirus type 1A (RV1A) and then used to evaluate the... Read More

December 11, 2015

RECONSTRUCTION OF NEW ORGANOTYPIC 3D HUMAN SMALL INTESTINE TISSUE MODEL FOR DRUG SAFETY AND TOXICITY.

The epithelial lining of the gastrointestinal (GI) tract is a gatekeeper for entry of orally ingested nutrients and xenobiotics including medicaments. The small intestine has a well organized structure containing proliferative cells which migrate along the crypt-villi axis and differentiate... Read More

Reference Libraries

BARRIER FUNCTION COMPARISON BETWEEN IN VITRO SKIN, ORAL (BUCCAL), AND OCULAR TISSUE MODELS – IMPLICATIONS FOR DRUG DELIVERY STUDIES.

HYDROGEN PEROXIDE MEDIATED TRANSVAGINAL DRUG DELIVERY.

EVALUATION OF RECONSTITUTED HUMAN VAGINAL EPITHELIUM AS A MODEL FOR DRUG DELIVERY OF FLUCONAZOLE GEL FOR TREATING VULVOVAGINAL CANDIDIASIS.

THE EFFICACY OF ECHINACEA IN A 3-D TISSUE MODEL OF HUMAN AIRWAY EPITHELIUM.

RECONSTRUCTION OF NEW ORGANOTYPIC 3D HUMAN SMALL INTESTINE TISSUE MODEL FOR DRUG SAFETY AND TOXICITY.

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