Reference Libraries

December 11, 2015

TRANSFER OF IgG IN THE FEMALE GENITAL TRACT BY MHC CLASS I-RELATED NEONATAL FC RECEPTOR (FCRN) CONFERS PROTECTIVE IMMUNITY TO VAGINAL INFECTION.

IgG is a major Ig subclass in mucosal secretions of the human female genital tract, where it predominates over the IgA isotype. Despite the abundance of IgG, surprisingly little is known about where and how IgG enters the lumen of... Read More

December 11, 2015

RECONSTRUCTED, DIFFERENTIATED AIRWAY EPITHELIAL CULTURES TO MODEL RESPIRATORY INFECTION.

Normal human tracheal-bronchial epithelial cells (NHBE) have been cultured using serum free medium to form a three dimensional tissue-like structure, EpiAirway, that closely resembles the epithelial tissue of the respiratory tract. Histological cross-sections of both the in vitro tissue and... Read More

December 11, 2015

IN VITRO MODEL FOR IMMUNOTOXICITY: SURFACE MARKER EXPRESSION AND CYTOKINE RELEASE IN NORMAL HUMAN DENDRITIC CELLS (DC-100).

Dendritic cells (DC) play a key role in the initiation of immune response by recognizing, internalizing, processing, and presenting antigens to T cells. However, DC function can be altered by environmental factors, pharmaceutical agents, and exogenous chemicals. These perturbations to... Read More

December 11, 2015

INHIBITION OF NIPAH VIRUS INFECTION IN VIVO: TARGETING AN EARLY STAGE OF PARAMYXOVIRUS FUSION ACTIVATION DURING VIRAL ENTRY.

In the paramyxovirus cell entry process, receptor binding triggers conformational changes in the fusion protein (F) leading to viral and cellular membrane fusion. Peptides derived from C-terminal heptad repeat (HRC) regions in F have been shown to inhibit fusion by... Read More

December 11, 2015

DISRUPTION OF TIGHT JUNCTIONS BY CELLULOSE SULFATE FACILITATES HIV INFECTION: MODEL OF MICROBICIDE SAFETY.

This study by researchers in the Departments of Pediatrics, Microbiology-Immunology and Medicine at Albert Einstein College of Medicine demonstrated that MatTek’s EpiVaginal in vitro 3-D human cervico-vaginal tissue equivalent can be used to model potential epithelial barrier disruption caused by... Read More

Reference Libraries

TRANSFER OF IgG IN THE FEMALE GENITAL TRACT BY MHC CLASS I-RELATED NEONATAL FC RECEPTOR (FCRN) CONFERS PROTECTIVE IMMUNITY TO VAGINAL INFECTION.

RECONSTRUCTED, DIFFERENTIATED AIRWAY EPITHELIAL CULTURES TO MODEL RESPIRATORY INFECTION.

IN VITRO MODEL FOR IMMUNOTOXICITY: SURFACE MARKER EXPRESSION AND CYTOKINE RELEASE IN NORMAL HUMAN DENDRITIC CELLS (DC-100).

INHIBITION OF NIPAH VIRUS INFECTION IN VIVO: TARGETING AN EARLY STAGE OF PARAMYXOVIRUS FUSION ACTIVATION DURING VIRAL ENTRY.

DISRUPTION OF TIGHT JUNCTIONS BY CELLULOSE SULFATE FACILITATES HIV INFECTION: MODEL OF MICROBICIDE SAFETY.

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