Reference Libraries

December 11, 2015

N,N-DICHLORO-2, 2-DIMETHYLTAURINE, N-MONOCHLORO-2, 2-DIMETHYLTAURINE, AND N-CHLOROTAURINE ARE SAFE AND EFFECTIVE BACTERICIDAL AGENTS IN CORNEAL MODELS.

Background: N-chlorotaurine, NVC-422 (N,N-dichloro-dimethyltaurine) and NVC-612 (N-monochloro-dimethyltaurine) are potent anti-infective agents useful for the treatment of conjunctivitis and keratitis. The aim of this study is to show that these compounds are safe in an EpiOcular model and effective in corneas... Read More

December 11, 2015

PREDICTING EYE IRRITATION OF AGROCHEMICAL FORMULATIONS ACCORDING TO DIFFERENT CLASSIFICATION SCHEMES BY IN VITRO METHODS (BOVINE CORNEAL OPACITY AND PERMEABILITY AND EPIOCULAR EYE IRRITATION TEST).

The bovine corneal opacity and permeability (BCOP) test has been adopted by OECD for the identification of corrosive and severe ocular irritants (GHS category 1) for single component substances and multicomponent formulations. Eye irritation tests with human (EIT) reconstructed tissue... Read More

December 11, 2015

CHARACTERIZATION AND TESTING OF NEW BUCCAL AND GINGIVAL TISSUE MODELS.

This study by scientists at the University of Washington, University of Iowa and MatTek Corp. demonstrated that MatTek’s EpiOral and EpiGingival in vitro human buccal and gingival oral tissue equivalents showed good correspondence to human explant buccal and gingival tissue... Read More

December 11, 2015

COSMETICS EUROPE MULTI-LABORATORY PRE-VALIDATION OF THE EPIOCULAR™ RECONSTITUTED HUMAN TISSUE TEST METHOD FOR THE PREDICTION OF EYE IRRITATION.

Cosmetics Europe, The Personal Care Association (known as Colipa before 2012), conducted a program of technology transfer andwithin/between laboratory reproducibility of MatTek Corporation’s EpiOcular™ Eye Irritation Test (EIT) as one of the two human reconstructed tissue test methods. This EIT... Read More

December 11, 2015

Evaluation of a Reconstructed Human Oral Buccal Tissue Model as a Testing Platform for Determining the Oral Irritation Potential of Tobacco Products

There is an increasing need by the tobacco industry to evaluate the irritation and inflammation potential of tobacco products to support product development goals, for sound product stewardship, and likely regulatory safety tests. The use of in vitro human cell... Read More

Reference Libraries

N,N-DICHLORO-2, 2-DIMETHYLTAURINE, N-MONOCHLORO-2, 2-DIMETHYLTAURINE, AND N-CHLOROTAURINE ARE SAFE AND EFFECTIVE BACTERICIDAL AGENTS IN CORNEAL MODELS.

PREDICTING EYE IRRITATION OF AGROCHEMICAL FORMULATIONS ACCORDING TO DIFFERENT CLASSIFICATION SCHEMES BY IN VITRO METHODS (BOVINE CORNEAL OPACITY AND PERMEABILITY AND EPIOCULAR EYE IRRITATION TEST).

CHARACTERIZATION AND TESTING OF NEW BUCCAL AND GINGIVAL TISSUE MODELS.

COSMETICS EUROPE MULTI-LABORATORY PRE-VALIDATION OF THE EPIOCULAR™ RECONSTITUTED HUMAN TISSUE TEST METHOD FOR THE PREDICTION OF EYE IRRITATION.

Evaluation of a Reconstructed Human Oral Buccal Tissue Model as a Testing Platform for Determining the Oral Irritation Potential of Tobacco Products

Get the latest