Reference Libraries

December 11, 2015

OXIDATIVE STRESS AND INFLAMMATORY RESPONSE IN DERMAL TOXICITY OF SINGLE-WALLED CARBON NANOTUBES.

This study by researchers at PPRB/NIOSH, West Virginia University and the University of Pittsburgh demonstrated that MatTek’s EpiDermFT full-thickness in vitro 3-D human skin tissue equivalent can be used to measure the dermal toxicity of single-walled carbon nanotubes (SWCNT). Single-walled... Read More

December 11, 2015

PREDICTING EYE IRRITATION OF AGROCHEMICAL FORMULATIONS ACCORDING TO DIFFERENT CLASSIFICATION SCHEMES BY IN VITRO METHODS (BOVINE CORNEAL OPACITY AND PERMEABILITY AND EPIOCULAR EYE IRRITATION TEST).

The bovine corneal opacity and permeability (BCOP) test has been adopted by OECD for the identification of corrosive and severe ocular irritants (GHS category 1) for single component substances and multicomponent formulations. Eye irritation tests with human (EIT) reconstructed tissue... Read More

December 11, 2015

ASSESSMENT OF DERMAL TOXICITY OF NANOSILICA USING CULTURED KERATINOCYTES, A HUMAN SKIN EQUIVALENT MODEL AND AN IN VIVO MODEL.

This study by researchers at Korea University College of Medicine and the National Institute of Toxicological Research (Korea) demonstrated how MatTek’s EpiDerm in vitro 3-D human skin tissue equivalent can be used to test the skin irritation potential of nanosilica... Read More

December 11, 2015

IN-HOUSE VALIDATION OF THE EPIOCULAR™ EYE IRRITATION TEST AND ITS COMBINATION WITH THE BOVINE CORNEAL OPACITY AND PERMEABILITY TEST FOR THE ASSESSMENT OF OCULAR IRRITATION.

In 2009, the Bovine Corneal Opacity and Permeability (BCOP) test was accepted by the regulatory bodies for the identification of corrosive and severe ocular irritants (Global Harmonised System [GHS] Category 1). However, no in vitro test is currently accepted for... Read More

December 11, 2015

Evaluation of a Reconstructed Human Oral Buccal Tissue Model as a Testing Platform for Determining the Oral Irritation Potential of Tobacco Products

There is an increasing need by the tobacco industry to evaluate the irritation and inflammation potential of tobacco products to support product development goals, for sound product stewardship, and likely regulatory safety tests. The use of in vitro human cell... Read More

Reference Libraries

OXIDATIVE STRESS AND INFLAMMATORY RESPONSE IN DERMAL TOXICITY OF SINGLE-WALLED CARBON NANOTUBES.

PREDICTING EYE IRRITATION OF AGROCHEMICAL FORMULATIONS ACCORDING TO DIFFERENT CLASSIFICATION SCHEMES BY IN VITRO METHODS (BOVINE CORNEAL OPACITY AND PERMEABILITY AND EPIOCULAR EYE IRRITATION TEST).

ASSESSMENT OF DERMAL TOXICITY OF NANOSILICA USING CULTURED KERATINOCYTES, A HUMAN SKIN EQUIVALENT MODEL AND AN IN VIVO MODEL.

IN-HOUSE VALIDATION OF THE EPIOCULAR™ EYE IRRITATION TEST AND ITS COMBINATION WITH THE BOVINE CORNEAL OPACITY AND PERMEABILITY TEST FOR THE ASSESSMENT OF OCULAR IRRITATION.

Evaluation of a Reconstructed Human Oral Buccal Tissue Model as a Testing Platform for Determining the Oral Irritation Potential of Tobacco Products

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