Reference Libraries

December 11, 2015

INHIBITION OF TUMOUR NECROSIS FACTOR-Á SECRETION FROM EPIDERM TISSUES BY A NOVEL SMALL MOLECULE, UTL-5D.

This study by scientists at Unitech Pharmaceuticals, Wayne State University, BioInnovation Laboratories, and the Taiwan National Defense Medical Center demonstrated that MatTek’s EpiDerm in vitro 3-D human skin tissue equivalent could be used to study the dose-dependent reduction of TNF-á... Read More

December 11, 2015

HYPERPIGMENTATION IN HUMAN SOLAR LENTIGO IS PROMOTED BY HEPARANASE-INDUCED LOSS OF HEPARAN SULFATE CHAINS AT THE DERMAL–EPIDERMAL JUNCTION.

Background: Skin pigmentation induced by ultraviolet B radiation is caused in part by inflammation mediated by cytokines secreted from keratinocytes and fibroblasts in the irradiated area. Heparanase is also activated in the irradiated skin, and this leads to loss of... Read More

December 11, 2015

DEVELOPMENT AND CHARACTERIZATION OF 3D PSORIATIC TISSUE MODEL.

Psoriasis is an inflammatory skin disease marked by hyperproliferation and abnormal keratinocyte differentiation that affects about 2% of the global population. In this study, we developed a human cell based in vitro psoriatic tissue model from psoriatic fibroblasts and normal... Read More

December 11, 2015

LACK OF PHOTOTOXICITY OF COSMETIC FORMULATIONS CONTAINING GLYCOLIC ACID IN AN IN VITRO HUMAN SKIN MODEL.

Glycolic acid (GA) is a naturally occurring product found in sugar cane and is a member of a class of chemicals known as alpha-hydroxy acids. GA has been widely used in cosmetic and dermatological formulations for over a decade. These... Read More

December 11, 2015

AN IN VITRO METHOD TO EVALUATE THE ANTIOXIDANT EFFICACY OF TOPICAL FORMULATIONS.

We have developed a method of evaluating antioxidant efficacy in vitro using a three dimensional epidermal construct (MatTek EPI-100, MatTek Corpora-tion, Ashland, MA) which contains a well defined stratum corneum with a lipid profile similar to human skin. The EPI-100... Read More

Reference Libraries

INHIBITION OF TUMOUR NECROSIS FACTOR-Á SECRETION FROM EPIDERM TISSUES BY A NOVEL SMALL MOLECULE, UTL-5D.

HYPERPIGMENTATION IN HUMAN SOLAR LENTIGO IS PROMOTED BY HEPARANASE-INDUCED LOSS OF HEPARAN SULFATE CHAINS AT THE DERMAL–EPIDERMAL JUNCTION.

DEVELOPMENT AND CHARACTERIZATION OF 3D PSORIATIC TISSUE MODEL.

LACK OF PHOTOTOXICITY OF COSMETIC FORMULATIONS CONTAINING GLYCOLIC ACID IN AN IN VITRO HUMAN SKIN MODEL.

AN IN VITRO METHOD TO EVALUATE THE ANTIOXIDANT EFFICACY OF TOPICAL FORMULATIONS.

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