Cultureware
Antiepileptic drugs reduce efficacy of methotrexate chemotherapy by downregulation of reduced folate carrier transport activity
- TR Number: 2013
- Authors: S. Halwachs; I. Schaefer; P. Seibel; and W. Honscha
- Keywords: Drug resistance; methotrexate; antiepileptic drugs; reduced folate carrier; transport; regulation
- Institution: University of Leipzig
- Link to Article: http://www.nature.com/leu/journal/v23/n6/pdf/leu20096a.pdf#
- Part Number Cited: glass bottom dishes (MatTek Corporation; Ashland; MA; USA)
- Microscopy Technique: Confocal microscopy
- Pub Name: Leukemia
- Volume: 23
- Issue: 6
- Year: 2009
- Cell Line: HPCT-1E3 cells
- Part No: P35G-1.5-20-C
Reference Application
- Absorption
- Antimicrobial
- Buccal delivery
- Genotoxicity
- Mucosal delivery
- Reproducibility - skin tissue models
- UV protection
- Corneal Drug Delivery
- UV damage
- transporters
- Regulatory Approval
- Review Article
- LOAEL
- Drug delivery
- Infectious disease research
- Buccal drug delivery
- Pharmacotoxicology
- Nasal absorption
- Nanotechnology
- Aging
- Respiratory Disease
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- Mucosal irritation
- Psoriasis
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- Respiratory immunotoxicity
- Human-on-a-chip
- Atopic Dermatitis
- DNA Damage
- Colitis
- Drug ADME
- Hair Growth
- scalp health
- Permeation
- Infections
- Cosmetics
- Metabolism
- Mucous
- Respiratory infection
- Viral Infection
- Melanogenesis
- Antiviral
- Gastrointestinal Disease
- Hazard assessment
- Biomedical Devices
- artificial saliva
- Skin irritation
- Toxicity
- Cytokine analysis
- Immulogical research
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- MMPs
- Intestinal Permeation
- Bacterial colonization
- Translational toxicology
- Dry skin
- drug skin compatibility
- bacterial adherence
- Allergenicity
- Antioxidants
- Drug absorption
- Immunologicaal research
- Toxicology
- Skin cancer
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- Electrolyzed Water
- Transbuccal drug delivery
- XtraMild skin mildness testing
- Skin moisturization
- Protein Expression
- PBPK Modeling
- Immunological Research
- Apoptosis
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- Skin corrosion
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- bacterial vaginosis
- ADME
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- anti-wrinkling
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- reproducibility
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- Skin re-epithelization
- Crohn's Disease
- Inflammatory response
- respiratory irritation
- UV toxicity
- Basic respiratory research
- Genomics
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- Reproducibility - eye (ocular) tissue model
- UV light
- Irritation>Eye Irritation OECD TG 492
- Skin differentiation
- Barrier repair
- Inflamed Bowel Disease
- Visible Light
- pesticides
Reference Product
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