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July 16, 2018

Validation of the In Vitro Reconstructed Skin Micronucleus Assay as a Potential Animal Alternative for Fragrance Materials

The in vitro reconstructed skin micronucleus assay is a skin-based assay which measures the clastogenicity and aneugenicity potential of...

July 16, 2018

The EpiDerm Skin Irritation Test 3 (EpiDerm SIT)

Skin irritation is defined in vivo as the reversible damage to the skin following the application of a...

July 16, 2018

The EpiDerm Phototoxicity Test (EpiDerm H3D-PT)

Phototoxicity is defined as a toxic response from a substance applied to the body which is either...

April 12, 2018

Topical Application of Self-delivering RNAi (sd-rxRNA®) Compounds for Reduction of Hyperpigmentation

There are a number of dermal hyperpigmentation disorders that have a potentially negative impact on a person’s...

April 12, 2018

The EpiDerm Skin Corrosion Test (EpiDerm SCT)

The potential for chemical induced skin corrosion is an important consideration in establishing procedures for the safe...