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December 11, 2015

EFFECT OF A NEW BOTANICAL EXTRACT BASED ON THE RED ALGAE, PIKEA ROBUSTA, ON IN VIVO REDUCTION OF SURFACTANT-INDUCED SKIN IRRITATION.

Through millions of years of evolution, organisms have developed various biochemical mechanisms to combat environmental pollutants and...

December 11, 2015

IL-1α AND IL-1ra SECRETION FROM EPIDERMAL EQUIVALENTS AND THE PREDICTION OF THE IRRITATION POTENTIAL OF MILD SOAP AND SURFACTANT-BASED CONSUMER PRODUCTS.

Scientists at Johnson & Johnson Consumer Products and Neutrogena Corp. previously evaluated the measurement of viability and...

December 11, 2015

EVALUATION OF A NEW ALTERNATIVE TO PRIMARY DRAIZE SKIN IRRITATION TESTING USING THE EPIDERM SKIN MODEL.

EpiDerm™ is a commercially available human skin model consisting of normal human-derived epidermal keratinocytes (NHEK), which have...

December 11, 2015

USE OF DIFFERENTIATED EPIDERMAL CULTURES FOR THE EXAMINATION OF INFANT-FECES-INDUCED SKIN IRRITATION.

Infant feces (BM) is known to possess a multitude of skin irritants. The aim of this study...

December 11, 2015

PROTEOMIC AND MICROARRAY INVESTIGATION TO IDENTIFY POTENTIAL IN VITRO ENDPOINTS FOR SKIN IRRITATION.

There is a need to investigate the mechanistic basis of the human skin irritation response if relevant...