Normal Human Melanocytes
MatTek’s Normal Human Melanocytes (NHM) and Growth Medium (NHM-GM) provide an optimized platform for screening actives that affect skin pigmentation. Results obtained with MatTek’s NHM can be transferred to our 3D MelanoDerm tissue model for superior product development. Available from neonatal or adult donors across a variety of ethnicities, MatTek’s NHMs offer quality and convenience for the study of melanogenesis, compound screening, toxicity testing and product development.
Donor matched keratinocytes (NHEK) & fibroblasts (NHDF) are available upon request.
MatTek’s NHMs are isolated from neonatal (NHM-CRY-NEO) or adult (NHM-CRY-AD) donor tissue and cryopreserved. When cultured in NHM-GM Growth Medium according to the MatTek NHM protocol, our melanocytes are guaranteed to have ≥ 75% viability upon thaw and to provide ≥ 12 population doublings. NHMs are characterized by their dendritic morphology and expression of MEL-5.
Download the Human Melanocytes Data Sheet
All cells are negative for mycoplasma, bacteria, yeast, and fungi. HIV-1, hepatitis B and hepatitis C are not detected by PCR for all donors and cell lots. This product is for research use only. Not for use in animals, humans or diagnostic purposes.
MatTek’s cryopreserved cells are shipped on dry ice. Cells are shipped every Monday, Tuesday and Wednesday.