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    • Tissue Models
      • EpiAirway™
      • EpiAlveolar™
      • EpiCorneal™
      • EpiDerm™
      • EpiDermFT™
      • EpiGingival™
      • EpiIntestinal™
      • EpiOcular™
      • EpiOral™
      • EpiNasal™
      • EpiVaginal™
      • MelanoDerm™
      • Melanoma
      • Psoriasis
    • Primary Cells & Media
      • Normal Human Epidermal Keratinocytes
      • Normal Human Melanocytes
      • Normal Human Dermal Fibroblasts
      • Normal Human Bronchial Epithelial Cells
      • Normal Human Bronchial Fibroblasts
      • Human Dendritic Immune Cells
      • Normal Human Corneal Epithelial Cells
    • Cultureware
      • Multi-Well Plates
      • Glass Bottom Dishes
      • Chambered Cell Culture Slides
      • PermaCell Cell Culture Inserts
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  • Services
    • Toxicology
      • Skin Irritation (OECD TG 439)
      • Skin Irritation (MTT ET-50)
      • Skin Corrosion (OECD TG 431)
      • Phototoxicity
      • Eye Irritation Test (OECD TG 492)
      • Eye Irritation (MTT ET-50)
      • Oral Irritation
      • Inhalation Toxicology
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  • Applications
    • Dermal
      • Skin Irritation (OECD TG 439)
      • Skin Irritation (MTT ET-50)
      • Skin Corrosion (OECD TG 431)
      • Skin Irritation for Medical Device Extracts (ISO 10993-23:2021)
      • Phototoxicity (OECD TG 498)
      • Skin Hydration
      • Anti-Aging
      • Skin Brightening
      • Pigmentation Studies
      • Dermal Drug Delivery
      • Genotoxicity
      • Anti-Psoriasis Drug Screening
      • Anti-Melanoma Drug Screening
      • Tumor Invasion
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    • Ocular
      • Eye Irritation Test (OECD TG 492)
      • Eye Irritation (MTT ET-50)
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    • Oral
      • Oral Irritation
      • Absorption
      • Oral Candidiasis
      • Drug Delivery (Oral Mucosal)
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    • Intestinal
      • Epithelial Restitution
      • Intestinal Fibrosis
      • Drug Metabolism
      • Drug Delivery (Intestinal)
      • Inflammation
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    • Respiratory
      • Respiratory Infection
      • Drug Delivery
      • Inhalation Toxicology
      • Inflammation and Fibrosis
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    • Vaginal
      • Vaginal Inflammation
      • Vaginal Microbicide Testing
      • Feminine Hygiene
      • STD Infection
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    • Immune Cell
      • Allergenicity Testing
      • Microbial Infection
      • Basic DC Research
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Tissue Models

EpiCorneal™

EpiCorneal™

One of the newest MatTek tissue models. Initial data indicates that EpiCorneal tissue model can effectively provide a non-animal means to assess ocular irritation, drug delivery, endomicrobial and other infections, as well as wound healing and tissue regeneration studies.

OVERVIEW
EpiOcular™

EpiOcular™

EpiOcular’s exceptional reproducibility provides scientists with quantifiable assessments of irritation. Its correlation to in vivo sensitivity makes it an ideal alternative to in vivo testing for toxicological evaluation of raw materials and final formulations.

OVERVIEW
EpiOral™ & EpiGingival™

EpiOral™ & EpiGingival™

Various industrial and toxicology laboratories are actively seeking alternatives to expensive clinical or whole animal testing. Oral care, personal care, and pharmaceutical companies have initiated in vitro toxicology testing to evaluate their raw materials and final product formulations.

OVERVIEW
EpiNasal™

EpiNasal™

EpiNasal is a ready-to-use, 3D tissue model cultured using normal, human-derived nasal epithelial cells to provide researchers with a human-relevant, in vitro nasal system. EpiNasal recapitulates the in vivo mucociliary phenotype and its barrier, and infection and toxicity responses parallel those of native tissue. Cultured at the air liquid interface, EpiNasal allows for physiological exposures to pathogens, chemicals, and therapeutics.

OVERVIEW
EpiAirway™

EpiAirway™

MatTek’s 3D tissue models of the human airway are advancing in vitro respiratory research worldwide. Allowing for physiological exposures to pathogens, chemicals or therapeutics, EpiAirway’s human-relevant biological responses are changing the way scientists research respiratory diseases and drug development. Let EpiAirway advance your science.

OVERVIEW
EpiDermFT™

EpiDermFT™

The development of innovative skin care products requires advanced, human-relevant in vitro testing technologies. When world leading personal care and cosmetic scientists evaluate novel ingredients and formulations, they choose the EpiDermFT 3D human skin model.

OVERVIEW
EpiDerm™

EpiDerm™

MatTek’s patented EpiDerm system is the leading in vitro testing technology for dermal toxicologists and formulation scientists. With multiple ECVAM validations and OECD accepted test guidelines, EpiDerm is a proven in vitro model system for chemical, pharmaceutical and skin care product testing.

OVERVIEW
MelanoDerm™

MelanoDerm™

Ideal for the assessment of skin brightening agents and formulations, MelanoDerm is used by cosmetic scientists worldwide. Reduce the time and costs associated with clinical testing by screening compounds and formulations in MatTek’s MelanoDerm 3D tissue model.

OVERVIEW
Psoriasis

Psoriasis

Psoriasis is a chronic inflammatory skin disease characterized by epidermal hyperplasia (Acanthosis). MatTek has developed an in vitro model of Psoriasis to enable the study of the disease, and to screen therapeutic candidates for safety and efficacy.

OVERVIEW
EpiIntestinal™

EpiIntestinal™

MatTek’s 3D tissue model of the human small intestine is advancing in vitro GI research worldwide. Allowing for physiological exposures and human-relevant endpoints, EpiIntestinal is being added to pharmaceutical development and microbiome discovery programs worldwide. Key features:

  • Epithelial Polarity
  • Highly Differentiated, Physiologically Relevant
  • Multiple Donors Available
  • Delivered Ready-to-use & Easy-to-use
OVERVIEW
EpiVaginal™

EpiVaginal™

EpiVaginal provides an in vitro research tool both for feminine product safety testing and for the study of HIV-1 and other sexually transmitted diseases. Its tissue structure and cellular physiology closely parallel in vivo vaginal epithelial tissue, making it ideal for toxicology and efficacy testing, as well as a tool for biological research.

OVERVIEW

MatTek’s microphysiological systems of human epithelial tissues are living, metabolically active 3D tissue models allowing researchers the flexibility of acute or long-term experiments in a highly physiological and in vitro setting.

  • EpiCorneal™
  • EpiOcular™
  • EpiOral™ & EpiGingival™
  • EpiNasal™
  • EpiAirway™
  • EpiDermFT™
  • EpiDerm™
  • MelanoDerm™
  • Psoriasis
  • EpiIntestinal™
  • EpiVaginal™
Tissue Models

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MatTek is a part of BICO. Our products aim to reduce the organ shortage and speed up drug development by providing accessible life science solutions that combine biology and technology, fundamentally shifting the global healthcare industry.
Read more at bico.com.

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  • About
  • Products
    • Tissue Models
      • EpiAirway
      • EpiAlveolar
      • EpiCorneal
      • EpiDerm
      • EpiDermFT
      • EpiGingival
      • EpiIntestinal
      • EpiOcular
      • EpiOral
      • EpiNasal
      • EpiVaginal
      • MelanoDerm
      • Melanoma
      • Psoriasis
      • Back
    • Primary Cells & Media
      • Primary Human Airway Cells & Media
      • Primary Human Corneal Cells & Media
      • Primary Human Dermal Cells & Media
      • Gingival
      • Intestinal
      • Ocular
      • Oral
      • Vaginal
      • Back
    • Cultureware
      • Glass Bottom Dishes
      • Multi-Well Plates
      • PermaCell Cell Culture Inserts
      • Back
    • Back
  • Applications
    • Dermal
      • Skin Irritation (OECD TG 439)
      • Skin Corrosion (OECD TG 431)
      • Anti-Aging
      • Skin Brightening
      • Anti-Psoriasis Drug Screening
      • Drug Delivery (Intestinal)
      • Genotoxicity
      • Phototoxicity (OECD TG 498)
      • Pigmentation Studies
      • Skin Hydration
      • Tumor Invasion
      • Anti-Melanoma Drug Screening
      • Back
    • Immune Cell
      • Allergenicity Testing
      • Microbial Infection
      • Basic DC Research
      • Back
    • Ocular
    • Respiratory
      • Respiratory Infection
      • Drug Delivery (Oral Mucosal)
      • Inhalation Toxicology
      • Inflammation and Fibrosis
      • Back
    • Oral Mucosal
      • Absorption
      • Oral Candidiasis
      • Drug Delivery
      • Back
    • Intestinal
      • Epithelial Restitution
      • Intestinal Fibrosis
      • Drug Metabolism
      • Dermal Drug Delivery
      • Inflammation
      • Back
    • Back
  • References
  • News
  • Store