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MatTek Corporation
200 Homer Avenue
Ashland, MA  01721
508-881-6771
FAX:  508-879-1532
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Data Sheet Specification Sheet Technical References
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MelanoDerm Technical References

471. SOX9 IS A KEY PLAYER IN ULTRAVIOLET B-INDUCED MELANOCYTE DIFFERENTIATION AND PIGMENTATION.

Passeron1, T., Valencia1, J.C., Bertolotto2, C., Hoashi1, T., Le Pape1, E., Takahashi1, K., Ballotti2, R., and Hearing1, V.J. 1 1Pigment Cell Biology Section, Laboratory of Cell Biology, National Cancer Institute, National...[more]

Category: Technical References, MelanoDerm

473. HUMAN SKIN RESPONSES TO UV RADIATION: PIGMENT IN THE UPPER EPIDERMIS PROTECTS AGAINST DNA DAMAGE IN THE LOWER EPIDERMIS AND FACILITATES APOPTOSIS.

Yamaguchi1, Y., Takahashi1, K., Zmudzka2, B.Z., Kornhauser3, A., Miller2, S.A., Tadokoro1, T., Berens1, W., Beer2, J.Z., and Hearing1, V.J. 1Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health,...[more]

Category: Technical References, MelanoDerm

474. INHIBITORY EFFECTS OF A NOVEL ASCORBIC DERIVATIVE, DISODIUM ISOSTEARYL 2-O-L-ASCORBYL PHOSPHATE ON MELANOGENESIS.

Matsuda1, S., Shibayama1,2, H., Hisama1, M., Ohtsuki2, M., and Iwaki3, M.1Central Research Center, Toyo Beauty Co., Ltd.; 3-13-8 Higashinakamoto, Higashinari-ku, Osaka 537-0021, Japan: 2Department of Dermatorogy, Jichi Medical...[more]

Category: Technical References, MelanoDerm

476. A COMPARISON OF TWO 4% HYDROQUINONE PRODUCTS ON MELANOCYTE MORPHOLOGY.

Dong, K.K., Canning, M.T., Smiles, K.A., and Yarosh, D.B. AGI Dermatics, Freeport, NY 11520. J. Am. Acad. Dermatol., P1022, February 2007 Summary: This study by scientists at AGI Dermatics demonstrated how MatTek's...[more]

Category: Technical References, MelanoDerm

490. QUERCETIN-INDUCED MELANOGENESIS IN A RECONSTITUTED THREE-DIMENSIONAL HUMAN EPIDERMAL MODEL.

Takeyama1, R., Takekoshi2, S., Nagata2, H., Osamura2, R.Y., & Kawana1, S. 1Department of Dermatology, Nippon Medical School, Sendagi 1-1-5, Bunkyou-ku Tokyo 113-8603, Japan. 2Department of Pathology, Tokai University...[more]

Category: Technical References, MelanoDerm

497. FORSKOLIN PROTECTS KERATINOCYTES FROM UVB-INDUCED APOPTOSIS AND INCREASES DNA REPAIR INDEPENDENT OF ITS EFFECTS ON MELANOGENESIS.

Passeron, T., Namiki, T., Passeron, H.J., Le Pape, E. and Hearing, V.J. Pigment Cell Biology Section, Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA. J. of Invest....[more]

Category: Technical References, MelanoDerm

500. IDENTIFICATION OF QUINOLINES THAT INHIBIT MELANOGENESIS BY ALTERING TYROSINASE FAMILY TRAFFICKING.

Ni-Komatsu, L., Tong, C., Chen, G., Brindzei, N., and Orlow, S.J. The Ronald O. Perelman Department of Dermatology and the Department of Cell Biology, New York University School of Medicine, New York, New York (L.N.-K.,...[more]

Category: Technical References, MelanoDerm

504. 1-(2,4-DIHYDROXYPHENYL)-3-(2,4-DIMETHOXY-3-METHYL-PHENYL)PROPANE, A NOVEL TYROSINASE INHIBITOR WITH STRONG DEPIGMENTING EFFECTS.

Nesterov1, A., Zhao1, J., Minter2, D., Hertel1, C., Ma1, W., Abeysinghe1, P., Hong1, M., and Jia1, Q. 1Unigen Pharmaceuticals, Inc.; 2660 Willamette Drive NE, Lacey, WA 98516, U.S.A.: and 2Chemistry Department, Texas...[more]

Category: Technical References, MelanoDerm

522. A LOTION CONTAINING UNDECYLENOYL PHENYLALANINE AND ERGOTHIONEINE REDUCES MELANIN LEVELS WITHOUT AFFECTING TISSUE VIABILITY IN ARTIFICIAL SKIN CONSTRUCTS.

Dong, K., Yarosh, D., Smiles, K., and Markova, N. AGI Dermatics, Freeport, NY, US. J Am Acad Dermatol, March 2009. Summary: This study by scientists at AGI Dermatics demonstrated that MatTek's MelanoDerm in vitro human...[more]

Category: Technical References, MelanoDerm

558. THE MATTEK STORY - HOW THE THREE Rs PRINCIPLES LED TO 3-D TISSUE SUCCESS!

Sheasgreen, J., Klausner, M., Kandárová, H., and Ingalls, D. MatTek Corporation, Ashland, MA, USA. ATLA, 37, 611–622, (2009). Summary: FRAME, the UK-based Fund for the Replacement of Animals in Medical Experiments, asked MatTek...[more]

Category: Technical References, DendriticCells, EpiAirway, EpiAirwayFT, EpiDerm, EpiDerm-201, EpiDermFT, EpiOcular, EpiOral, EpiVaginal

598. A ZN(LL)-GLYCINE COMPLEX SUPPRESSES UVB-INDUCED MELANIN PRODUCTION BY STIMULATING METALLOTHIONEIN EXPRESSION.

Ochiai1, Y., Kaburagi1, S., Okano1, Y., Masaki1, H., Ichihashi2, M., Funasaka3, Y. and Sakurai4, H. 1Cosmos Technical Center Co., Ltd, Tokyo, Japan. 2Sun Clinic, Sun Care Institute, Osaka, Japan. 3Division of Dermatology,...[more]

Category: Technical References, EpiDerm, MelanoDerm

601. INHIBITORY EFFECTS OF Á-ARBUTIN ON MELANIN SYNTHESIS IN CULTURED HUMAN MELANOMA CELLS AND A THREE-DIMENSIONAL HUMAN SKIN MODEL.

Sugimoto1, K., Nishimura1, T., Nomura1,K., Sugimoto2, K., and Kurikia1, T. 1Biochemical Research Laboratory, Ezaki Glico Co., Ltd.; Osaka, Japan and 2Laboratory of Applied Molecular Biology, Division of Applied...[more]

Category: Technical References, MelanoDerm

620. THE FIBROBLAST-DERIVED PARACRINE FACTOR NEUREGULIN-1 HAS A NOVEL ROLE IN REGULATING THE CONSTITUTIVE COLOR AND MELANOCYTE FUNCTION IN HUMAN SKIN.

Choi1, W., Wolber2, R., Gerwat2, W., Mann2, T., Batzer2, J., Smuda2, C., Liu3, H., Kolbe2,L. and Hearing1, V.J. 1Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA...[more]

Category: Technical References, MelanoDerm

637. INSPECTION OF SKIN HEMODYNAMICS WITH HYPERSPECTRAL CAMERA.

Nagaoka1, T., Eikje2, N.S., Nakamura3, A., Aizawa3, K., Kiyohara4, Y., Ichikawa5, F., Yamazaki6, T., Doi, M., Nakamura6, K., Otsubo, S., Sota2, T. 1Shizuoka Cancer Research Institute, Japan; 2Dept. of Electrical Engineering and...[more]

Category: MelanoDerm

668. RECONSTRUCTED HUMAN SKIN MODEL TO STUDY MELANOMA AT DIFFERENT STAGES OF PROGRESSION.

 Kaluzhny, Y., Ayehunie, S., and Klausner, M. MatTek Corporation, Ashland, MA, USA. Presented at Soc. Invest. Derma., Meeting, May 2011.  J. of Invest. Derma., (131, Suppl. 1, Abstract 771 (2011). The incidence of...[more]

Category: MelanoDerm

694. FGF2 REGULATES MELANOCYTES VIABILITY THROUGH THE STAT3-TRANSACTIVATED PAX3 TRANSCRIPTION.

Dong1,2,6, L., Li1,6, Y., Caol, J., Liu1, F. Pier1,7, E., Chen1, E., Xu3, Z., Chen4, C., Wang5, R-a., Cui1, R.  1Department of Dermatology, Boston University School of Medicine, 609 Albany Street, Boston, MA 02118, USA;...[more]

Category: MelanoDerm

695. HYPERPIGMENTATION IN HUMAN SOLAR LENTIGO IS PROMOTED BY HEPARANASE-INDUCED LOSS OF HEPARAN SULFATE CHAINS AT THE DERMAL–EPIDERMAL JUNCTION

Iriyama, S., Ono, T., Aoki, H., Amano, S. Shiseido Research Center, 2-2-1 Hayabuchi, Tsuzuki-ku, Yokohama 224-8558, Japan Journal of Dermatological Science, 64, 223–228, (2011). Summary: Background: Skin pigmentation induced by...[more]

Category: MelanoDerm

698. EBSELEN IS A NEW SKIN DEPIGMENTING AGENT THAT INHIBITS MELANIN BIOSYNTHESIS AND MELANOSOMAL TRANSFER.

 Kasraee1, B., Nikolic1, D.S., Salomon1, D., Carraux1, P., Fontao1, L., Piguet1, V., Omrani2, G.R., Sorg1,3,O., and Saurat1,3, J-H. 1Department of Dermatology, Geneva University Hospital, Geneva, Switzerland; 2Endocrinology...[more]

Category: MelanoDerm


Dendritic (Langerhans) Cells
EpiAirway Normal Human Airway Tissue Model
EpiDerm Reconstructed Human Epidermis (RhE) Tissue Model
EpiDerm-201 Under-developed Skin Model
EpiDermFT™ Skin Model
EpiOcular Normal Human Corneal Tissue Model
EpiOral Normal Human Buccal, EpiGingival Normal Human Gum Tissue Models
EpiVaginal Normal Human Ecto-Cervical Vaginal Tissue Model
MelanoDerm Normal Human Skin Model with Melanocytes
Melanoma Skin Model
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