EpiOcularTM Technical References
457. |
NEW! |
EXPANDED UTIILZATION OF THE EPIOCULAR™ HUMAN TISSUE MODEL FOR OCULAR IRRITATION TESTING.
Kaluzhny, Y., Thornton, L., Hayden, P., Kandarova, H., and Klausner, M.
MatTek Corporation, Ashland, MA, USA.
Presented at 6th World Congress on Alternatives and Animal Use, Tokyo, August (2007).
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454. |
NEW! |
EXPERIENCES IN THE DEVELOPMENT AND UTILIZATION OF AN IN VITRO SAFETY TESTING PROGRAM FOR HAIR CONDITIONERS.
Vavilikolanu1, P., Lazaro1, C., Mun2, G., Hilberer2, A., Hyder2, M., Raabe2, H., and Curren2, R.
1Alberto-Culver Company, Melrose Park, IL, USA, 2Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA.
Presented at the 6th World Congress on Alternatives and Animal Use in the Life Sciences, Tokyo, Japan August 21-25, (2007).
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442. |
NEW! |
REGULATORY REQUIREMENTS FOR IN VITRO SYSTEMS TO MEET PERFORMANCE STANDARDS OVER TIME AS WELL AS DURING VALIDATION.
Klausner, M., Kubilus, J., Ayehunie, S., Hayden, P., Chua, G., Sheasgreen, J.
MatTek Corporation, Ashland, MA 01721.
Society of Toxicology 46th Annual Meeting, Charlotte, NC, Abstract 1524, (2007).
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436. |
NEW! |
USE OF THE EPIOCULAR ASSAY FOR PRECLINICAL QUALIFICATION OF FORMULAS FOR HUMAN CLINICAL STUDIES.
Niranjan, P., Dang, A.H., January, B.G., Gomez, C., Harbell, J.W.
Mary Kay Inc., Dallas, TX, USA.
Society of Toxicology 46th Annual Meeting, Charlotte, NC, (2007).
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402. |
NEW! |
DEVELOPMENT OF IMPROVED EPIOCULAR™ TEST PROTOCOLS FOR SCREENING OF SEVERE OCULAR IRRITANTS.
Jackson, G.R. Jr., Hayden, P.J., Kubilus, J., Kaluzhny, Y., Klausner, M.
MatTek Corporation, Ashland, MA, USA.
Presented at the 45th Society of Toxicology Meeting, San Diego CA, March 5-9, (2006)
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392. |
NEW! |
USE OF HUMAN SKIN EQUIVALENT CULTURES FOR COSMETIC BENEFIT SCREENING.
McPhail1, S., Messersmith1, E., Thomas1, R., Mullins1, L., Osborne1, R., Grove2, G.
1Procter and Gamble, Miami Valley Innovation Center, Beauty Technology Division, 11810 East Miami River Road Cincinnati, OH 45252. 2CyberDERM, 700 Parkway, Broomall, PA 19008.
Presented at the American Academy of Dermatology, New Orleans, LA, February 19, (2005).
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385. |
NEW! |
USE OF EPIDERM FULL THICKNESS TISSUE FOR ANTI-AGING STUDIES.
Gruber, V., et al.
Arch Personal Care Products L.P., South Plainfield, NJ and Bio-Innovation Laboratories, McKinney, TX.
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377. |
NEW! |
PROGRAM TO REDUCE ANIMAL TESTING FOR EPA REGISTRATIONS OF ANTIMICROBIAL PRODUCTS.
Sauers1, L., Acuff1, K., Marsman1, D., Vedula2, U., Cuellar2, N., Curren3, R., Harbell3, J., Quinn4, P.
1The Proctor & Gamble Co., Cincinnati, Ohio, USA; 2S.C. Johnson, Racine, Wisconsin, USA; 3Institute for In Vitro Sciences, Gaithersburg, Maryland, USA; 4The Accord Group, Washington, DC, USA.
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374. |
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IN VITRO METHODS FOR ASSESSING OCULAR IRRITANCY OF COSMETICS.
Richert, S., Schrader, A., Schrader, K.
Institute Dr. Schrader Creachem GmbH, Holzminden, Germany.
Presented at 5th World Congress, Berlin, Germany, August 21-25, (2005).
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356. |
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EPIOCULAR™ HUMAN CELL CONSTRUCT: TISSUE VIABILITY AND HISTOLOGICAL CHANGES FOLLOWING EXPOSURE TO SURFACTANTS.
Blazka1, M., Diaco2, M., Harbell2, J., Raabe2, H., Sizemore2, A., Wilt2, N., Bagley1, D.
1Colgate-Palmolive Co., Piscataway, NJ, USA; 2Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA.
Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. The Toxicologist, 84, (1), Abstract # 2001, 409, (2005).
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354. |
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HIGH-THROUGHPUT IN VITRO MODELS OF HUMAN EPIDERMIS AND OCULAR EPITHELIUM FOR PRECLINICAL SAFETY AND EFFICACY TESTING OF CONSUMER PRODUCTS AND PHARMACEUTICALS.
Jackson, G., Kubilus, J., Klausner, M., Sheasgreen, J., Hayden, P.
MatTek Corporation, Ashland, MA.
Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. The Toxicologist, 84, (1), Abstract # 2003, 409-410, (2005).
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353. |
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LONG TERM REPRODUCIBILITY OF EPIOCULAR™, A THREE-DIMENSIONAL TISSUE CULTURE MODEL OF THE HUMAN CORNEAL EPITHELIUM.
Klausner, M., Sheasgreen, J., Kubilus, J., Hayden, P.
MatTek Corporation, Ashland, MA.
Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. The Toxicologist, 84, (1), Abstract # 2002, 409, (2005).
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350. |
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QUALITY ASSURANCE FOR IN VITRO ALTERNATIVE TEST METHODS: QUALITY CONTROL ISSUES IN TEST KIT PRODUCTION.
Rispin1, A., Harbell2, J.W., Klausner3, M., Jordan4, F.T., Coecke5, S., Gupta6, K., Stitzel7, K.
1US Environmental Protection Agency, Office of Pesticide Programs (7506C), Washington, DC, USA; 2Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA; 3MatTek Corporation, Ashland, MA, USA; 4Charles River Endosafe Corporation, Wilmington, MA, USA; 5European Centre for the Validation of Alternative Methods, Institute for Health and Consumer Protection, European Commission Joint Research Centre, Ispra, Italy; 6US Consumer Product Safety Commission, Bethesda, MD, USA; 7Consultant, West Chester, OH, USA.
ATLA, 32, (1), 725-729, (2004).
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348. |
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COMPARATIVE ASSESSMENT OF TWO EYE AREA COSMETIC FORMULATIONS THROUGH EVALUATION OF ALTERNATIVE EYE IRRITATION METHODS RELATIVE TO ENDPOINTS MEASURED IN A HUMAN CLINICAL SUB-ACUTE STUDY DESIGN.
Burdick2, J.D., Gao3, Y., Kanengiser3, B., Merrill1, J.C., Harbell1, J.W.
1Institute for In Vitro Sciences, Inc., Gaithersburg, MD; 2Bath & Body Works, Reynoldsburg, OH; 3Clinical Research Laboratories, Inc., Piscataway, NJ.
Presented at Society of Toxicology Annual Meeting, Salt Lake City, Utah, March 9-13, (2003).
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333. |
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DI-PPG-2-MYRETH-10 ADIPATE REDUCES IRRITATION AND INFLAMMATION CAUSED BY COSMETIC PRODUCTS.
Joseph¹, L.B., DeShields², L., Pereira¹, A.G., Stoudemayer, M.J., Langley¹, N.A.
¹Croda Inc., Edison, NJ 08837, ²S.K.I.N. Inc., Conshohocken, PA 19428.
J. Invest. Dermatol., 122, (3), A7, Abstract #40, (2004).
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304. |
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STUDIES OF BYSTANDER EFFECTS IN ARTIFICIAL HUMAN 3D TISSUE SYSTEMS USING A MICROBEAM IRRADIATION.
Belyakov, O.V., Hall, E.J., Marino, S.A., Randers-Pehrson, G., Brenner, D.J.
Columbia University, Irvington, NY. Center for Radiological Research
(Annual Report), (2002).
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299. |
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ASSESSMENT OF HUMAN SKIN IRRITATION: VALIDATION OF IN VITRO MODELS.
MatTek Scientific, Marketing Staff.
MatTek Corporation, Ashland, MA (USA).
May 2003.
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287. |
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EVALUATION OF MTT METABOLISM AS A MEANINGFUL INDICATOR OF VIABILTY IN HUMAN CORNEAL EPITHELIAL TISSUE MODELS.
Hines, M.D., Gettings, S.D. and Jones, B.C.
Avon Products, Inc., Suffern, NY USA.
Presented at 2003 Society of Toxicology Meeting.
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285. |
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EVALUATING THE OCULAR IRRITATION POTENTIAL OF 54 TEST ARTICLES USING THE EPIOCULAR™ HUMAN TISSUE CONSTRUCT MODEL (OCL-200).
ME Blazka1, JW Harbell2, M Klausner3, J Merrill2, J Kubilus3, C Kloos1 and DM Bagley1.
1Colgate-Palmolive Co., Piscataway, NJ, USA. 2Institute for In Vitro Sciences, Gaithersburg, MD, USA. 3MatTek Corp., Ashland, MA, USA.
Presented at 2003 Society of Toxicology Meeting.
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274. |
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BARRIER FUNCTION COMPARISON BETWEEN IN VITRO SKIN, ORAL (BUCCAL), AND OCULAR TISSUE MODELS - IMPLICATIONS FOR DRUG DELIVERY STUDIES.
Klausner1, M., Kubilus1, J., Song2, Y., Michniak2, B.,
1Department of Research and Development, MatTek, Ashland, MA, 2Department of Pharmacology and Physiology, UMDNJ-NJMS, Newark, NJ.
Presented at the American Association of Pharmaceutical Scientists Meeting, November (2002).
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259. |
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ASSESSMENT OF OCULAR IRRITATION RANGES OF MARKET-LEADING COSMETIC AND PERSONAL-CARE PRODUCTS USING AN IN VITRO TISSUE EQUIVALENT.
McCain, N.E., Binetti, R.R., Gettings, S.D., Jones, B.C.
Cell Biology & In Vitro Toxicology, Avon Products, Inc., Suffern, NY.
The Toxicologist, 66 (1-S), 243, Soc. of Toxicol. (Reston, VA), Abstract #1191, (2002).
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253. |
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THE EFFECTS OF KNOWN EYE IRRITANTS ON THE SKINETHIC™ AND EPIOCULAR™ MODELS OF CORNEAL EPITHELIUM.
Jones, P., King, A. and Fentem, J.
Safety and Environmental Assurance Centre., Unilever Colworth Laboratory, Colworth House, Sharnbrook, Bedford, MK44 1LQ, UK.
Presented at the 43rd International Conference of the European Tissue Culture Society, Granada, Spain, September 30-October 3, (2001).
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248. |
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COMPARATIVE EVALUATION OF FIVE IN VITRO TESTS FOR ASSESSING THE EYE IRRITATION POTENTIAL OF HAIR-CARE PRODUCTS.
Jones1, P.A., Budynsky2, E., Cooper1, K.J., Decker2, D., Griffiths1, H.A., and Fentem1, J.H.
1Safety & Environmental Assurance Centre (SEAC), Unilever Colworth Laboratory, Sharnbrook, Bedfordshire MK44 1LQ, UK; 2Unilever Home & Personal Care, 3100 Golf Road, Rolling Meadows, IL 60008, USA.
ATLA 29, 669-692, (2001).
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223. |
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HUMANE ENDPOINTS AND ACUTE TOXICITY TESTING.
Sass, N.
Alabama Department of Public Health, Montgomery, Alabama, USA.
ILAR Journal, 41(2), 14-23, (2000).
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191. |
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THE EPIOCULAR TISSUE MODEL: IN VIVO VERSUS IN VITRO DRAIZE SCORES FOR CONSUMER PRODUCTS.
Klausner1, M., Osborn1, M., Bellavance1, K., Breyfogle1, B., Kubilus1, J., Cerven2, D.R., DeGeorge2, G.
1MatTek Corp., Ashland, MA, 2MB Research Laboratories, Spinnerstown, PA
Toxicological Sciences, 54, (1), 188 Abstr. #884 (2000).
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190. |
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COLGATE-PALMOLIVE'S PROGRAM - VALIDATE THE EPlOCULAR™ HUMAN TISSUE CONSTRUCT MODEL (OCL200).
Blazka1, M.E., Harbell2, J.W., Klausner3, M., Raabe2, H., Kubilus3, J., Hsia4, F., Minerath5, B., Bagley1, D.M.
1Colgate-Palmolive Co., Piscataway NJ, 2Institute for In Vitro Sciences, Gaithersburg, MD, 3MatTek Corp., Ashland, MA, 43M Co., St. Paul, MN, 5Kimberly Clark, Neenah, WI.
Toxicological Sciences, 54, (1), 188, Abstr. #884 (2000).
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183. |
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THE APPLICATION OF REFERENCE STANDARDS IN THE PREVALIDATION AND VALIDATION OF IN VITRO TESTS FOR EYE IRRITATION.
Brantom, P., Fentem1, J., Balls2, M., Cassidy3, S.
BIBRA International, Woodmansterne Road, Carshalton, Surrey SM5 4DS, UK, 1SEAC Toxicology, Unilever Research, Colworth, Sharnbrook, Bedfordshire MK44 1LQ, UK, 2ECVAM, Institute for Health & Consumer Protection, European Commission Joint Research Centre, 21020 Ispra (Va) Italy, 3Dow Corning, Rue General de Gaulle 62, 1310 la Hulpe, Belgium.
ATLA, 27, 332, (1999).
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178. |
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COLGATE-PALMOLIVE'S PROGRAMME TO VALIDATE THE EPIOCULAR™ HUMAN TISSUE CONSTRUCT MODEL (OCL-200).
Blazka, M.E., Harbell1, J.W., Klausner2, M., Raabe1, H., Kubilus2, J., Hsia3, F., Minerath4, B., Bagley, D.M.
Colgate-Palmolive, Piscataway, NJ, USA, 1Institute for In Vitro Sciences, Gaithersburg, MD, USA, 2MatTek, Corp. Ashland, MA, USA, 33M, St Paul, MN, USA, 4Kimberly Clark, Neenah, WI, USA.
ATLA, 27, 331, (1999).
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176. |
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THE EPIOCULAR™ PREDICTION MODEL: A REPRODUCIBLE IN VITRO MEANS OF ASSESSING OCULAR IRRITANCY POTENTIAL.
Klausner1, M., Sheasgreen1, J., Breyfogle1, B., Sennott1, H., Liebsch2, M., Kubilus1, J.
1MatTek Corp., Ashland, MA 01721, USA, 2ZEBET, 12277 Berlin, Germany.
ATLA, 27, (special issue), 299, (1999). Published in Alternative Toxicological Methods. Editors H. Salem, S.A. Katz. CRC Press LLC, Boca Raton, FL, USA, 229-247 (2003).
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167. |
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THE EPIOCULAR™ PREDICTION MODEL - A REPRODUCIBLE IN VITRO MEANS OF ASSESSING OCULAR IRRITANCY POTENTIAL.
Klausner, M., Sennott, H.A., Breyfogle, B., Makwana, A., Kubilus, J.
MatTek Corp., Ashland, MA, USA.
The Toxicologist, 48 (1-S), 336, Soc. of Toxicology (Reston, VA), Abstract #1583, (1999).
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166. |
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FURTHER EVALUATION OF THE EPIDERM™ AND EPIOCULAR™ IN VITRO IRRITATION MODELS.
Nicastro, S.C., Ladics, G.S.
The DuPont Co., Haskell Laboratory for ToxicoIogy and Industrial Medicine, Newark, DE.
SOT 1999 Annual Meeting. The Toxicologist, 48 (1-S), 70, Soc. of Toxicology (Reston, VA), Abstract #360, (1999).
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159. |
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THE EYE IRRITATION TESTING OF THE ORGANIC SOLVENTS ON IN VITRO TEST USING 3-D CORNEAL MODEL.
Akaza, N., Kojima, H., Katada. T., Konishi, H.
Research Institute, Nippon Menard Cosmetic Co., Ltd.
Presented at 12th Annual Meeting of the Japanese Society for Alternatives to Animal Experiments, Sendai, Japan, November 18-19, (1998).
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151. |
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MATTEK'S TISSUE MODELS: NEW DEVELOPMENTS.
Klausner, M.
MatTek Corp., Ashland, MA 01721.
Presented at International Business Conference, "Latest In Vitro Testing Methods for Skin Care, Cosmetics, and Household Products," Washington, D.C., (1997).
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147. |
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THE EPIOCULAR PREDICTION MODEL: AN ACCURATE, REPRODUCIBLE IN VITRO MEANS OF ASSESSING OCULAR IRRITANCY POTENTIAL.
Klausner, M., Sennott, H.A., Breyfogle, B., Makwana, A., Kubilus, J.
MatTek Corp., Ashland, MA.
Toxicology In Vitro, 12, (4), 455-461 (1998).
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146. |
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EVALUATION OF THE EPIOCULAR™ TISSUE MODEL AS AN ALTERNATIVE TO THE DRAIZE EYE IRRITATION TEST.
1Stern, M., 2Klausner, M., 1Alvarado, R., 1Renskers, K., 1Dickens, M.
1Avon Products, Inc., Suffern, NY, 2MatTek Corp., Ashland, MA.
Toxicology In Vitro, 12, 455-461, (1998).
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142. |
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EPIOCULAR™ PREDICTION MODEL. A REPRODUCIBLE IN VITRO TISSUE CULTURE MEANS OF PREDICTING DRAIZE SCORES.
Kubilus, J., Sennott, H., Makwana, A., Klausner, M.
MatTek Corp., Ashland, MA.
The Toxicologist, 36 (1), 44, Soc. of Toxicol. (Reston, VA), Abstract #222, (1997).
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141. |
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DEMONSTRATING THE OCULAR SAFETY OF AN EYE COSMETIC PRODUCT USING ALTERNATIVES TO ANIMAL EYE IRRITATION TESTS.
Ghassemi1, A., Osborne1, R., Kohrman1, K. A., Roddy1, M. T., Harbell2, J.W., Kanengiser3, B.E.
1The Procter & Gamble Company, Hunt Valley, MD and Cincinnati, OH, 2Microbiological Associates, Inc. Rockville, MD, 3Clinical Research Laboratories, Inc., Piscataway, NJ. Sponsored by L.D. Lehman-McKeeman.
The Toxicologist, 36 (1), 42, Soc. of Toxicol. (Reston, VA), Abstract #221, (1997).
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139. |
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PREDICTION OF OCULAR IRRITATION POTENTIAL OF AIR CARE PRODUCTS USING IN VITRO TOPICAL APPLICATION ASSAYS.
Manderfield1, C.E., Swanson1, J.E., Kennedy1, O., Lee2, M.K., Bauernschub2, M.A., Harbell2, J.W.
1S. C. Johnson & Son, Inc., Racine, WI, 2Microbiological Associates, Inc., Rockville, MD. Sponsored by R. D. Curren.
The Toxicologist, 36 (1), 44, Soc. of Toxicol. (Reston, VA), Abstract #223, (1997).
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135. |
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REPRODUCIBILITY AND CORRELATION OF EPIOCULAR™, A THREE-DIMENSIONAL TISSUE CULTURE MODEL OF HUMAN CORNEAL EPITHELIUM.
Sheasgreen, J., Kubilus, J., Sennott, H., Ogle, P., Klausner, M.
MatTek Corp., Ashland, MA.
ATLA, 24, Special Issue, 284, Abstract #284, (1996).
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130. |
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A COMPARISON OF IN VITRO EYE IRRITATION TEST DATA FOR ORGANOSILICON COMPOUNDS.
Cassidy, S. L., Stanton, E.
Dow Corning Toxicology Laboratory, Midland, MI, USA.
Society of Toxicology Annual Meeting, Anaheim, CA. The Toxicologist, 30 (1), 123, Soc. of Toxicol. (Reston, VA), Abstract # 629, (1996).
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129. |
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REPRODUCIBILITY AND CORRELATION OF EPIOCULAR™, A THREE-DIMENSIONAL TISSUE CULTURE MODEL OF THE HUMAN CORNEAL EPITHELIUM.
Sheasgreen, J., Kubilus, J., Sennott, H., Ogle, P., Klausner, M.
MatTek Corp., Ashland, MA.
The Toxicologist, 30 (1), 128, Soc. of Toxicol. (Reston, VA), Abstract# 653, (1996).
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115. |
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INITIAL CHARACTERIZATION OF A NEW MODEL FOR OCULAR IRRITANCY TESTING.
Ricker, H.A., Neal, P.J., Kubilus, J., Klausner, M.
MatTek Corp., Ashland, MA.
In Vitro Cell & Devel. Biol., 30A(3), Abstract #T-1004, June (1994).
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