EpiDermTM Technical References
559. |
NEW! |
IN VITRO SKIN IRRITATION TESTING: IMPROVING THE SENSITIVITY OF THE EPIDERM SKIN IRRITATION TEST PROTOCOL.
Kandárová, H., Hayden, P., Klausner, M., Kubilus, J., Kearney, P., and Sheasgreen, J.
MatTek Corporation, Ashland, MA, USA.
ATLA, 37, 671–689, 2009.
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558. |
NEW! |
THE MATTEK STORY — HOW THE THREE Rs PRINCIPLES LED TO 3-D TISSUE SUCCESS!
Sheasgreen, J., Klausner, M., Kandárová, H., and Ingalls, D.
MatTek Corporation, Ashland, MA, USA.
ATLA, 37, 611–622, (2009).
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557. |
NEW! |
INFLAMMATORY ACTIVITY OF PARTHENOLIDE-DEPLETED FEVERFEW (TANACETUM PARTHENIUM).
Sur1, R., Martin1, K., Liebel1, F., Lyte1, P., Shapiro1, S., and Southall2, M.
1Preclinical Pharmacology, Johnson and Johnson Skin Research Center, CPPW, a unit of Johnson & Johnson Consumer Companies, Inc., Skillman, NJ. 2Johnson & Johnson Consumer & Personal Products Worldwide, Skillman, NJ.
Inflammopharmacology, 17, 42-49 (2009).
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556. |
NEW! |
ASSESSMENT OF DERMAL TOXICITY OF NANOSILICA USING CULTURED KERATINOCYTES, A HUMAN SKIN EQUIVALENT MODEL AND AN IN VIVO MODEL.
Park1, Y-H., Kim1, J.N., Jeong1, S.H., Choi1, J.E., Lee2, S-H., Choi1, B.H., Lee3, J.P., Sohn3, K.H., Park3, K.L., Kim2, M-K., Son1, S.W.
1Laboratory of Cell Signaling and Nanomedicine, Department of Dermatology and Division of Brain Korea 21 Project for Biomedical Science, Korea University College of Medicine, Seoul, South Korea. 2Department of Biochemistry & Molecular Biology, Korea University College of Medicine, Seoul, South Korea. 3National Institute of Toxicological Research, Seoul, South Korea.
Toxicology, 267, 178–181, (2010).
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554. |
NEW! |
REGULATION OF APOPTOSIS BY P53 IN UV-IRRADIATED HUMAN EPIDERMIS, PSORIATIC PLAQUES AND SENESCENT KERATINOCYTES.
Qin1,2, J-Z., Chaturvedi1,2, V., Denning1, M.F., Bacon1, P., Panella1, J., Choubey2, D., and Nickoloff1, B.J.
1Department of Pathology, Loyola University Medical Center, Illinois, USA; 2Department of Radiation Oncology, Loyola University Medical Center, Illinois, USA.
Oncogene, 21, 2991-3002, (2002).
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550. |
NEW! |
IMPROVING GENOTOXICITY TESTING: COMET ASSAY WITH 3D SKIN MODELS.
Pfuhler7, S., Krul4, C., Ouédraogo5, G., Reus4, A., Reisinger1, K., Zeller7, A., Carmichael8, P., Corvi2, R., Hewitt3, N., Aardema9, M., Diembeck10, W., Fautz11, R, Harvey12, J., Latil13, A., Marrec-Fairley6, M.
1Henkel AG & Co KgaA, Duesseldorf, Germany; 2EC/JRC/ECVAM, Ispra, Italy; 3Erzhausen, Germany; 4TNO Quality of Life, Zeist, The Netherlands; 5L’Oréal, Aulnay-sous-Bois, France; 6COLIPA, Brussels, Belgium; 7Procter & Gamble - Cosmital SA, Marly, Switzerland ; 8Unilever, Sharnbrook, UK; 9The Procter & Gamble Co., Cincinnati, OH, USA; 10Beiersdorf AG, Hamburg, Germany; 11KPSS-Kao Professional Salon Services, Darmstadt, Germany; 12GSK, Ware, UK; 13Pierre Fabre, France.
Presented at 7th World Congress on Alternatives to Animal Testing, Rome (2009).
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548. |
NEW! |
VISUALIZATION AND CHARACTERIZATION OF UVB-INDUCED REACTIVE OXYGEN SPECIES IN A HUMAN SKIN EQUIVALENT MODEL.
Hakozaki1, T., Date1, A., Yoshii1, T., Toyokuni2, S., Yasui3, H., Sakurai3, H.
1Kobe Technical Center 7F, Procter & Gamble Japan, 2Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan. 3Department of Analytical and Biorganic Chemistry, Kyoto Pharmaceutical University, Kyoto, Japan.
Arch Dermatol Res, 300, (Suppl 1):S51–S56 (2008).
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545. |
NEW! |
COLIPA VALIDATION OF THE RECONSTRUCTED HUMAN SKIN MICRONUCLEUS ASSAY (RSMN): A NOVEL MICRONUCLEUS ASSAY IN A 3D HUMAN SKIN MODEL.
Aardema1, M., Khambatta1, Z., Barnett1, B., Reisinger, K., Ouedraogo3, G., Faquet3, B., Ginestet3, A.C., Mun4, G., Dahl4, E., Curren4, R., Carmichael5, P., Diembeck6, W., Fautz7, R., Harvey8, J., Hewitt9, N., Latil10, A., Pfuhler11, S., Marrec-Fairley12, M.
1The Procter & Gamble Co., Cincinnati, OH, USA; 2Henkel AG & Co KGaA, Duesseldorf, Germany; 3L’Oreal Life Sciences Research, Aulnay sous Bois, France; 4Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA; 5Unilever, Sharnbrook UK; 6Beiersdorf AG, Hamburg, Germany; 7KPSS - Kao Professional Salon Services, Darmstadt, Germany; 8GSK, Ware, UK; 9Erzhausen, Germany; 10Pierre Fabre, Toulouse, France; 11The Procter & Gamble Co., Marly, Switzerland; 12COLIPA, Brussels, Belgium.
Presented at 7th World Congress on Alternatives to Animal Testing, Rome (2009).
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543. |
NEW! |
RETAINING CELL INTEGRITY DURING ORGANOTYPIC MODEL VIABILITY ASSAYS: ALTERNATIVES TO MTT.
Kavanagh1, C.R., Crawford1, L.J., Sawicka3, K.M., Simon1,2, S.R., and Roemer1,2, E.J.
Departments of 1Pathology, 2Biochemistry and Cell Biology and 3BioMedical Engineering, SUNY Stony Brook, Stony Brook, NY, 11794.
Presented at Society of In Vitro Biol. Meeting, Charleston, SC, June 2009.
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542. |
NEW! |
VALIDATING MTS AS AN ALTERNATIVE VIABILITY ASSAY TO MTT ON THE HUMAN 3-D TISSUE MODELS, EPIAIRWAY AND EPIDERM.
Kavanagh1, C.R., Crawford1, L.J., Simon1,2, S.R. and Roemer1,2, E.J.
Departments of 1Pathology, and 2Biochemistry and Cell Biology, SUNY Stony Brook, Stony Brook, NY, 11794.
Presented at Society of In Vitro Biol. Meeting, Charleston, SC, June 2009.
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541. |
NEW! |
REGULATION OF TIGHT JUNCTION PERMEABILITY BY SODIUM CAPRATE IN HUMAN KERATINOCYTES AND RECONSTRUCTED EPIDERMIS.
Kurasawa1, M., Kuroda1, S., Kida1, N., Murata2, M., Oba1, A., Yamamoto1, T., Sasaki2, H.
1Pola Chemical Industries Inc., 560 Kashio-cho, Totsuka-ku, Yokohama 244-0812, Japan. 2Department of Molecular Cell Biology, Institute of DNA Medicine, The Jikei University School of Medicine, 3-35-8 Nishishinbashi, Minato-ku, Tokyo 105-8461, Japan.
Biochem. Biophys. Res. Commun., 381, 171-175 (2009).
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539. |
NEW! |
ANTIOXIDANT CAPACITY OF 3D HUMAN SKIN EPIDERM MODEL: EFFECTS ON SKIN MOISTURIZERS.
Grazul-Bilska1,2, A.T., Bilski1,2, J.J., Redmer1,2, D.A., Reynolds1,2, L.P., Abdullah3,4, K.M. and Abdullah3,4, A.
1Department of Animal Sciences, 2Cell Biology Center, North Dakota State University, Fargo. 3Department of Surgery, School of Medicine, University of North Dakota, Grand Forks and 4Plastic Surgery Institute, Fargo, ND, USA.
Inter. J. of Cosmetic Science, 31, 201-208, (2009).
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537. |
NEW! |
ANALYSIS OF IONIZING RADIATION-INDUCED DNA DAMAGE AND REPAIR IN THREE-DIMENSIONAL HUMAN SKIN MODEL SYSTEM.
Su, Y., Meador, J.S., Geard, C.R., and Balajee, A.S.
Center for Radiological Research, Department of Radiation Oncology, College of Physicians and Surgeons, Columbia University Medical Center, New York, NY, USA.
Experimental Dermatology, 1600-1625, (2009).
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536. |
NEW! |
THE TRANSPORT PROFILE OF CYTOKINES IN EPIDERMAL EQUIVALENTS SUBJECTED TO MECHANICAL LOADING.
Cornelissen1, L.H., Bronneberg1, D., Bader1,2, D.L., Baaijens1, F.P.T., and Oomens1, C.W.J.
1Department of Biomedical Engineering, Laboratory for Biomechanics and Tissue Engineering, Eindhoven University of Technology, Building W-hoog 4.11, P.O. Box 513, 5600 MB Eindhoven, The Netherlands. 2School of Engineering and Material Science, Queen Mary, University of London, London, UK.
Annals of Biomedical Engineering, 37, 5, 1007–1018 (2009).
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533. |
NEW! |
EYE AND SKIN IRRITATION IN 3-D HUMAN TISSUE CONSTRUCTS USING MTT AND ATP ENDPOINTS.
Raabe2, H., Burdick1, J., Hanlon2, E., Hilberer2, A., Hyder2, M., Inglis2, H., Kong2, A., Majewski1, S., McNamara1, M., Mun2, G., Nash2, J., Wilt2, N.
1Beauty Avenues, Reynoldsburg, OH, USA. 2Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA.
VII World Congress on Alternatives & Animal Use in the life Sciences, Rome, Italy, Sept 1, 2009.
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531. |
NEW! |
ALTERNATIVE METHODS FOR PHOTOTOXICITY TEST USING RECONSTRUCTED HUMAN SKIN MODEL.
Sohn, S., Ju3, J.H., Son1, K.H., Lee3, J.P., Kim, J., Lim, C.H., Hong, S.K., Kwon, T.R., Chang, M., Kim2, D.S., Yoon3, H.S., Park2, K.L.
Toxicological Evaluation and Research Department, 1Pharmaceuticals and Medical Devices Research Department, 2Center for Drug Development Assistance, National Institute of Food and Drug Safety Evaluation, 3KFDA.
Altex, Vol 26, Spec. Issue, p. 136 (2009).
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528. |
NEW! |
AN IN VITRO SKIN IRRITATION TEST (SIT) USING THE EPIDERM RECONSTRUCTED HUMAN EPIDERMAL (RHE) MODEL. (VIDEO Protocol)
Kandarova, H., Hayden, P., Klausner, M., Kubilus, J., Sheasgreen, J.
MatTek Corp., Ashland, MA (USA).
JoVE. 29. http://www.jove.com/index/details.stp?id=1366, doi: 10.3791/1366 (2009).
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520. |
NEW! |
EFFECT OF SIZE AT THE NANOSCALE AND BILAYER RIGIDITY ON SKIN DIFFUSION OF LIPOSOMES.
Babu1, S., Fan1, C., Stepanskiy1, L., Uitto2, J., Papazoglou1, E.
1School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, Pennsylvania. 2Department of Dermatology and Cutaneous Biology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania.
Journal of Biomedical Materials Research, Part A (2008).
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517. |
NEW! |
DERMAL PENETRATION AND METABOLISM OF p-AMINOPHENOL AND p-PHENYLENEDIAMINE: APPLICATION OF THE EPIDERM HUMAN RECONSTRUCTED EPIDERMIS MODEL.
Hua, T., Baileya, R.E., Morralla, S.W., Aardemaa, M.J., Stanleyb, L.A., Skarec, J.A.
aThe Procter & Gamble Company, Miami Valley Innovation Center, Cincinnati, OH, 45253, US. bConsultant in Investigative Toxicology, P.O. Box 29225, St. Andrews, Fife, KY16 9WS, UK. cThe Procter & Gamble Company, Sharon Woods Technical Center, Cincinnati, OH, 45241, US.
Toxicology Letters, 188, 119–129, 2009.
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515. |
NEW! |
FOLLOW-UP VALIDATION OF THE EPIDERM SKIN IRRITATION TEST (SIT): RESULTS OF A MULTI-CENTRE STUDY OF TWENTY REFERENCE TEST SUBSTANCES.
Liebsch1, M., Gamer2, A.O., Curren3, R.D., Frank4, J., Genschow1, E., Tharmann1, J., Remmele2, M., Bauer2, B., Raabe3, H., Barnes3, N., Hilberer3, A., Wilt3, N., Lornejad-Schäfer4, M.R., Schäfer4, C., Hayden5, P. and Kandárová5, H.
1Unit 37 at the BfR (ZEBET) - Federal Institute for Risk Assessment, Berlin, Germany, 2BASF SE - Experimentelle Toxikologie und Oekologie, Ludwigshafen, Germany. 3Institute for In Vitro Sciences, Inc., Gaithersburg, Maryland, USA, 4Centre for Alternative and Complementary Methods to Animal Testing (zet–LSL), Linz, Austria, 5MatTek Corporation, Ashland, Massachusetts, USA.
Presented at SOT Expo 2009, Baltimore, MD.
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512. |
NEW! |
FURTHER DEVELOPMENT OF THE EPIDERM 3D RECONSTRUCTED HUMAN SKIN MICRONUCLEUS (RSMN) ASSAY.
Muna, G.C., Aardemab, M.J., Hub, T., Barnettc, B., Kaluzhnyd, Y., Klausnerd, M., Karetskyd, V., Dahla, E.L., Currena, R.D.
aInstitute for In Vitro Sciences Inc., 30 W. Watkins Mill Road, Suite 100, Gaithersburg, MD 20878, USA. bThe Procter & Gamble Co., P.O. Box 538707, Cincinnati, OH 45253, USA. cAdvanced Testing Laboratory, 6954 Cornell Road, Suite 200, Cincinnati, OH 45242, USA. dMatTek Corp., 200 Homer Ave., Ashland, MA 01721, USA.
Mutat. Res., 673, 92-99, (2009).
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511. |
NEW! |
INTRALABORATORY AND INTERLABORATORY EVALUATION OF THE EPIDERM 3D HUMAN RECONSTRUCTED SKIN MICRONUCLEUS (RSMN) ASSAY.
Hua, T., Kaluzhnyb, Y., Munc, G.C., Barnettd, B., Karetskyb, V., Wiltc, N., Klausnerb, M., Currenc, R.D., Aardemaa, M.J.
aThe Procter & Gamble Co., P.O. Box 538707, Cincinnati, OH 45253, United States bMatTek Corporation, 200 Homer Avenue, Ashland, MA 01721, United States, cInstitute for In Vitro Sciences, Inc., 30 West Watkins Mill Road, Suite 100, Gaithersburg, MD 20878, United States, dAdvanced Testing Laboratory, 6954 Cornell Road, Suite 200, Cincinnati, OH 45242, United States.
Mutat. Res., 673, 100-108 (2009).
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505. |
NEW! |
EVALUATION OF PRO-INFLAMMATORY BIOMARKERS OF IRRITATION IN HUMAN SKIN MODEL USING MULTIPLEXED IMMUNOASSAY.
Izbicka1, E., Yee2, B., Zhang2, A., Streeper1, R.T.
1BTNS LLC, San Antonio, TX, USA and 2Panomics Inc., Fremont, CA, USA.
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501. |
NEW! |
INHIBITING THE EFFECTS OF OXIDATIVE STRESS VIA TOPICALLY APPLIED ANTIOXIDANT FORMULATIONS.
Betteridge1, J.W., Blenkiron1, P., Flood2, J., Johnson2, M., Sun2, Y., Zeller3, A., Zhu2, C.
1P&G Beauty, Egham, UK; 2Cincinnati, Ohio, USA; 3Marly, Switzerland.
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499. |
NEW! |
LINKER-BASED LECITHIN MICROEMULSIONS FOR TRANSDERMAL DELIVERY OF LIDOCAINE.
Yuan, J.S., Ansari, M., Samaan, M., Acosta, E.J.
University of Toronto, Department of Chemical Engineering and Applied Chemistry, 200 College St., Toronto, ON, Canada M5S 3E5.
International J. of Pharmaceuticals, 349, 130-143, (2008).
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496. |
NEW! |
THE USE OF RECONSTRUCTED HUMAN EPIDERMIS FOR SKIN ABSORPTION TESTING: RESULTS OF THE VALIDATION STUDY.
Schäfer-Korting1, M., Bock2, U., Diembeck3, W., Düsing3, H-J., Gamer4, A., Haltner-Ukomadu2, E., Hoffmann5, C., Kaca2, M., Kamp4, H., Kersen6, S., Kietzmann7, M., Korting8, H.C., Krächter9, H-U., Lehr10, C-M., Liebsch11, M., Mehling9, A., Müller-Goymann5, C., Netzlaff10, F., Niedorf7, F., Rübbelke8, M.K., Schäfer10, U., Schmidt11, E., Schreiber1, S., Spielmann11, H., Vuia1, A., and Weimer6, M.
1Freie Universität Berlin, Institut für Pharmazie, Berlin, Germany; 2Across Barriers GmbH, Saarbrücken, Germany; 3Beiersdorf AG, Hamburg, Germany; 4BASF Aktiengesellschaft, Experimental Toxicology & Ecology, Ludwigshafen, Germany; 5Technische Universität Carolo-Wilhelmina zu Braunschweig, Institut für Pharmazeutische Technologie, Braunschweig, Germany; 6Fraunhofer Institut für Grenzflächen- & Bioverfahrenstechnik, Stuttgart, Germany; 7Stiftung Tierärztliche Hochschule Hannover, Institut für Pharmakologie, Toxikologie & Pharmazie, Hannover, Germany; 8Ludwig-Maximilians-Universität München, Klinik & Poliklinik für Dermatologie & Allergologie, Munich, Germany; 9Cognis Deutschland GmbH & Co. KG, Düsseldorf, Germany; 10Universität des Saarlandes, Biopharmazie & Pharmazeutische Technologie, Saarbrücken, Germany; 11Zentralstelle zur Erfassung & Bewertung von Ersatz- & Ergänzungsmethoden zum Tierversuch (ZEBET) am Bundesinstitut für Risikobewertung, Berlin, Germany.
ATLA, 36, 161-187 (2008).
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495. |
NEW! |
RECONSTRUCTED EPIDERMIS AND FULL-THICKNESS SKIN FOR ABSORPTION TESTING: INFLUENCE OF THE VEHICLES USED ON STEROID PERMEATION.
Schäfer-Korting1, M., Mahmoud1, A., Borgia1, S.L., Brüggener1, B., Kleuser1, B., Schreiber1, S., and Mehnert2, W.
1Freie Universität Berlin, Institut für Pharmazie (Pharmakologie & Toxikologie), Berlin, Germany; 2Freie Universität Berlin, Institut für Pharmazie (Pharmazeutische Technologie), Berlin, Germany.
ATLA, 36, 441-452, (2008).
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493. |
NEW! |
MOLECULAR RESPONSE OF NASAL MUCOSA TO THERAPEUTIC EXPOSURE TO BROAD-BAND ULTRAVIOLET RADIATION.
Mitchell1, D., Paniker1, L., Sanchez1, G., Bella2, Z., Garaczi3, E., Szell4, M., Hamid5, Q., Kemeny3,4, L., and Koreck3,6, A.
1Department of Carcinogenesis, University of Texas MD Anderson Cancer Center, Smithville, Texas, USA. 2Department of Otolaryngology, Head and Neck Surgery, University of Szeged, Hungary. 3Department of Dermatology and Allergology, University of Szeged, Hungary. 4Dermatological Research Group of the Hungarian Academy of Sciences, Szeged, Hungary. 5Meakins-Christie Laboratories, McGill University , Montreal, Quebec, Canada. 6Department of Immunology, Victor Babes University, Timisoara, Romania.
J. of Cellular and Molecular Medicine, In press, 2008.
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491. |
NEW! |
DEVELOPMENT OF AN IN VITRO CORROSION/IRRITATION PREDICTION ASSAY USING THE EPIDERM™ SKIN MODEL.
Kidd1,2, D.A., Johnson1, M., Clements1, J.
1Department of Genetic and Molecular Toxicology, Covance Laboratories Ltd., Otley Road, Harrogate, North Yorkshire HG3 1PY, UK. 2Department of Biology, University of York, Heslington, York, North Yorkshire YO1 7EP, UK.
Toxicology In Vitro, 21, 1292-1297 (2007).
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489. |
NEW! |
ENSURING QUALITY OF IN VITRO ALTERNATIVE TEST METHODS: ISSUES AND ANSWERS.
Gupta1, K., Rispin2, A., Stitzel3, K., Coecke4, S., Harbell5, J.
1US Consumer Product Safety Commission, Bethesda, MD, USA. 2US Environmental Protection Agency, Office of Pesticide Programs (7506C), Washington, DC, USA. 3Consultant, West Chester, OH, USA. 4European Center for the Validation of Alternative Methods, Institute for Health and Consumer Protection, European Commission Joint Research Center, Ispra, Italy. 5Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA.
Reg. Toxicol. and Pharma, 43, 219-224, (2005).
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487. |
NEW! |
IN VITRO SKIN ABSORPTION AND DRUG RELEASE – A COMPARISON OF SIX COMMERCIAL PREDNICARBATE PREPARATIONS FOR TOPICAL USE.
Lombardi Borgia1, S., Schlupp1,2, P., Mehnert3, W., Schafer-Korting1, M.
1Institut fur Pharmazie (Pharmakologie und Toxikologie), Freie Universitat Berlin, Berlin, Germany, 2Institut fur Biochemie und Molekularbiologie, Charite–Universitatsmedizin Berlin, Berlin, Germany, 3Institut fur Pharmazie (Pharmazeutische Technologie), Freie Universitat Berlin, Berlin, Germany.
European J. of Pharma. and Biopharma, 68, 380-389, (2008).
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479. |
NEW! |
PARTICLE SIZE AND BILAYER RIGIDITY EFFECTS ON SKIN DIFFUSION OF NANOSOMES.
Papazoglou1,2, E.S., Babu1, S., Fan1, C., Sunkari1, C., and Uitto2, J.
1Biomedical Engineering, Drexel University, Philadelphia, PA and 2Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, PA.
Abstract International Invest. Dermatol., Abstract 324, May (2008).
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478. |
NEW! |
INITIAL IN VITRO SCREENING APPROACH TO INVESTIGATE THE POTENTIAL HEALTH AND ENVIRONMENTAL HAZARDS OF ENVIROX™ – A NANOPARTICULATE CERIUM OXIDE DIESEL FUEL ADDITIVE.
Park1, B., Martin2, P., Harris1, C., Guest3, R., Whittingham3, A., Jenkinson3, P., and Handley3, J.
1Oxonica, 7 Begbroke Science Park, Sandy Lane, Yarnton, Oxfordshire, UK, 2Product Assessment & Regulatory Compliance, Sydney Road, Cradley Heath, West Midlands, UK and 3SafePharm Laboratories Ltd, London Road, Shardlow, Derby, UK.
Particle and Fibre Toxicology, 4, 12, December (2007).
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466. |
NEW! |
AN IN VITRO MODEL SYSTEM TO STUDY THE DAMAGING EFFECTS OF PROLONGED MECHANICAL LOADING OF THE EPIDERMIS.
Bronneberg, D., Bouten, C.V.C., Oomens, C.W.J., Van Kemenade, P.M. and Baaijens, F.P.T.
Department of Biomedical Engineering, Eindhoven University of Technology, P.O. Box 513, 5600 MB, Eindhoven, The Netherlands.
Annals of Biomed. Engineering, 34, 3, 506-514, (2006).
|
465. |
NEW! |
SUNSCREEN ENHANCEMENT OF UV-INDUCED REACTIVE OXYGEN SPECIES IN THE SKIN.
Hanson1, K.M., Gratton2, E., Bardeen1, C.J.
1Department of Chemistry, University of California at Riverside, Riverside, CA 92506, USA. 2Laboratory for Fluorescence Dynamics, Department of Bioengineering, University of California at Irvine, Irvine, CA 92697, USA.
Free Radical Bio. & Medicine, 41, 1205-1212, (2006).
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464. |
NEW! |
COMPARISON OF HUMAN PATCH TEST AND 3D HUMAN SKIN MODEL RESULTS WITH CLASSIFICATION OF CHEMICALS BASED ON RABBIT DRAIZE TEST.
Bendova1, H., Basketter2, D., Kandarova3, H., Marriott4, M., Kejjlova1,K., Jirova1, D., Spiller3, E., Maly1, M., and Liebsch5, M.
1National Institute of Public Health, CZ – Prague, 2St. John’s Institute of Dermatology, St. Thomas’ Hospital, London, UK, 3MatTek Corporation, Ashland, MA, USA, 4Safety and Environmental Assurance Center, Unilever Colworth Laboratory, UK – Bedford, 5ZEBET, Federal Institute for Risk Assessment, D – Berlin.
11th Annual Meeting of MEGAT, Univ. of Linz, Austria, September (2007).
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463. |
NEW! |
CHARACTERIZATION OF THE EFFECT OF URINE ON MECHANICALLY INDUCED SKIN DAMAGE.
Sonsma1, J.,
Grin1, P.C., Jorritsma1, P.A., Bronneberg2, D., Bouten2, C.V.C., Oomens2, C.W.J., and Baaijens2, F.P.T.
1VHall Instituut Leeuwarden, Unit Life Sciences, Biotechnology. 2Eindhoven University of Technology, Department of Biomedical Engineering, Section Soft Tissue Biomechanics and Engineering.
BMTE, 06.28, (2006).
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462. |
NEW! |
CYTOKINE AND CHEMOKINE RELEASE UPON PROLONGED MECHANICAL LOADING OF THE EPIDERMIS.
Bronneberg1, D., Spiekstra2, S.W., Cornelissen1, L.H., Oomens1, C.W.J., Gibbs2, S., Baaijens1, F.P.T. and Bouten1, C.V.C.
1Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands. 2Department of Dermatology, VU University Medical Center, Amsterdam, The Netherlands.
Dermatology, 16, 567-573, (2007).
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461. |
NEW! |
IN VITRO SKIN CORROSION TEST: LONG TERM REPRODUCIBILITY AND RELIABILITY FOR A REGULATORY ACCEPTED METHOD.
Chua1, G., Kandarova1, H., Raabe2, H., Klausner1, M., Kubilus1, J., Hayden1, P., Ayehunie1, S., Kaluzhny1, Y., Curren2, R., Sheasgreen1, J.
1MatTek Corporation, Ashland, MA; 2Institute for In Vitro Sciences, Inc. Gaithersburg, MD.
Presented at 6th World Congress on Alternatives and Animal Use, Tokyo, August (2007).
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459. |
|
IN VITRO SKIN IRRITATION TEST: INCREASING THE SENSITIVITY OF THE EPIDERM SKIN IRRITATION PROTOCOL EVALUATED IN THE ECVAM SKIN IRRITATION VALIDATION STUDY.
Kandárová1, H., Torishima2, H., Hayden1, P., Spiller1, E., Klausner1, M., Kubilus1, J., and Sheasgreen1, J.
1MatTek Corporation, Ashland, MA; 2Kurabo Industries, Ltd., Osaka, Japan.
Presented at 6th World Congress on Alternatives and Animal Use, Tokyo, August (2007). Presented at 44th Congress of the European Societies of Toxicology, Amsterdam, The Netherlands, 2007.
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458. |
|
GENOTOXICITY TESTING USING THE MICRONUCLEUS ASSAY IN THE EPIDERM™ HUMAN 3D SKIN MODEL.
Kaluzhny1, Y., Curren2, R., Aardema3, M., Hu3, T., Klausner1, M., Karetsky1, V., Hayden1, P., Kandarova1, H., Sheasgreen1, J.
1MatTek Corporation, Ashland, MA, USA; 2Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA; 3The Procter & Gamble Co., Cincinnati, OH, USA.
Presented at the 6th World Congress on Alternatives and Animal Use in the Life Sciences, Tokyo, Japan August 21-25, (2007).
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452. |
|
INHIBITION OF TUMOUR NECROSIS FACTOR-Á SECRETION FROM EPIDERM TISSUES BY A NOVEL SMALL MOLECULE, UTL-5D.
Shaw1, J., Liu1, C., Martin1, R., Chen2, B., Holtz3, R., Huanq4, W.H, Lee4, A.R.
1Unitech Pharmaceuticals, Inc., 4370 Varsity Drive, Ann Arbor, MI 48108, USA, 2Department of Internal Medicine, Wayne State University, Detroit, MI, USA, 3BioInnovation Laboratories, Inc., Lakewood, CO, USA, 4School of Pharmacy, National Defense Medical Center, Taipei, Taiwan.
Br. J. of Dermatology, 157, 575-579, (2007).
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444. |
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AN IN VITRO SYSTEM FOR PREDICTING SKIN IRRITATION OF LIQUID ANTIPERSPIRANTS.
McPhail, S., Lanzalaco, A.C., Kolodzik, J., Osborne, R.
Procter & Gamble Company, Mason, OH 45040.
68th Annual Meeting of the Society for Investigative Dermatology, Los Angeles, CA, (2007).
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443. |
|
USE OF THE COMET ASSAY TO DETECT GENOTOXIC EFFECTS IN RECONSTITUTED HUMAN SKIN.
Zeller, A., Richoz, L., Corbino, L. and Pfuhler, S.
Experimental Product Safety, The Procter & Gamble Co., Wella-Cosmital SA, Marly, Switzerland.
Society of Toxicology 46th Annual Meeting, Charlotte, NC, (2007). Abstract #1171. The Toxicologist, 96, 1, 243 (2007).
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442. |
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REGULATORY REQUIREMENTS FOR IN VITRO SYSTEMS TO MEET PERFORMANCE STANDARDS OVER TIME AS WELL AS DURING VALIDATION.
Klausner, M., Kubilus, J., Ayehunie, S., Hayden, P., Chua, G., Sheasgreen, J.
MatTek Corporation, Ashland, MA 01721.
Society of Toxicology 46th Annual Meeting, Charlotte, NC, Abstract 1524, (2007). The Toxicologist, 96, 1, 315 (2007).
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441. |
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COMPARISON OF IN VITRO PHOTOTOXICITY TEST METHODS: 3T3 NRU PT VS. ENHANCED PHOTOTOXICITY SCREENING ASSAY IN RECONSTITUTED SKIN (EPARS).
Pratt, L., Kirk, C., Reeder, M., DeGeorge, G.
MB Research Laboratories, Spinnerstown, PA.
Society of Toxicology 46th Annual Meeting, Charlotte, NC, (2007)., Poster 441. The Toxicologist, 96, 1, 315 (2007).
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437. |
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INJURY ENHANCES TLR2 FUNCTION AND ANTIMICROBIAL PEPTIDE EXPRESSION THROUGH A VITAMIN D–DEPENDENT MECHANISM.
Schauber1, J., Dorschner1, R.A., Coda1, A.B., Büchau1, A.S., Liu2, P.T., Kiken1, D., Helfrich3, J.R., Kang3, S., Elalieh4, H.Z., Steinmeyer5, A., Zügel6, U., Bikle4, D.D., Modlin2, R.L. and Gallo1, R.L.
1Division of Dermatology, University of California, San Diego, and VA San Diego Healthcare System, San Diego, California, USA; 2Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA; 3Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA; 4Department of Medicine, Endocrine Unit, Veterans Affairs Medical Center, University of California, San Francisco, San Francisco, California, USA; 5Medicinal Chemistry and 6Corporate Research Business Area Inflammation, Schering AG, Berlin, Germany.
J. Clinical Invest., 117, (3), 803-811, (2007).
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435. |
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COMPARISON OF CORROSITEX AND EPIDERM IN VITRO SKIN CORROSION SCREENING ASSAYS TO IN VIVO CORROSIVITY RESULTS.
Wilson, D.M., McMullin, T.T. Kan, H.L., Golden, R.M. Stott, W.T.
Dow Chemical, Midland, MI, USA.
Society of Toxicology 46th Annual Meeting, Charlotte, NC, (2007). The Toxicologist, 96, 1, 144 (2007).
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434. |
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IN VITRO AND IN VIVO COMPARISON OF DERMAL IRRITANCY OF JET FUEL EXPOSURE USING EPIDERM (EPI-200) CULTURED HUMAN SKIN AND HAIRLESS RATS.
Chatterjee1, A., Babu2, R.J., Klausner3, M., Singh1, M.
1College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL 32307, United States; 2Department of Pharmacal Sciences, Harrison School of Pharmacy, Auburn University, AL 36849, United States; 3MatTek Corporation, 200 Homer Avenue, Ashland, MA 01721, United States.
Toxicology Letters, 167, 85-94, (2006).
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433. |
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INJURY-INDUCED INNATE IMMUNE RESPONSE IN HUMAN SKIN MEDIATED BY TRANSACTIVATION OF THE EPIDERMAL GROWTH FACTOR RECEPTOR.
Sorensen1, O.E., Thapa2, D.R., Roupe1, K.M., Valore2, E.V., Sjobring1, U., Roberts2, A.A., Schmidtchen3, A., and Ganz2, T.
1Section of Clinical and Experimental Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden. 2Host Defense Research Laboratory, Department of Medicine and Pathology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA. 3Department of Dermatology and Venereology, Lund University, Lund, Sweden.
J. Clinical Invest., 116, (7), 1878-1885, (2006).
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432. |
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THE EFFECTS OF IL-20 SUBFAMILY CYTOKINES ON RECONSTITUTED HUMAN EPIDERMIS SUGGEST POTENTIAL ROLES IN CUTANEOUS INNATE DEFENSE AND PATHOGENIC ADAPTIVE IMMUNITY IN PSORIASIS.
1Sa, S.M., Valdez, P.A., Wu, J., Jung, K., Zhong, F., Hall, L., Kasman, I., Winer, J., Modrusan, Z., Danilenko, D.M., Ouyang, W.
1Genentech, Department of Pathology, South San Francisco, CA.
Immunology, 2229-2240 (2007).
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427. |
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FURTHER DEVELOPMENT OF A MICRONUCLEUS ASSAY USING THE HUMAN 3-D SKIN MODEL, EPIDERM™.
Curren1, R.D., Aardema², M.J., Hayden³, P.J., Mun1, G., Hu², T.
1Institute for In Vitro Sciences, Gaithersburg, MD, ²Procter & Gamble, Cincinnati, OH, ³MatTek Corporation, Ashland, MA.
Presented at the 14th International Workshop on In Vitro Toxicology, Ostend, Belgium, October 2-5, (2006).
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423. |
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THE COLIPA STRATEGY FOR THE DEVELOPMENT OF IN VITRO ALTERNATIVES: GENOTOXICITY.
Pfuhler1, S., Meunier2, J-R., Aardema3, M., Banduhn4, N., Fautz5, R., Manou6, I., Wolfreys7, A.
1Wella AG, Darmstadt, Germany, 2L’Oreal, Paris, France, 3Procter & Gamble, Cincinnati, OH, 4Henkel, Düsseldorf, Germany, 5Kao Professional Salon Services, Darmstadt, Germany, 6COLIPA, Brussels, Belgium, 7Unilever, Bedford, England.
Presented at the 5th World Congress, Berlin, Germany, August 21-25, (2005).
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419. |
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GENE EXPRESSION PROFILING OF SKIN CARCINOGENSIS IN MICE.
Ridd1, K., Davies1, R., Judah1, D., Riley1, J., Zhang1, S.D, Wolfreys2, A., Greaves1, P., Gant1, T., Smith1, A.
1MRC Toxicology Unit, University of Leicester, Leicester, UK, 2Safety Environmental Assurance Centre, Unilever, Colworth, Bedford, UK.
Presented at the 6th Long-Range Research Initiative (LRI) Member Workshop, Brussels, Belgium, November 17-18, (2004).
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417. |
|
DESIGN PRINCIPLES OF CHEMICAL PENETRATION ENHANCERS FOR TRANSDERMAL DRUG DELIVERY.
Karande, P., Jain, A., Ergun, K., Kispersky, V., Mitragotri, S.
Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, CA 93106.
PNAS, 102, 13, 4688-4693 (2005)
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416. |
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TGF-á REGULATES TLR EXPRESSION AND FUNCTION ON EPIDERMAL KERATINOCYTES.
Miller1, L.S., Sorensen1, O.E., Liu1, P.T., Jalian1, H.R., Eshtiaghpour1, D., Behmanesh1, B.E., Chung1, W., Starner2, T.D., Kim1, J., Sieling1, P.A., Ganz1, T., Modlin1, R.L.
1David Geffen School of Medicine, University of California, Los Angeles, California, 2Department of Pediatrics, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
The Journal of Immunology, 174, 6137-6143, (2005).
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412. |
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IN VITRO SCREEN FOR PHOTOTOXICITY OPTIMIZED DRUG DEVELOPMENT USING A HIGHLY DIFFERENTIATED SKIN MODEL.
Klausner, M., Neal, P., Kubilus, J.
MatTek Corporation, Ashland, MA.
Presented at the AAPS 2006 Biotechnology Conference, Boston, MA., June (2006).
|
405. |
|
XENOBIOTIC METABOLIZING CAPABILITIES OF THE EPIDERM IN VITRO HUMAN SKIN EQUIVALENT.
Bolmarcich©ö, J., Hayden©ö, P. J., Stolper©ö, G., Hu©ø, T., Aardema©ø, M., Curren©÷, R., Klausner©ö, M.
©öMatTek Corp., Ashland, MA, USA. ©÷Institute for In Vitro Sciences, Gaithersburg, MD, USA. ©øProcter and Gamble Co., Cincinnati, OH, USA.
Presented at the Society of Investigative Dermatology Annual Meeting, Philadelphia, PA, May 3-6 (2006).
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403. |
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EFFECTS IN UNIRRADIATED HUMAN TISSUE INDUCED BY RADIATION DAMAGE UP TO 1 MM AWAY.
Belyakov1,2, O.V., Mitchell1, S.A., Parikh3, D., Randers-Pehrson1, G., Marino1, S.A., Amundson1, S.A., Geard1, C.R. and Brenner1, D.J.
1Center for Radiological Research, Columbia University, New York, NY 10032; 2Radiation Biology Laboratory, Research and Environmental Surveillance, Radiation and Nuclear Safety Authority, P.O. Box 14, FIN-00881, Helsinki, Finland; and 3Stuyvesant High School, New York, NY 10282.
Proceedings of the Natl. Acad.of Sci. of the U.S.A, 102, 40, 14203-14208, October (2005).
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401. |
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EVALUATION OF EPIDERM™ AS A MODEL TO STUDY IRRITATION AFTER EXPOSURE TO VARIOUS ALIPHATIC HYDROCARBONS FOUND IN JET FUELS.
Singh1, M., Babu2, R.J., Chatterjee1, A., Fulzele1, S.V., Klausner3, M., Kubilus3, J.
1College of Pharmacy, Florida A&M University, Tallahassee FL; 2Harrison School of Pharmacy, Auburn University AL; 3MatTek Corporation, 200 Homer Avenue, Ashland MA.
Presented at the 45th Society of Toxicology Meeting, San Diego, CA, March 5-9, (2006). The Toxicologist, 90, 1, 325 (2006).
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397. |
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PROTEOMIC ANALYSIS OF THE RESPONSE OF EPIDERM™ CULTURES TO SODIUM LAURYL SULPHATE.
Fletcher, S.T., Basketter, D.A.
Safety and Environmental Assurance Centre (SEAC), Unilever Colworth, Sharnbrook, Bedfordshire, UK.
Toxicology In Vitro, 20, (6), 975-985, (2006).
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392. |
|
USE OF HUMAN SKIN EQUIVALENT CULTURES FOR COSMETIC BENEFIT SCREENING.
McPhail1, S., Messersmith1, E., Thomas1, R., Mullins1, L., Osborne1, R., Grove2, G.
1Procter and Gamble, Miami Valley Innovation Center, Beauty Technology Division, 11810 East Miami River Road Cincinnati, OH 45252. 2CyberDERM, 700 Parkway, Broomall, PA 19008.
Presented at the American Academy of Dermatology, New Orleans, LA, February 19, (2005).
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387. |
|
PROTECTING THE SKIN AGAINST OZONE.
Gruber1, J.V., Tay1, A., Holtz2, R.
1Arch Personal Care Products, South Plainfield, NJ; 2BioInnovation Laboratories, Inc., McKinney, TX.
Journal of Cosmetic Sciences, 56, (5), 348-349, (2005).
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385. |
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USE OF EPIDERM FULL THICKNESS TISSUE FOR ANTI-AGING STUDIES.
Gruber, V., et al.
Arch Personal Care Products L.P., South Plainfield, NJ and BioInnovation Laboratories, Inc., McKinney, TX.
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381. |
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VALIDATION OF HUMAN SKIN MODELS FOR SKIN CORROSIVITY TESTS IN JAPAN.
Ohno1, Y., Ando2, T., Inagaki3, K., Ohhira4, M., Kosaka5, T., Kojima6, H., Nakamura7, Y., Torishima8, H., Morikawa9, N., Omori10, T., Kanno2, J., Kuboki4, M., Genno8, M., Nokata3, M., Harada5, T.,Morimoto7, T., Yoshimura11, I.
1Div. Pharmacology, NIHS, 2Div. Toxicol. NIHS, 3Research Division, Nihon Nohyaku Co., Ltd., 4Toxicological Research Department, ODAWARA Research Center, Nippon Soda Co., Ltd., 5Toxicol. Div. The Inst. Environmental Toxicol., 6Res. Lab., Nippon Menard Cosmetic Co., Ltd., 7Environmental Health Science Lab., Sumitomo Chemical Co., Ltd., 8Bio-Medical Department, Kurabo Industries Ltd. 9Div. R&D, Gunze Ltd., 10Fac. Med. Kyoto Univ., 11Fac. Eng. Tokyo Univ. Science.
Presented at 5th World Congress, Berlin, Germany, August, (2005).
|
380. |
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CHARACTERIZATION OF THE EPIDERM™ HUMAN 3-D SKIN MODEL FOR GENOTOXICITY TESTING.
Aardema1, M., Curren2, R., Hayden3, P., Mun2, G., Gibson1, D., Hu1, T.
1The Procter & Gamble Co., Cincinnati, OH, USA; 2Institute for In Vitro Sciences, Gaithersburg, MD, USA; 3MatTek Corp., Ashland MA, USA.
Presented at 5th World Congress, Berlin, Germany, August, (2005).
|
378. |
|
RECONSTRUCTED HUMAN EPIDERMIS FOR SKIN ABSORPTION TESTING: RESULTS OF THE GERMAN PREVALIDATION STUDY.
Schafer-Korting1, M., Bock2, U., Gamer3, A., Haberland1, A., Haltner-Ukaomadu2, E., Kaca2, M., Kamp3, H., Kietzmann4, M., Korting5, H.C., Krachter6, H-U., Lehr7, C.M., Liebsch8, M., Mehling6, A., Netzlaff7, F., Niedorf4, F., Rubbelke5, M.K., Schafer7, U., Schmidt8, E., Schreiber1, S., Schroder9, K-R., Spielmann8, H., Vuia1, A.
1Freie Universität Berlin, Institut für Pharmazie, Berlin, Germany, 2Across Barriers GmbH, Saarbrücken, Germany, 3BASF Aktiengesellschaft, Experimental Toxicology and Ecology, Ludwigshafen, Germany, 4Stiftung Tierärztliche Hochschule Hannover, Institut für Pharmakologie, Hannover, Germany, 5Ludwig-Maximilians-Universität München, Klinik und Poliklinik für Dermatologie und Allergologie, München, Germany, 6Cognis Deutschland GmbH & Co. KG, Düsseldorf, Germany, 7Universität des Saarlandes, Biopharmazie u. Pharmazeutische Technologie, Saarbrücken, Germany, 8ZEBET, Berlin, Germany, 9Henkel KGaA, Düsseldorf, Germany.
ATLA, 34, 283-294 (2006).
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377. |
|
PROGRAM TO REDUCE ANIMAL TESTING FOR EPA REGISTRATIONS OF ANTIMICROBIAL PRODUCTS.
Sauers1, L., Acuff1, K., Marsman1, D., Vedula2, U., Cuellar2, N., Curren3, R., Harbell3, J., Quinn4, P.
1The Proctor & Gamble Co., Cincinnati, Ohio, USA; 2S.C. Johnson, Racine, Wisconsin, USA; 3Institute for In Vitro Sciences, Gaithersburg, Maryland, USA; 4The Accord Group, Washington, DC, USA.
|
372. |
|
ECVAM FEASIBILITY STUDY: CAN THE PRE-VALIDATED IN VITRO SKIN MODEL PHOTOTOXICITY ASSAY BE UPGRADED TO QUANTIFY PHOTOTOXIC POTENCY OF TOPICAL PHOTOTOXINS?
Kandárová1, H., Kejlová2, K., Jírová2, D., Bendová2, H., Tharmann1, J., Traue1, D., Spielmann1, H., Liebsch1, M.
1ZEBET at the BfR (Federal Institute for Risk Assessment), Berlin, Germany; 2National Institute of Public Health (SZU), Prague, Czech Republic.
Presented at 5th World Congress, Berlin, Germany, August 21-25, (2005).
|
371. |
|
IN VITRO SKIN EQUIVALENT MODELS FOR TOXICITY TESTING.
Hayden, P.J., Ayehunie, S., Jackson, G.R., Kupfer-Lamore, S., Last, T.J., Klausner, M., Kubilus, J.
MatTek Corporation, Ashland, MA, U.S.A.
Published in Alternative Toxicological Methods. Editors H. Salem, S.A. Katz. CRC Press LLC, Boca Raton, FL, USA, 229-247 (2003).
|
369. |
|
BIOCONVERSION OF NALTREXONE AND ITS 3-O-ALKYL-ESTER PRODRUGS IN A HUMAN SKIN EQUIVALENT.
Hammell1, D.C., Stolarczyk1, E.I., Klausner2, M., Hamad1, M.O., Crooks1, P.A., Stinchcomb1, A.L.
1Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536-0082; 2MatTek Corporation, Ashland, Massachusetts 01721.
J Pharm Sci, 94, 828–836, (2005).
|
367. |
|
DIFFERENTIAL REGULATION OF â-DEFENSIN EXPRESSION IN HUMAN SKIN BY MICROBIAL STIMULI.
Sørensen2, O.E., Thapa, D.R., Rosenthal, A., Liu, L., Roberts, A.A., Ganz, T.
Host Defense Laboratory, Department of Pathology and Laboratory Medicine, David
Geffen School of Medicine, University of California, Los Angeles, CA, 2Department of Clinical Sciences, Biomedical Center B14, Lund University, Lund, Sweden.
J Immunology, 174, 4870–4879, (2005).
|
366. |
|
ANALYSIS OF GLOBAL GENE EXPRESSION PROFILE CHANGES DURING THE DIFFERENTIATION OF THE EPIDERM™ IN VITRO HUMAN SKIN EQUIVALENT.
Street1, T.L., Hayden2, P.J., Hao1, L., Taylor3, J., Copley1, R., Hein3, J., Moffatt1, M., Cookson1, W.O.C.M.
1Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, England; 2MatTek Corporation, Ashland, MA, United States and 3Oxford Centre for Gene Function, University of Oxford, Oxford, England.
Presented at Society of Investigative Dermatology, St.Louis, MO, May 4-7, (2005).
|
361. |
|
CYTOKINE RELEASE OF A KERATINOCYTE MODEL AFTER INCUBATION WITH TWO DIFFERENT VISCUM ALBUM L EXTRACTS.
Gorter1,2,3,4, R.W., Joller5, P., Stoss1,6, M.
1Medical Section at the Goetheanum, School for Spiritual Science, Dornach, Switzerland; 2International Institute for Oncological and Immunological Research, Cologne, Germany; 3University of California, San Francisco, CA, USA; 4University Witten/Herdecke, Germany; 5PHOENIX-ANAWA, Wangen, Switzerland; 6School of Homeopathy, Technicon of the Witwatersrand, Johannesburg, South Africa.
American Journal of Therapeutics, 10, 40-47, (2003).
|
358. |
|
DEVELOPMENT OF A NOVEL MICRONUCLEUS ASSAY USING THE HUMAN 3-D SKIN MODEL, EPIDERM™.
Curren1, R., Mun1, G., Gibson2, D., Aardema2, M.
1Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA; 2The Procter & Gamble Co., Cincinnati, OH, USA.
Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. The Toxicologist, 84, (1), Abstract # 2209, 453, (2005).
|
357. |
|
EVALUATION OF A TISSUE ENGINEERED HUMAN SKIN EPIDERM 3-D CULTURE AS A MODEL TO STUDY IRRITATION AFTER JET FUEL EXPOSURE.
Chatterjee, A., Babu, R., Singh, M.
Florida A&M University, Tallahassee, FL, USA.
Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. The Toxicologist, 84, (1), Abstract # 2004, 410, (2005).
|
355. |
|
LONG TERM REPRODUCIBILITY OF EPIDERM, AN EPIDERMAL MODEL FOR DERMAL TESTING AND RESEARCH.
Klausner, M., Sheasgreen, J., Kubilus, J., Hayden, P.
MatTek Corporation, Ashland, MA.
Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. The Toxicologist, 84, (1), Abstract # 2191, 449, (2005).
|
354. |
|
HIGH-THROUGHPUT IN VITRO MODELS OF HUMAN EPIDERMIS AND OCULAR EPITHELIUM FOR PRECLINICAL SAFETY AND EFFICACY TESTING OF CONSUMER PRODUCTS AND PHARMACEUTICALS.
Jackson, G., Kubilus, J., Klausner, M., Sheasgreen, J., Hayden, P.
MatTek Corporation, Ashland, MA.
Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. The Toxicologist, 84, (1), Abstract # 2003, 409-410, (2005).
|
350. |
|
QUALITY ASSURANCE FOR IN VITRO ALTERNATIVE TEST METHODS: QUALITY CONTROL ISSUES IN TEST KIT PRODUCTION.
Rispin1, A., Harbell2, J.W., Klausner3, M., Jordan4, F.T., Coecke5, S., Gupta6, K., Stitzel7, K.
1US Environmental Protection Agency, Office of Pesticide Programs (7506C), Washington, DC, USA; 2Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA; 3MatTek Corporation, Ashland, MA, USA; 4Charles River Endosafe Corporation, Wilmington, MA, USA; 5European Centre for the Validation of Alternative Methods, Institute for Health and Consumer Protection, European Commission Joint Research Centre, Ispra, Italy; 6US Consumer Product Safety Commission, Bethesda, MD, USA; 7Consultant, West Chester, OH, USA.
ATLA, 32, (1), 725-729, (2004).
|
349. |
|
THE DEVELOPMENT OF AN IN VITRO SCREENING STRATEGY FOR TOPICALLY APPLIED PRODUCTS.
Horan1, I., Clotworthy2, M., Fokunang3, C., Tomkins1, P.
1School of Science (Bioserv Ltd. & CBBR), Athlone Institute of Technology, Athlone, Co. Westmeath, Ireland; 2MRC Laboratory of Molecular Biology, Cambridge, Cambridge, UK; 3School of Plant Sciences, University of Reading, Whiteknights, Reading RG6 6AS, UK.
J. Ethnopharmacol., 89, (1), 81-90, (2003).
|
346. |
|
DERMAL PENETRATION OF PESTICIDES AND POLYCHLORINATED BIPHENYLS FROM HOUSE DUST.
Ertl1, H., Müller2, M., Butte1, W.
1Carl-von-Ossietzky University of Oldenburg, Institute of Pure and Applied Chemistry, Oldenburg, Germany; 2Carl-von-Ossietzky University of Oldenburg, Institute of Biology and Environmental Sciences, Oldenburg, Germany.
|
343. |
|
DEVELOPMENT OF A MICRONUCLEUS ASSAY IN THE EPIDERM HUMAN 3D SKIN MODEL.
Curren1, R., Mun1, G., Gibson2, D., and Aardema2, M.
1Institute for In Vitro Sciences, Inc., Gaithersburg, MD; 2The Procter & Gamble Co., Cincinnati, OH.
Presented at the Environmental Mutagen Society Meeting, Pittsburgh, PA. October 2-6, (2004).
|
341. |
|
OPTIMISATION OF THE EPIDERM TEST PROTOCOL FOR THE UPCOMING ECVAM VALIDATION STUDY ON IN VITRO SKIN IRRITATION TESTS.
Kandárová, H., Liebsch, M., Genschow, E., Gerner, I., Traue, D., Slawik, B., Spielmann, H.
Centre for Documentation and Evaluation of Alternative Methods to Animal Experiments (ZEBET) at the BfR (Federal Institute for Risk Assessment), Berlin, Germany.
ALTEX, 21, 107-114, (2004).
|
338. |
|
ASSESSMENT OF SKIN ABSORPTION AND METABOLISM OF ARACHIDONIC ACID & GLYCERYL ARACHIDONATE USING IN VITRO DIFFUSION CELL TECHNIQUES.
Eppler1,2, A.R., Kraeling1, M.E.K., Wickett2, R.L., Bronaugh1, R.L.
1Office of Cosmetics and Colors/ Cosmetic Toxicology Branch, US Food & Drug Administration, Laurel, MD, 2College of Pharmacy, University of Cincinnati, Cincinnati, OH.
Poster Presented at the Society of Toxicology Annual Meeting, Baltimore, MD. March 21-25, (2004). The Toxicologist, 78, S1, 328 (2004).
|
337. |
|
ATTENUATION OF SURFACTANT-INDUCED INTERLEUKIN 1α EXPRESSION BY ZINC PYRITHIONE.
Warren1, R., Schwartz2, J., Sanders2, L., Juneja2, P.
1Winton Hill Technical Center, Procter & Gamble Co., Cincinnati, OH, 2Sharon Woods Technical Center, Procter & Gamble Co., Cincinnati, OH.
Exog Dermatol, 2, (1), 23-27, (2003).
|
336. |
|
ROLE OF TAURINE ACCUMULATION IN KERATINOCYTE HYDRATION.
Janeke*, G., Siefken, W., Carstensen, S., Springmann, G., Bleck**, O., Steinhart*, H., Höger**, P., Wittern, K.P., Wenck, H., Stäb, F., Sauermann, G., Schreiner, V., Doering, T.
R&D cosmed, Beiersdorf AG, Hamburg, Germany; *Department of Food Chemistry and **Department of Dermatology, University of Hamburg, Germany.
J. Invest. Dermatol., 121, (2), 354-361, (2003).
|
335. |
|
EFFECT OF A NEW BOTANICAL EXTRACT BASED ON THE RED ALGAE, PIKEA ROBUSTA, ON IN VIVO REDUCTION OF SURFACTANT-INDUCED SKIN IRRITATION.
Jindal, S., Johnson, C.H., Lods, L.M., Gruber, J.V., Qi, J.
Arch Personal Care Products, LP, 70 Tyler Place, South Plainfield, NJ 07080.
Application Note.
|
334. |
|
CONTRIBUTION OF UVB AND UVA TO UV- DEPENDENT STIMULATION OF CYCLOOXYGENASE-2 EXPRESSION IN ARTIFICIAL EPIDERMIS.
Mahns1,2, A., Wolber2, R., Stäb2, F., Klotz1, L.O., Sies1, H.
1Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, 40225 Düsseldorf, Germany, 2Beiersdorf AG, Cosmed Forschungszentrum, Unnastraße 48, 20245 Hamburg, Germany.
Photochemistry and Photobiology Science, (3), 257-262, (2004).
|
330. |
|
REINFORCEMENT OF INNATE HOST DEFENSE VIA INDUCTION OF ANTI-MICROBIAL PEPTIDES.
Goyarts, E., Sullivan, M., Muizzuddin,N., Schnittger, S., Mammone, T., Maes, D.
Skin Biology, Estee Lauder Companies, Melville, NY, USA
J. Invest. Dermatol., 122, (3), A79, Abstract #759, (2004).
|
327. |
|
DETECTING REACTIVE OXYGEN SPECIES IN SKIN USING TWO-PHOTON FLUORESCENCE IMAGING MICROSCOPY.
Hanson1, K., Hayden2, P., Kubilus2, J., Clegg1, R.
1Laboratory for Fluorescence Dynamics, Department of Physics, University of Illinois at Urbana-Champaign. 2MatTek Corp. 200 Homer Avenue, Ashland, MA.
J. Invest. Dermatol., 122, (3), A140, Abstract #839, (2004).
|
319. |
|
DISCOVERY OF TRANSDERMAL PENETRATION ENHANCERS BY HIGH-THROUGHPUT SCREENING.
Karande, P., Jain, A. and Mitragotri, S.
Department of Chemical Engineering, University of California, Santa Barbara, CA.
Nature Biotechnology, 22, (2), 192-197, (2004).
|
318. |
|
FLAVONOIDS DIFFERENTIALLY REGULATE IFN-GAMMA-INDUCED ICAM-1 EXPRESSION IN HUMAN KERATINOCYTES: MOLECULAR MECHANISMS OF ACTION.
Bito1,4, T., Roy2, S., Sen2, C.K., Shirakawa3, T., Gotoh3, A., Ueda4, M., Ichihashi4, M., Packer1,5, L.
1 Department of Molecular and Cell Biology, University of California, Berkeley, CA, 2Laboratory of Molecular Medicine, Davis Heart and Lung Research Institute, The Ohio State University Medical Center, Columbus, OH , 3Department of Urology, Kobe University Graduate School of Medicine, Japan, 4Department of Dermatology, Kobe University Graduate School of Medicine, Japan, 5Department of Molecular Pharmacology and Toxicology, School of Pharmacy, University of Southern California, Los Angeles, CA.
FEBS Letters, 520, 145-152, (2004).
|
317. |
|
FOLLOW-UP TO THE ECVAM PREVALIDATION STUDY ON IN VITRO TESTS FOR ACUTE SKIN IRRITATION.
Zuang1, V., Balls1, M., Bothan2, P.A., Coquette3, A., Corsini4, E., Curren5, R.D., Elliott6, G.R., Fentem7, J.H., Heylings2, J.R., Liebsch8, M., Medina9, J., Roguet10, R., van de Sandt11, J.J.M., Wiemann12, C., Worth1, A.P.
1ECVAM, Institute for Health & Consumer Protection, European Commission Joint Research Centre, Italy. 2Syngenta, Central Toxicology Laboratory, Cheshire, UK. 3SGS BioPharma, Wavre, Belgium. 4Laboratory of Toxicology, Milan, Italy. 5Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA. 6TNO-PML, Rijswijk, The Netherlands. 7SEAC Toxicology Unit, Unilever Research, Bedfordshire, UK. 8ZEBET, Berlin, Germany. 9Instituto de Salud Carlos III, Ciudad Unibersitaria, Madrid, Spain. 10L’Oreal Life Sciences Research, Cedex, France. 11TNO Nutrition & Food Research, Zeist, The Netherlands. 12BASF AG, Ludwigshafen, Germany.
ATLA, 30, 109-129 (2002).
|
316. |
|
AN ASSESSMENT OF THE PHOTOTOXIC HAZARD OF A PERSONAL PRODUCT INGREDIENT USING IN VITRO ASSAYS.
Jones, P.A., King, A.V., Earl, L.K., Lawrence, R.S.
Unilever Colworth, Bedfordshire, UK.
Toxicology in Vitro, 17, 471-480, (2003).
|
313. |
|
NALTREXONE AND NALTREXONE-3-O-VALERATE DIFFUSION AND BIOCONVERSION IN A HUMAN EPIDERMIS EQUIVALENT.
Stinchcomb1, A.L., Hammell1, D.C., Stolarczyk1, E.I., Klausner2, M., Hamad1, M., Crooks1, P.A.
1Division of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY, 2MatTek Corporation, Ashland, MA.
Poster presented at the American Association of Pharmaceutical Scientists (AAPS), Salt Lake City, UT, October 26-30, (2003).
|
309. |
|
WOUND HEALING AND EXPRESSION OF ANTIMICROBIAL PEPTIDES/ POLYPEPTIDES IN HUMAN KERATINOCYTES, A CONSEQUENCE OF COMMON GROWTH FACTORS.
Sorenson1,2, O.E., Cowland1, J.B., Theilgaard-Monch1, K., Liu2, L., Ganz2, T. and Borregaard1, N.
1Granulocyte Research Laboratory, Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark. 2Host Defense Research Laboratory, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095.
The Journal of Immunology, 170, 5583-5589, (2003).
|
308. |
|
BY IL-1 SIGNALING, MONOCYTE-DERIVED CELLS DRAMATICALLY ENHANCE THE EPIDERMAL ANTIMICROBIAL RESPONSE TO LIPOPOLYSACCHARIDE.
Liu1, L., Roberts2, A. A., and Ganz1, T.
1Will Rogers Pulmonary Research Laboratory, Departments of Medicine and Pathology. 2Department of Pathology, Geffen School of Medicine, University of California, Los Angeles, CA 90095.
The Journal of Immunology, 170; 575-580, (2003).
|
307. |
|
ASSESSMENT OF THE IN-HOUSE PERFORMANCE OF THE EPIDERM™ AND EPISKIN™ IN VITRO CORROSIVITY TESTS.
Jones, P. and King , A.
Safety and Environmental Assurance Centre, Unilever Colworth, Sharnbrook, Bedford, MK44 1LQ, U.K.
Presented at Eurotox 2003, Florence Italy, September 28-October 1, (2003).
|
306. |
|
A TIERED STRATEGY FOR IN VITRO PHOTOTOXICITY TESTING.
King, A. and Jones, P.
Safety and Environmental Assurance Centre, Unilever Colworth, Sharnbrook, Bedford, U.K.
Presented at EuroTox, Florence, Italy, September 28-October 1 (2003).
|
304. |
|
STUDIES OF BYSTANDER EFFECTS IN ARTIFICIAL HUMAN 3D TISSUE SYSTEMS USING A MICROBEAM IRRADIATION.
Belyakov, O.V., Hall, E.J., Marino, S.A., Randers-Pehrson, G., Brenner, D.J.
Columbia University, Irvington, NY. Center for Radiological Research
(Annual Report), (2002).
|
303. |
|
GENE EXPRESSION PROFILE OF TISSUE ENGINEERED SKIN SUBJECTED TO ACUTE BARRIER DISRUPTION.
Koria1, P., Brazeau2, D., Kirkwood3, K., Hayden4, P., Klausner4, M., Andreadis1, S.
1Department of Chemical Engineering, University at Buffalo, State University of New York, Amherst, NY, 2Department of Pharmaceutical Sciences, University at Buffalo, State University of New York, Amherst, NY, 3Department of Periodontics and Endodontics, University at Buffalo, State University of New York, Amhert, NY, 4MatTek Corportation, Ashland, MA.
J. Investigative Dermatology, 121, (2), 368-382, (2003).
|
301. |
|
IN HUMAN EPIDERMIS, BETA-DEFENSIN 2 IS PACKAGED IN LAMELLAR BODIES.
Oren1,2, A., Ganz1, T., Liu1, L., Meerloo3, T.
1Geffen School of Medicine at University of California, Los Angeles, CA, 2Veterans Administration Medical Center West Los Angeles, Los Angeles, CA, 3University of California at San Diego School of Medicine, San Diego, CA.
Experimental and Molecular Pathology, 74, 180-182, (2003).
|
299. |
|
ASSESSMENT OF HUMAN SKIN IRRITATION: VALIDATION OF IN VITRO MODELS.
MatTek Scientific, Marketing Staff.
MatTek Corporation, Ashland, MA (USA).
May 2003.
|
297. |
|
EVIDENCE THAT NITRIC OXIDE IS AN UPSTREAM MEDIATOR OF FASL-MEDIATED KERATINOCYTE APOPTOSIS IN TOXIC EPIDERMAL NECROLYSIS.
Viard-Leveugle, I., Saurat, J-H., French, L.E.
Dermatology, Geneva University Hospital, Geneva , CH.
J. Invest. Dermatol., 121, (1), Abstract #743, (2003).
|
296. |
|
NOTCH-1 MEDIATED SIGNALING INCREASES IKKα LEVELS - A CRITICAL DETERMINANT CONTROLLING KERATINOCYTE TERMINAL DIFFERENTIATION AND CELL SURVIVAL.
Chaturvedi, V., Qin, J.Z., Denning, M.F., Miele, L., Nickoloff, B.
Pathology, Loyola University Chicago, Maywood, IL, USA.
J. Invest. Dermatol., 121, (1), Abstract #493, (2003).
|
294. |
|
IN VITRO PERCUTANEOUS ABSORPTION USING THE MATTEK EPI-606X SKIN CONSTRUCT AND HUMAN SKIN.
Klausner1, M., Bagley3, D., Harbell2, J., Kubilus1, J., Moyer2, G., Pugh3, G., Raabe2, H.
1MatTek Corp., 2Institute for In Vitro Sciences, 3Colgate-Palmolive Co.
J. Invest. Dermatol., 121, (1), Abstract #574, (2003).
|
290. |
|
COMPARISON OF IN VITRO MODELS OF PERCUTANEOUS ABSORPTION.
Pugh1, G., Raabe2, H., Moyer2, G., Harbell2, J., Bagley1, D.
1Colgate-Palmolive Company, Piscataway, NJ, USA, 2Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA.
The Toxicologist, 72, S1, 380 (2003).
|
289. |
|
REGULATION OF ANGIOGENESIS FACTORS BY ULTRAVIOLET RADIATION OR HYDROGEN PEROXIDE IN THE EPIDERM IN VITRO SKIN EQUIVALENT.
Last, T.J., Kubilus, J., Klausner, M., Sheasgreen, J. and Hayden, P.
MatTek Corp., Ashland, MA.
The Toxicologist, 72, S1, 222 (2003).
|
288. |
|
USE OF PROTEOMIC TECHNOLOGIES FOR DISCOVERY OF NEW MARKERS OF SKIN IRRITATION IN VITRO.
Fletcher1, S.T., and Baker2, V.A.
1Safety & Environmental Assurance Centre, Unilever, Bedfordshire, U.K. 2CuDoS Cellular Development Systems Ltd, BioCity Nottingham, U.K.
The Toxicologist, 72, S1, 13 (2003).
|
284. |
|
JAGGED-1 MEDIATED ACTIVATION OF NOTCH SIGNALING INDUCES COMPLETE MATURATION OF HUMAN KERATINOCYTES THROUGH NF-B AND PPARγ.
Nickoloff, B.J., Qin, J., Chaturvedi, V., Denning, M., Bonish, B., and Miele, L.,
Department of Pathology, Loyola University Medical Center, Cardinal Bernardin Cancer Center, IL 60153, USA.
Cell Death and Differentiation 9, 842-855 (2002).
|
283. |
|
RECONSTRUCTED SKIN KITS: REPRODUCIBILITY OF CUTANEOUS IRRITANCY TESTING.
C. Faller, M. Bracher.
Cosmital SA (Research Company of Wella AG, Germany), Marly, Switzerland.
Skin Pharmacology and Applied Skin Physiology 2002;15 (Suppl. 1):74-91.
|
282. |
|
NAD(P)H:QUINONE REDUCTASE ACTIVITY IN HUMAN EPIDERMAL KERATINOCYTES AND RECONSTRUCTED EPIDERMAL MODELS.
Harris, I.R., Siefken, W., Beck-Oldach, K., Wittern, K.P., Pollet, D.
Paul Gerson Unna-Skin Research Center, Beiersdorf AG, Hamburg, Germany.
Skin Pharmacology and Applied Skin Physiology, 15,(Suppl1),68-73.
|
281. |
|
COMPARISON OF ACTIVITIES DEPENDENT ON GLUTATHIONE S-TRANSFERASE AND CYTOCHROME P-450 IA1 IN CULTURED KERATINOCYTES AND RECONSTRUCTED EPIDERMAL MODELS.
Harris, I.R., Siefken, W., Beck-Oldach, K., Brandt, M., Wittern, K.P., Pollet, D.,
Paul Gerson Unna-Skin Research Center, Beiersdorf AG, Hamburg, Germany.
Skin Pharmacology and Apploed Skin Physiology, 15,(Suppl1), 59-67.
|
280. |
|
COMPARISON OF CUTANEOUS BIOAVAILABILITY OF COSMETIC PREPARATIONS CONTAINING CAFFEINE OR ALPHA-TOCOPHEROL APPLIED ON HUMAN SKIN MODELS OR HUMAN SKIN EX VIVO AT FINITE DOSES.
Dreher, F., Fouchard, F., Patouillet, C., Andrian, M., Simonnet, J., Benech-Kieffer, F.
L'Oreal Research, Aulnay-sous-Bois, France.
Skin Pharmacology and Applied Skin Physiology, 15, (Suppl 1), 40-58, (2002).
|
279. |
|
IMPROVEMENT OF THE EXPERIMENTAL SETUP TO ASSESS CUTANEOUS BIOAVAILABILITY ON HUMAN SKIN MODELS: DYNAMIC PROTOCOL.
Dreher F., Patouillet C., Fouchard F., Zanini M., Messager A., Roguet R., Cottin M., Leclaire J., Benech-Kieffer F.
L'Oreal Research, Aulnay-sous-Bois, France.
Skin Pharmacology and Applied Skin Physiology, 15, (Suppl 1), 31-9(2002).
|
278. |
|
PERMEATION AND SKIN ABSORPTION: REPRODUCIBILITY OF VARIOUS INDUSTRIAL RECONSTRUCTED HUMAN SKIN MODELS.
Lotte, C., Patouillet, C., Zanini, M., Messager, A., Roguet, R.,
Advanced Research Laboratories, L'Oreal Life Sciences, Aulnay-sous-Bois, France.
Skin Pharmacology and Applied Skin Physiology, 15(suppl 1),18-30, (2002).
|
277. |
|
CHARACTERIZATION OF RECONSTRUCTED SKIN MODELS.
Ponec, M., Boelsma, E., Gibbs, S., Mommaas, M.,
Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands.
Skin Pharmacology and Applied Skin Physiology, 15 (Suppl 1), 4-17, (2002).
|
276. |
|
THE USE OF STANDARDIZED HUMAN SKIN MODELS FOR CUTANEOUS PHARMACOTOXICOLOGY STUDIES.
Roguet, R.,
L'Oreal, Life Sciences, Advanced Research Laboratories, Clichy, France.
Skin Pharmacology and Applied Skin Physiology, 15,(Suppl 1),1-3,(2002).
|
275. |
|
RECONSTRUCTED HUMAN EPIDERMIS EQUIVALENTS.
Roguet1, R., Bracher2, M., Diembeck3, W., Ponec4, M.
1L'Oreal, Life Sciences, Advanced Research Laboratories, Clichy, France, 2Cosmital SA (Research Company of Wella AG, Germany), Marly, Switzerland. 3Beiersdorf AG, Hamburg, Germany, 4Humboldt University, Berlin, Germany. 4Department of Dermatology, University Hospital, Leiden, The Netherlands.
Skin Pharmacology and Applied Skin Physiology, 15,(Suppl1)I-III (2002).
|
274. |
|
BARRIER FUNCTION COMPARISON BETWEEN IN VITRO SKIN, ORAL (BUCCAL), AND OCULAR TISSUE MODELS - IMPLICATIONS FOR DRUG DELIVERY STUDIES.
Klausner1, M., Kubilus1, J., Song2, Y., Michniak2, B.,
1Department of Research and Development, MatTek, Ashland, MA, 2Department of Pharmacology and Physiology, UMDNJ-NJMS, Newark, NJ.
Presented at the American Association of Pharmaceutical Scientists Meeting, November (2002).
|
273. |
|
NALTREXONE ESTER PRODRUG BIOCONVERSION IN A HUMAN EPIDERMIS EQUIVALENT.
Stinchcomb1, A., Hammell1, D., Challapalli1, P., Paxton1, E., Swaan2, P., Klausner3, M.,
1University of Kentucky College of Pharmacy, Lexington, KY, 2The Ohio State University College of Pharmacy, Columbus, OH, 3MatTek Corporation, Ashland, MA.
Presented at the American Association of Pharmaceutical Scientists Meeting, November (2002).
|
272. |
|
IMPROVEMENTS IN EPIDERM, A HIGHLY DIFFERENTIATED SKIN MODEL, FOR DRUG DELIVERY STUDIES
Song1, Y., Klausner2, M., Kubilus2, J., Michniak1, B.,
1Department of Pharmacology and Physiology, UMDNJ-NJMS, Newark, NJ, 2Department of Research and Development, MatTek Corporation, Ashland, MA.
Presented at the American Association of Pharmaceutical Scientists Meeting, Toronto, Canada. November 10-14, (2002).
|
270. |
|
PREDICTIVE ABILITY OF RECONSTRUCTED HUMAN EPIDERMIS EQUIVALENTS FOR THE ASSESSMENT OF SKIN IRRITATION OF COSMETICS.
1Faller, C., 1Barcher, M., 2Dami, N., 2Roguet, R.,
1Cosmital SA (Research Company of Wella AG, Germany), Rte de Chesalles 21, CH-I723 Marly, Switzerland. 2L'Oreal, Life Sciences Research Centre, C. Zviak, rue du General Roguet 90, 92583 Clichy Cedex, France.
Toxicology In Vitro, 16, 557-572, (2002).
Article Summary
|
269. |
|
EVALUATION OF RECONSTRUCTED HUMAN EPIDERMIS KITS FOR THE IN VITRO ASSESSMENT OF COSMETIC SAFETY.
1Roguet R., 3Faller, C., 1Dreher, F., 1Lotte, C., 2Harris, I., 3Bracher, M., 2Pollet, D., 2Pfannenbecker, U., 1Dami, N., 4Ponec, M.,
1L'OREAL Life Sciences Research, France, 2BEIERSDORF AG, R&D Cosmed, Germany, 3WELLA/COSMITAL Department of in Vitro Toxicology, Switzerland, 4University of Leiden, Department of Dermatology, The Netherlands.
Presented at Scandinavian Society of Cosmetic Chemists, Stockholm, Sweden, May (2001).
|
268. |
|
USE OF DIFFERENTIAL DISPLAY-POLYMERASE CHAIN REACTION TO IDENTIFY GENES SELECTIVELY MODULATED BY CHEMICAL ALLERGENS IN RECONSTITUTED HUMAN EPIDERMIS.
1Corsini, E., 2Sheasgreen, J., 1Marmovich, M., and 1Galli, C.,
1Laboratory of Toxicology, Department of Pharmacological Sciences, University of Milan, Milan, Italy, 2MatTek Corporation, Ashland, MA, USA.
Toxicology in Vitro,16,427-431, (2002).
|
265. |
|
PROTEOMIC AND MICROARRAY INVESTIGATION TO IDENTIFY POTENTIAL IN VITRO ENDPOINTS FOR SKIN IRRITATION.
Fletcher1, S.T., Fentem1, J.H., Basketter1, D.A., Kelsell2, M.Philpott2, D.P., and Baker1, V.A.
1SEAC Toxicology, Unilever R&D, Colworth, Bedfordshire, U.K. 2Centre for Cutaneous Research, QMW, University of London, U.K.
Presented at the Annual Meeting of the Society of Investigative Dermatology, Los Angeles, CA, May 15-18, (2002).
|
261. |
|
USE OF EPIDERM™ AS AN INFLAMMATORY MODEL FOR PRE-CLINICAL SCREENING.
Last, T.J., Hayden, P., Burnham, B., Klausner, M., Kubilus, J.
MatTek Corporation, Ashland, MA.
Presented at Soc. Invest. Derm. Meeting, May (2002).
|
260. |
|
EXPRESSION OF CYCLOOXYGENASE IN THE EPIDERM™ HUMAN SKIN MODEL: REGULATION BY ULTRAVIOLET RADIATION AND CYTOKINES.
Hayden, P.J., Last, T.J., Burnham, B., Klausner, M.
MatTek Corporation, Ashland MA.
Presented at Soc. Invest. Derm. Meeting, May (2002).
|
258. |
|
IDENTIFICATION OF POTENTIAL IN VITRO ENDPOINTS FOR SKIN IRRITATION USING PROTEOMIC AND MICROARRAY ANALYSIS.
Fletcher1, S.T., Fentem1, J.H., Basketter1, D.A., Kelsell2, D.P., Philpott2, M., Baker1, V.A.
1SEAC, Unilever, Bedfordshire, United Kingdom , 2Centre for Cutaneous Research, Queen Mary, University of London, United Kingdom.
The Toxicologist, 66 (1-S), 222, Soc. of Toxicol. (Reston, VA), Abstract #1090, (2002).
|
257. |
|
HUMAN β-DEFENSIN-2 PRODUCTION IN KERATINOCYTES IS REGULATED BY INTERLEUKIN-1, BACTERIA, AND THE STATE OF DIFFERENTIATION.
Liu, A., Destoumieux, D., Wong, A., Park, C., Valore, E., Liu, L., Ganz, T.
UCLA School of Medicine.
J. Invest. Dermatol., 118, (2), 275-281, (2002).
|
254. |
|
NEW PERSPECTIVES ON SKIN-COMPATIBLE DETERGENTS FOR SENSITIVE SKIN.
Kremer1, J., Matthies1, W. and Voigtmann2, I.
1Henkel KGaA, Henkelstr. 67, 40191 Dusseldorf. 2Deutscher Allergie- und Asthmabund e. V., Hindenburgstr. 110, 41061 Monchengladbach.
14th Lecture Conference of the GDCH Section "Waschmittelchemie", Wurzburg, Germany, April (2000).
|
252. |
|
ACTIVATION OF NOTCH SIGNALING IN KERATINOCYTES (KC'S) IS NECESSARY AND SUFFICIENT TO CREATE MATURE HUMAN EPIDERMIS.
Nickoloff, B.J., Qin, J., Chaturvedi, V., Denning, M., Banish, B., and Miele, L.
Pathology, Loyola University Chicago, Maywood, IL, USA.
J. Invest. Dermatol., 117, (2), 408, Abstract #110, (2001).
|
251. |
|
CROSS-TALK BETWEEN NOTCH SIGNALING AND TWO PATHWAYS REGULATING EPIDERMAL DIFFERENTIATION.
Chaturvedi, V., Qin, J., Miele, L. and Nickoloff, B.J.
Pathology, Loyola University Chicago, Maywood, IL, USA.
J. Invest. Dermatol., 117, (2), 409, Abstract #116, (2001).
|
250. |
|
CHARACTERIZATION OF APOPTOTIC MACHINERY CONTROLLING CELL DEATH IN EPIDERMIS.
Qin, J.Z., Chaturvedi, V., Denning, M.F., and Nickoloff, B.J.
Pathology, Loyola University Medical Center, Maywood, IL, USA.
J. Invest. Dermatol., 117, (2), 404, Abstract #85, (2001).
|
249. |
|
THE PROTEASE-ACTIVATED RECEPTOR 2 REGULATES PIGMENTATION VIA KERATINOCYTE-MELANOCYTE INTERACTIONS.
Seiberg, M., Paine, C., Sharlow, E., Andrade-Gordon, P., Costanzo, M., Eisinger, M., Shapiro, S.S.
Skin Research Center, Johnson & Johnson CPWW, Skillman, New Jersey, 08558, USA.
Exp. Cell Res., 254(1), 25-32, (2000).
|
247. |
|
APPROACHES FOR THE DEVELOPMENT OF CELL-BASED IN VITRO METHODS FOR CONTACT SENSITIZATION.
Ryan, C.A., Hulette, B.C., Gerberick, G.F.
The Procter & Gamble Company, Miami Valley Laboratories, PO Box 538707, Cincinnati, OH 45253-8707.
Toxicology In Vitro, 15, 43-55, (2001).
|
245. |
|
THE INFLUENCE OF COSMETIC PRODUCTS ON THE STRATUM CORNEUM BY INFRARED AND RAMAN SPECTROSCOPY.
Prasch, Th., Schlotmann, K., Schmidt-Fonk, K., and Forster, Th.
Henkel KGaA, Dusseldorf, Germany.
IFSCC Magazine, 4(3), 201-206, (2001).
|
241. |
|
GENE EXPRESSION ANALYSIS OF EPIDERM™ FOLLOWING EXPOSURE TO SLS USING cDNA MICROARRAYS.
Fletchera, S.T., Bakera, V.A., Fentema, J.H., Baskettera, D.A., Kelsellb, D.P.
aSEAC Toxicology Unit, Unilever Research, Sharnbrook, Bedfordshire MK44 1LQ, UK. bCentre for Cutaneous Research, St Bartholomews and The Royal London School of Medicine and Dentistry, Queen Mary and Westfield College, 2 Newark Street, London E1 2AT, UK.
Toxicology in Vitro, 15, 393-398, (2001).
|
240. |
|
EFFECTS OF CEES ON INFLAMMATORY MEDIATORS, HEAT SHOCK PROTEIN 70A, HISTOLOGY AND ULTRASTRUCTURE IN TWO SKIN MODELS.
Blaha, M., Jr., Bowers, W., Kohl, I., DuBose, D., Walker, J., Alkhyyat, A., Wong, G.
US Army Research Institute of Environmental Medicine, Natick, MA 01760 USA.
J. Appl. Toxicol., 20, S-1, S101-8, (2000).
|
239. |
|
ULTRASTRUCTURAL AND HISTOLOGICAL EFFECTS OF EXPOSURE TO CEES OR HEAT IN A HUMAN EPIDERMAL MODEL.
Blaha1, M., Kohl1, J., DuBose1, D., Bowers, Jr.1, Walker2, J.
1U.S. Army Research Institute of Environmental Medicine and 2U.S. Army Soldier Systems Center, Natick, Massachusetts 01760.
In Vitro & Molecular Toxicology, 14(1), 15-13, (2001).
|
238. |
|
ASSESSMENT OF HUMAN CADAVER AND RECONSTRUCTED SKIN MODELS TO PREDICT PHARMACOKINETICS OF TESTOSTERONE TRANSDERMAL DRUG DELIVERY PATCHES.
Myszka1, S.L.W., Husberg1, M.L., Lawton1, J.M., Lippert1, D.R., Harrison2, L.I.
13M Drug Delivery Systems Division, St. Paul, MN, USA, 55144, 23M Pharmaceuticals Division, St. Paul, MN, USA, 55144.
Presented at The 28th International Symposium on Controlled Release of Bioactive Materials, San Diego, CA, USA June 23-27, (2001).
|
237. |
|
DEVELOPMENT OF AN IN VITRO METHOD FOR SKIN CORROSION TESTING.
Perkins, M.A., Osborne, R., Johnson, O.R.
Procter and Gamble Company.
Fundam. Appl. Toxicol., 31(1), 9-18, (1997).
|
236. |
|
RECONSTITUTED 3-DIMENSIONAL HUMAN SKIN AS A NOVEL IN VITRO MODEL FOR STUDIES OF CARCINOGENESIS.
Zhao, J.F., Zhang, Y.J., Kubilus, J., Jin, X.H., Santella, R.M., Athar, M., Wang, Z.Y., Bickers, D.R.
Biochem. Biophys. Res. Commun., 254(1), 49-53 (1999).
|
235. |
|
EXPRESSION OF PLACENTA GROWTH FACTOR
CYCLOOXYGENASE AND THYMUS-AND ACTIVATION-REGULATED CHEMOKINE IN THE EPIDERM IN VITRO HUMAN SKIN EQUIVALENT.
Hayden, P., Last, T.J., Klausner, M., Kubilus, J.
MatTek Corp. Ashland, MA 01721.
J. Invest. Dermatol., 117, (2), 471, Abstract #490, (2001).
|
234. |
|
MICROARRAY ANALYSIS OF GENE EXPRESSION FOLLOWING EXPOSURE TO SKIN IRRITANTS.
Fletcher, S., Baker, V., Fentem, J., Basketter, D., Kelsell*, D.
SEAC Toxicology, Unilever Research, Shambrook, United Kingdom; *Centre for Cutaneous Research, Queen Mary and Westfield College, London, United Kingdom.
J. Invest. Dermatol., 117, (2) 528, Abstract #832, (2001).
|
233. |
|
TOPICALLY APPLIED LACTIC ACID INCREASES SPONTANEOUS SECRETION OF VASCULAR ENDOTHELIAL GROWTH FACTOR BY HUMAN RECONSTRUCTED EPIDERMIS.
Rendl1, M., Mayer1, C., Weninger1,2, W., Tschachler1,3, E.
1Division of Immunology, Allergy and Infectious Diseases, Department of Dermatology, University of Vienna Medical School, Währinger Gürtel 18–20, A-1090 Vienna, Austria. 2Center for Blood Research, Department of Pathology, Harvard Medical School, Boston, MA, U.S.A. 3Centre de Recherches et Investigation Epidermiques et Sensorielles, Neuilly, France.
British Journal of Dermatology, 145(1), 3-9, (2001).
|
232. |
|
INTERRELATION OF PERMEATION AND PENETRATION PARAMETERS OBTAINED FROM IN VITRO EXPERIMENTS WITH HUMAN SKIN AND SKIN EQUIVALENTS.
Wagner1, H., Kostka2 K-H., Lehr1, C-M., Schaefer1, U.F.
1Department of Biopharmaceutics and Pharmaceutical Technology, Saarland University, D-66123 Saarbruecken, Germany. 2Department of Plastic and Hand Surgery, Caritaskrankenhaus, D-66822 Lebach, Germany.
Journal of Controlled Release, 75(3), 283-295, (2001).
|
231. |
|
COMPARISON OF CUTANEOUS BIOAVAILABILIY OF COSMETIC PREPARATIONS CONTAINING CAFFEINE OR α-TOCOPHEROL APPLIED ON HUMAN SKIN MODELS OR HUMAN SKIN EX VIVO AT FINITE DOSES.
Dreher1, F., Fouchard1, F., Patouillet1, C., Andrian1, M., Simonnet2, J-T., Benech-Kieffer1, F.
1Life Sciences, L'OREAL advanced Research Laboratories, Aulnay-sous-BoisFrance, 2L'OREAL Applied Research, Chevilly-Larue France.
Presented at Gordon Research Conference on "Barrier Function of Mammalian Skin", Bristol, USA, August 5-10, (2001).
|
230. |
|
APPLICATION OF A HUMAN SKIN TISSUE CULTURE MODEL IN DERMAL ABSORPTION STUDIES OF 3,3’,4,4-TETRACHLOROBIPHENYL (TCB).
Oiao1, G.L., Riviere2, J.E.
1Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV. 2Center for Cutaneous Toxicology and Residue Pharmacology, North Carolina State University, Raleigh, NC, USA.
The Toxicologist, 54 (1), 150, Soc. of Toxicol. (Reston, VA), Abstract #707, (2000).
|
229. |
|
AVOCADO PHYTOSTEROLS DECREASE UVB-INDUCED PRO-INFLAMMATORY MEDIATORS.
Joseph, L.B., Koukouras, K.
Croda, Inc., NATC, Edison, NJ.
J. Invest. Dermatol., 117, (2), 501, Abstract #667, (2001).
|
228. |
|
AN IN VITRO METHOD FOR SCREENING ANTI-IRRITANTS ON UV AND CHEMICALLY TREATED, RECONSTITUTED, THREE DIMENSIONAL HUMAN SKIN.
Majmudar, G., Fisher, L.
Mary Kay Holding Corp., Dallas, Texas.
J. Invest. Dermatol., 117, (2), 459, Abstract #415, (2001).
|
224. |
|
EVALUATION OF THE USEFULNESS OF 3-D MODELS OF RECONSTITUTED HUMAN SKIN AND EPIDERMIS IN APPLICATIONS OF REGULATORY SKIN TOXICOLOGY: PREVALIDATION, VALIDATION, CATCH-UP VALIDATION, AND REGULATORY ACCEPTANCE.
Liebsch, M.
ZEBET BgVV, National Center for Evaluation and Validation of Alternatives to Animal Experiments, D-12277, Berlin, Germany.
In Vitro Cell. Dev. Biol – Animal, 37, (3), (2001).
|
223. |
|
HUMANE ENDPOINTS AND ACUTE TOXICITY TESTING.
Sass, N.
Alabama Department of Public Health, Montgomery, Alabama, USA.
ILAR Journal, 41(2), 14-23, (2000).
|
222. |
|
IN VITRO AND HUMAN TESTING STRATEGIES FOR SKIN IRRITATION.
Robinson, M.K., Osborne, R., Perkins, M.A.
The Procter & Gamble Company, Miami Valley Laboratories, Cincinnati, Ohio 45253-8707.
Ann. NY Acad. Sci., 919, 192-204 (2000).
|
221. |
|
RECONSTRUCTED SKIN EQUIVALENTS FOR ASSESSING PERCUTANEOUS DRUG ABSORPTION FROM PHARMACEUTICAL FORMULATIONS.
Zghoul, N., Fuchs, R., Lehr, C.M., Schaefer, U.F.
Dept. of Biopharmaceutics and Pharmaceutical Technology, Saarland University, D-Saarbrucken.
Altex, 18(2), 103-6, (2001).
|
219. |
|
STRATEGIES FOR THE ASSESSMENT OF ACUTE SKIN IRRITATION POTENTIAL.
Robinson, M., Osborne, R., Perkins, M.A.
Procter & Gamble Co., Miami Valley Labs, PO Box 538707, Cincinnati Ohio 45253-8707
Journal of Pharmacological and Toxicological Methods, 42, 1-9, (1999).
|
217. |
|
EFFECTS OF ANTIOXIDANT INGREDIENTS ON HUMAN SKIN: FROM CELL CULTURE TESTING TO HUMAN CLINICAL TRIALS.
Green1, J., Roberts2, R.
1Shaklee Corporation, Hayward, CA and 2R.L. Roberts and Associates, Germantown, TN.
Journal of Cosmetic Science, 51, (1) 42-43, (2000).
|
216. |
|
EVALUATION OF HUMAN BIO-ENGINEEREED SKIN EQUIVALENT FOR DRUG PERMEATION STUDIES.
Asbill, C., Kim, N., El-Kattan, A., Creek, K., Wertz, P., Michniak, B.
Department of Basic Pharmaceutical Science, College of Pharmacy, University of South Carolina.
Pharmaceutical Research, 17, (9) 1092-7, (2000).
|
215. |
|
PERCUTANEOUS PERMEATION OF ZINC FROM NON-WOVEN FABRICS IMPREGNATED WITH ZINC SULFATE MONOHYDRATE FORMULATIONS USING EPIDERM™.
El-Kattan, A., Michniak, B.
Department of Basic Pharmaceutical Science, College of Pharmacy, University of South Carolina.
Presented at the 6th World Biomaterials Congress in Kumuela, Hawaii, May 15-20, (2000).
|
214. |
|
LIPID AND ULTRA-STRUCTURAL CHARACTERIZATION OF RECONSTRUCTED SKIN MODEL.
Ponec, M., Boelsma, E., Weerheim, A., Mulder, A., Bouwstra, J., Mommaas, M.
Leiden University, Leiden, The Netherlands
International J. of Pharmaceutics, 203, 211-225, (2000).
|
213. |
|
RECONSTRUCTED HUMAN SKIN EQUIVALENTS-THEIR VALUE FOR SCREENING OF SKIN IRRITATION.
Esther Boelsma
Thesis University Leiden, Leiden, The Netherlands.
ISBN 90-9012744-5, (1999).
|
212. |
|
IN VITRO TESTING FOR PHOTOTOXIC POTENTIAL USING THE EPIDERM 3-D RECONSTRUCTED SKIN MODEL.
Jones, P., Lovell, W., King, A., Earl, L.
Unilever Research.
Toxicology Methods, 11, (1) 1-19, (2001).
|
210. |
|
HIGHLY DIFFERENTIATED SKIN EQUIVALENT MODEL FOR HIGH THROUGHPUT SCREENING OF TOPICAL THERAPEUTICS.
Hayden, P., Jackson, R., Klausner M., Kubilus, J.
MatTek Corp., Ashland, MA.
J. Invest. Dermatol., 115, (3) 589, Abstract #359, (2001).
|
209. |
|
A REPRODUCIBLE SKIN MODEL FOR DERMAL SAFETY AND EFFICACY TESTING.
Klausner, M., Kubilus, J., Hayden, P., Sheasgreen, J.
MatTek Corp., Ashland, MA.
The Toxicologist, 60 130, Soc. of Toxicol. (Reston, VA), Abstract #622, (2001).
|
208. |
|
RANTES, GRO-α, TNF-α RELEASE FROM IN VITRO EPIDERMIS MODELS FOLLOWING TREATMENT OF STAPHLOCOCCAL ENTEROTOXIN A.
Yamada, H., Yudate, T., Matukura, M., Tezuka, T.
University School of Medicine, Osaka, Japan.
Presented at the 22nd Annual Meeting of the Japanese Soc. for Investigative Dermatology, Osaka, Japan, September 4-5, (1997).
Online.
|
207. |
|
DERMATACS™ IN SITU APOTOSIS DETECTION KIT FOR SKIN CELLS AND TISSUES.
Trevigen, Inc.
Trevigen Press Release (2000).
Online: DermaTACS.
|
205. |
|
A REPRODUCIBLE, STRUCTURALLY APPROPRIATE SKIN MODEL FOR DERMAL SAFETY AND EFFICACY TESTING.
Klausner, M., Sheasgreen, J., Hayden, P., Liebsch1, M., Kubilus, J.
MatTek Corp., Ashland, MA, 01721, USA; 1ZEBET, Berlin, Germany.
Presented at the 21st International Federation of Societies of Cosmetic Chemists Congress, Berlin, Germany, September 11 – 14, (2000).
|
204. |
|
TERMINAL DIFFERENTIATION OF HUMAN KERATINOCYTES AND STRATUM CORNEUM FORMATION IS ASSOCIATED WITH CASPASE-14 ACTIVATION.
1Eckhart, L., Declercq2, W., Ban1, J., Rendl1, M., Mayer1, C., Lippens2, S., Vandenabeele2, P., Tschachler1,3, E.
1Division of Immunology, Allergy and Infectious Diseases, Department of Dermatology, University of Vienna Medical School, Vienna, Austria, 2Molecular Signaling and Cell Death Unit, Department of Molecular Biology, Flanders Interuniversity Institute for Biotechnology and Gent University, Gent, Belgium. 3Centre de Recherches et d’Investigations Epidermiques et Sensorielles (CE.R.I.E.S.), Neuilly, France.
J. Invest. Dermatol., 115, (6), 1148-1151, (2000).
|
203. |
|
IL-1-RELATED CYTOKINE RESPONSES OF NONIMMUNE SKIN CELLS SUBJECTED TO CEES EXPOSURE WITH AND WITHOUT POTENTIAL VESICANT ANTAGONISTS.
Blaha1, M., Bowers, Jr.1, W., Kohl1, J., DuBose1, D., Walker2, J.
1U.S. Army Research Institute of Environmental Medicine. 2U.S. Army Soldier and Biological Chemical Command, Natick, MA 01760.
In Vitro & Molecular Toxicology, 13, (2), 99, (2000).
|
201. |
|
RECONSTRUCTED EPIDERMAL MODELS AS A POSSIBLE ALTERNATIVE TO THE USE OF EXCISED HUMAN SKIN FOR ASSESSING IN VITRO PERCUTANEOUS ABSORPTION.
Zghoul, N., Wagner, H., Lehr, C-M., Schaefer, U.
Department of Biopharmaceutics and Pharm. Technology, Saarland University D-66123 Saarbruecken, Germany.
|
199. |
|
CHARACTERIZATION AND COMPARISON OF RECONSTRUCTED SKIN MODELS: MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL EVALUATION.
Boelsma1, E., Gibbs1, S., Faller 2, C., Ponec1, M.
1Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands and 2Department of In Vitro Toxicology, Laboratory of Cytotoxicity and Irritation, COSMITAL SA, Marly, Switzerland
Acta Derm Venereol, 80, 82-88, (2000).
|
198. |
|
INHIBITION OF UV INDUCED MMP-1 IN EPIDERMAL EQUIVALENTS BY ANTIOXIDANTS.
Martin, K.M., Lyte, P., Mazuruk, K., Shapiro, S.
Skin Research Center, Johnson & Johnson Consumer Products Worldwide, Skillman, New Jersey.
J. of Invest. Dermatol., 114, 803, Abstract #309, (2000).
|
197. |
|
CHANGES IN CANCER-RELATED GENE EXPRESSION IN AN IN VITRO HUMAN SKIN MODEL FOLLOWING UVB-IRRADIATION.
Hayden, P.J., Klausner, M., Kubilus, J.
MatTek Corp., Ashland, Massachusetts
J. of Invest. Dermatol., 114, 824, Abstract #449, (2000)
|
195. |
|
USE OF DIFFERENTIATED EPIDERMAL CULTURES FOR THE EXAMINATION OF INFANT-FECES-INDUCED SKIN IRRITATION.
Hendrix, S.W.
Procter and Gamble, Cincinnati, Ohio.
J. of Invest. Dermatol., 114, 836, Abstract #519, (2000).
|
194. |
|
WOUNDING UPREGULATES VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION BY KERATINOCYTES OF IN VITRO RECONSTRUCTED HUMAN EPIDERMIS.
Rendl, M., Mayer, C., Fischer, H., Pammer*, J., Weninger, W., Tschachler, E.
DIAID, Department of Dermatology, University of Vienna Medical School, Vienna, Austria, *Institute of Clinical Pathology, University of Vienna Medical School, Vienna, Austria
J. of Invest. Dermatol., 114, 855, Abstract #636, (2000).
|
193. |
|
LACK OF PHOTOTOXICITY OF COSMETIC FORMULATIONS CONTAINING GLYCOLIC ACID IN AN IN VITRO HUMAN SKIN MODEL.
Jones1, B.C., Raabe2, H.A., Sizemore2, A., Mun2, G.C., Theophilus1, E.H., Dickens1, M.S.
1Avon Products, Inc., Suffern, NY, 2Institute for In Vitro Sciences, Inc., Gaithersburg, MD
Toxicological Sciences, 54, (1), 394-5, Abstr. #1853 (2000).
|
192. |
|
PREVALIDATION OF THE EPIDERM PHOTOTOXICITY TEST (ED-PT).
Liebsch1, M., Traue1, D., Barrabas1, C., Spielmann1, H., Gerberick2, F., Cruse2, L., Diembeck3, W., Pfannenbecker3, U., Spieker3, J., Hottzhutter3, H., Brantom5, P., Aspin5, P., Southee6, J.
1ZEBET BgVV, Berlin, Germany, 2Procter & Gamble Co., Cincinnati, OH, 3Beiersdorf AG, Hamburg, Germany, 4Humboldt University, Berlin, Germany, 5BIBRA International, Carshalton, United Kingdom, 6MA Bioservices, Richmond, United United Kingdom
Toxicological Sciences, 54, (1), 379, Abstr. #1777 (2000).
|
189. |
|
HIGHLY DIFFERENTIATED IN VITRO SKIN MODEL FOR HIGH THROUGHPUT SCREENlNG OF TOPICAL THERAPEUTICS.
Hayden, P.J., Jackson, Jr., G.R., Klausner, M., Kubilus, J.
MatTek Corp., Ashland, MA 01721.
Toxicological Sciences, 54, (1), 146, Abstr. #688 (2000).
|
188. |
|
THE PROTEASE-ACTIVATED RECEPTOR 2 REGULATES PIGMENTATION VIA KERATINOCYTE-MELANOCYTE INTERACTIONS.
Seiberg, M., Paine, C., Sharlow, E., Andrade-Gordon, P., Costanzo, M., Eisinger, M., Shapiro, S.S.
Skin Research Center, Johnson & Johnson CPWW, Skillman, NJ, 08558 USA.
Exp. Cell Res., 254(1), 25-32, (2000).
|
187. |
|
IL-1α AND IL-1ra SECRETION FROM EPIDERMAL EQUIVALENTS AND THE PREDICTION OF THE IRRITATION POTENTIAL OF MILD SOAP AND SURFACTANT-BASED CONSUMER PRODUCTS.
Bernhofer1, L.P., Barkovic2, S., Appa2, Y., Martin1*, K.M.
1Skin Research Center, Johnson & Johnson Consumer Products Worldwide, 199 Grandview Road, Skillman, NJ 08558, 2Neutrogena Corporation, 5760 West 96th Street, Los Angeles, CA 90045, USA.
Toxicology in Vitro, 13, 231-239, (1999).
|
186. |
|
THE INFLUENCE OF THE RESPONSE OF SKIN EQUIVALENT SYSTEMS TO TOPICALLY APPLIED CONSUMER PRODUCTS BY EPITHELIAL-MESENCHYMAL INTERACTIONS.
Bernhofer, L.P., Seiberg, M., Martin, K.M.
Skin Research Center, Johnson & Johnson Consumer Products Worldwide, 199 Grandview Road, Skiliman, NJ 08558, USA.
Toxicology in Vitro, 13, 219-229, (1999).
|
185. |
|
THE EFFECTS OF TROPOSPHERIC OZONE ON A HUMAN EPIDERMAL SKIN MODEL (EPIDERM).
Weber, S.U., Tavakkol*, A., Nabi*, Z., Jothi, S., Polefka*, T.G., Packer, L.
Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California, *Personal Care Products, Colgate-Palmolive Co., Piscataway, New Jersey.
J. Invest. Dermatol., 112, 576, Abstract #323, (1999).
|
184. |
|
ASSESSMENT OF THE IRRITATION POTENTIAL OF TOPICAL SKIN ANTISEPTICS BY IN VIVO AND IN VITRO METHODS.
Azar, C.G., McDonnell, G.E., Pretzer, D.
Steris Corp. P.O.Box 147, St. Louis, MO 63166
Presented at 3rd Annual Symposium International Business Conferences on "In Vitro Testing Methods for Cosmetics", Washington, DC, Nov. 16-17, (1998).
|
182. |
|
THE ECVAM PREVALIDATION STUDY ON THE USE OF EPIDERM FOR SKIN CORROSIVITY TESTING.
Liebsch, M., Traue, D., Barrabas, C., Spielmann, H., Uphill1, P., Wilkins1, S., McPherson1, J., Wiemann2, C., Kaufmann2, T., Remmele2, M., Holzhütter3, H.-G., Brantom4, P., Aspin4, P., Southee5, J.A.
National Center for Documentation and Evaluation of Alternative Methods to Animal Experiments (ZEBET), Federal Institute for Health Protection of Consumers and Veterinary Medicine (Bg VV), Diedersdorfer Weg 1, 12277 Berlin, Germany, 1Huntingdon Life Sciences, Huntingdon, UK, 2BASF AG, Ludwigshafen, Germany, 3Humboldt University, Berlin, Germany, 4BIBRA International, Carshalton, UK, 5Consultant, Richmond, UK.
ATLA, 28, 371, (2000).
|
181. |
|
PREVALIDATION OF THE EPIDERM PHOTOTOXCITY TEST.
Liebsch, M., Traue, D., Barrabas, C., Spielmann, H., Gerberick1, F., Cruse2, L., Diembeck2, W., Pfannenbecker2, U., Spieker2, J., Holzhütter3, H. G., Brantom4, P., Aspin4, P., Southee5, J. A.
National Center for Documentation and Evaluation of Alternative Methods to Animal Experiments (ZEBET), Federal Institute for Health Protection of Consumers and Veterinary Medicine (BgVV), Diedersdorfer Weg 1, 12277 Berlin, Germany, 1Procter & Gamble, Cincinnati, USA, 2Beiersdorf AG, Hamburg, Germany, 3Humboldt University, Berlin, Germany, 4BIBRA International, Carshalton, UK, 5MA Bioservices, Stirling, UK.
ATLA, 27, 301, (1999).
|
180. |
|
HUMAN IN VITRO AND IN VIVO CUTANEOUS RESPONSES TO SOAP SUSPENSIONS: ROLE OF SOLUTION BEHAVIOR IN PREDICTING POTENTIAL IRRITANT CONTACT DERMATITIS.
Warren, R., Sanders, L.M., Curtis, S.L., Wong, L.F., Zhu, C., Tollens, F.R., Otte, T.E.
Sharon Woods Technical Center, The Procter and Gamble Company Cincinnati, OH, 45224-1795.
In Vitro & Molecular Toxicol., 12(2), 97, (1999).
|
179. |
|
TESTING AND IMPROVEMENT OF RECONSTRUCTED SKIN KITS IN ORDER TO ELABORATE EUROPEAN STANDARDS: FIRST RESULTS.
Roguet, R., Beck1, H., Boelsma2, E., Bracher1, M., Faller1, C., Harris2, I., Lotte, C., Dreher, F., Ponec2, M.
L'Oréal, Life Sciences Research, 92583 Clichy, France, 1Department of In Vitro Toxicology, WELLA/COSMITAL, Marly, France, 2Department of Dermatology, University Hospital, Leiden, The Netherlands, 3Department of Molecular Biology, Beiersdorf AG, Hamburg, Germany.
ATLA, 27, 333, (1999).
|
177. |
|
MELANODERM™: AN EPIDERMAL TISSUE MODEL CONTAINING FUNCTIONAL MELANOCYTES.
Klausner, M., Neal, P., Breyfogle, B., Kubilus, J.
MatTek Corp., Ashland, MA 01721, USA.
Presented at the 17th International Pigment Cell Conference, Nagoya, Japan Oct 30-Nov 4, 1999. Also published in ATLA, 27, 299, (1999).
|
175. |
|
ARTIFICIAL HUMAN SKIN: CYTOKINE, PROSTAGLANDIN, HSP7O AND HISTOLOGICAL RESPONSES TO HEAT EXPOSURE.
Bowersa, W., Blahaa, M., Alkhyyata, A., Sankovicha, J., Kohla, J., Wongb, G., Pattersona, D.
aUS Army Research Institute of Environmental Medicine, Military Nutrition and Biochemistry Division, Kansas Street, Natick, MA 01760-5007, USA, bStressGen Biotechnologies Corp., Victoria, BC, Canada V8Z 4B9.
J. of Dermatol. Sci., 20, 172-182, (1999).
|
174. |
|
COMPARISON OF IN VITRO AND IN VIVO HUMAN SKIN RESPONSES TO CONSUMER PRODUCTS AND INGREDIENTS WITH A RANGE OF IRRITANCY POTENTIAL.
Perkins, M.A., Osborne, R., Rana, F.R., Ghassemi, A., Robinson, M.K.
The Procter & Gamble Company, Human and Environmental Safety Division, Miami Valley Laboratories, P O Box 538707, Cincinnati, Ohio 45253-8707.
Toxicological Sciences, 48, 218-229 (1999).
|
172. |
|
PROTECTING THE SKIN AGAINST EXOGENOUS NOXES.
Forster, T., Meister, J., Moller, H., Orlanderl, S., Schlotmann, K.
Henkel KGaA, Dusseldorf, Germany.
Allured's Cosmetics & Toiletries, 114, (3), 71-80, (1999).
|
171. |
|
EPIDERMAL STRATIFICATION REDUCES THE EFFECTS OF UVB (BUT NOT UVA) ON KERATINOCYTE CYTOKINE PRODUCTION AND CYTOTOXICITY.
Corsini2, E., Sangha1, N., Feldman2, S.N.
1Departments of Dermatology and Pathology, Bowman Grey School of Medicine, Wake Forest University, Winston Salem, NC, USA, 2Center for Cosmetic Toxicology, Institute of Pharmacological Sciences, University of Milan, Milan, Italy.
Photodermatol. Photoimmunol. Photomed., 13, 147-152, (1997).
|
170. |
|
DEVELOPMENT OF AN IN VITRO METHOD FOR SCREENING ANTI-IRRITANTS.
Majmudar, G., Smithey, T., Fisher, L.
Mary Kay Holding Corp.
Presented at SCC Annual Scientific Seminar, Chicago, IL, May 6-7, (1999).
|
169A. |
|
ALTERNATIVE METHODS FOR SKIN IRRITATION TESTING: THE CURRENT STATUS.
Botham1, P.A., Earl2, L.K., Fentem3, J.H., Roguet4, R., Van de Sandt5, J.J.M.
1Central Toxicology Laboratory, ZENECA, Alderley Park, Macclesfield, Cheshire SK10 4TJ, UK, 2SEAC Toxicology Unit, Unilever Research, Colworth House, Sharnbrook, Bedford MK44 1LQ, UK, 3ECVAM, JRC Environment Institute, 21020 Ispra (VA), Italy, 4L'Oreal, Life Sciences Research, 1 Avenue Eugene Schueller, 93600 Aulnay-sous-Bois, France, 5TNO Nutrition and Food Research Institute, Toxicology Division, Utrechtseweg 48, 3700 AJ Zeist, The Netherlands.
ATLA, 26, 195-211, (1998).
|
169. |
|
PREVALIDATION OF TESTS FOR PREDICTING SKIN CORROSIVITY AND PHOTOTOXICITY USING AN IN VITRO MODEL OF HUMAN EPIDERMIS.
Liebsch, M.
ZEBET, Berlin, Germany.
Presented at 3rd Annual Symposium International Business Conferences on "In Vitro Testing Methods for Cosmetics", Washington, DC, Nov. 16-17, (1998).
|
166. |
|
FURTHER EVALUATION OF THE EPIDERM AND EPIOCULAR IN VITRO IRRITATION MODELS.
Nicastro, S.C., Ladics, G.S.
The DuPont Co., Haskell Laboratory for ToxicoIogy and Industrial Medicine, Newark, DE.
SOT 1999 Annual Meeting. The Toxicologist, 48 (1-S), 70, Soc. of Toxicology (Reston, VA), Abstract #360, (1999).
|
165. |
|
TOPICALLY APPLIED LACTIC ACID INCREASES SPONTANEOUS SECRETION OF VASCULAR ENDOTHELIAL GROWTH FACTOR/VASCULAR PERMEABILITY FACTOR (VEGF/VPF) BY HUMAN RECONSTRUCTED EPIDERMIS.
Rendl*, M., Mayer*, C., Tschachler*1, E.
*DIAID, Department of Dermatology, University of Vienna Medical School, Vienna, Austria, 1C.E.R.I.E.S., Neuilly, France.
J. Invest. Dermatol., 112, 625, Abstract #614, (1999).
|
164. |
|
ULTRAVIOLET B RADIATION UPREGULATES THE PRODUCTION OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) IN HUMAN EPIDERMAL KERATINOCYTES.
Shimizu, T., Abe, R., Ohkawara,A., Nishihira*, J.
Department of Dermatology and *Central Research Institute, Hokkaido University School of Medicine, Sapporo, Japan.
J. Invest. Dermatol., 112:210-215, (1999).
|
163. |
|
MELANODERM™, AN EPIDERMAL MODEL CONTAINING FUNCTIONAL MELANOCYTES.
Klausner, M., Neal, P., Breyfogle, B., Kubilus, J.
MatTek Corp., Ashland, MA.
Presented at IBC 3rd Annual Conference on "Cosmeceuticals", Short Hills, NJ, February 4-5, (1999).
|
162. |
|
EVALUATION OF A NEW ALTERNATIVE TO PRIMARY DRAIZE SKIN IRRITATION TESTING USING THE EPIDERM SKIN MODEL.
Genno1, M., Yamamoto1, R., Kojima2, H., Konishi2, H., Klausner3, M.
1Technical Research Laboratory, Kurabo Industries Ltd. 14-5, Shimokida-cho1 Neyagawa-shi, Osaka, 572-0823, Japan, 2Research Institute, Nippon Menard Cosmetic Co., Ltd., 2-7, Torimi-cho, Nishiku, Nagoya, 451-0071, Japan, 3MatTek Corp., 200 Homer Avenue, Ashland, MA 01721 USA.
Altern. Animal Test. Experiment, 5, 195-200 (1998).
|
161. |
|
RECONSTITUTED 3-DIMENSIONAL HUMAN SKIN AS A NOVEL IN VITRO MODEL FOR STUDIES OF CARCINOGENESIS.
Zhao1, J.F., Thang2, Y.J., Kubilus3, J., Jin1, X.H., Santella2, R.M., Athar1, M., Wang1, Z.Y., Bickers1, D.R.
1Department of Dermatology and 2Division of Environmental Health Sciences, Columbia University, New York, NY 10032, 3MatTek Corp., Ashland, MA 01721.
Biochem Biophys Res Commun, 254, 49-53, (1999).
|
158. |
|
TISSUE ABLATION WITH 100-fs AND 200-ps LASER PULSES.
Nishimura, N., Schaffer, E., Li, E., Mazur, E.
Department of Physics, Harvard University, Cambridge, MA 02138.
Conference Proceedings of IEEE Engineering, Medicine & Biology. (In press) (1999).
|
157. |
|
IN VITRO SCREENING TECHNIQUES IN DERMATOLOGY.
Majmudar, G., Smith, M.
Mary Kay Holding Corp., Dallas, TX.
Cosmetics & Toiletries Magazine, 113, 69-72, (1998)
|
155. |
|
DEVELOPMENT OF A NEW IN VITRO TEST FOR DERMAL PHOTOTOXICITY USING A MODEL OF RECONSTITUTED HUMAN EPIDERMIS (EPIDERM).
Liebsch, M., Barrabas, C., Traue, D., Spielmann, H.
ZEBET, Berlin, Germany.
ALTEX, 14:165-174 (1997).
|
154. |
|
BIOCONVERSION OF TOCOPHERYL ACETATE TO TOCOPHEROL IN HUMAN SKIN ORGAN CULTURE MODELS.
Nabi, Z., Tavakkol, A., Soliman, N., Polefka, T.G.
Personal Care Products, Colgate-Palmolive Co., Piscataway, NJ, USA.
J. Invest. Dermatol., 110(4), 679, Abstr. #1239 (1998).
|
153. |
|
INITIAL RESULTS WITH EPI-201, A DEVELOPING IN VITRO MODEL OF HUMAN EPIDERMIS.
Klausner, M., Neal, P., Kubilus, J.
MatTek Corp., Ashland MA, USA.
J. Invest. Dermatol., 110(4), 558, Abstr. #513 (1998).
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152. |
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VISUALIZATION OF IONTOPHORETIC TRANSPORT PATHS IN CULTURED AND ANIMAL SKIN MODELS.
Lee*, R.D., White*, H.S., Scott†, E.R.
*Department of Chemistry, University of Utah, Salt Lake City, UT, †Alza Corporation 8295 Central Avenue NE, Spring Lake Park, MN
J. Pharmaceutical Sciences, 85 (11), 1186, American Chemical Society and American Pharmaceutical Association (1996).
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151. |
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MATTEK'S TISSUE MODELS: NEW DEVELOPMENTS.
Klausner, M.
MatTek Corp., Ashland, MA 01721.
Presented at International Business Conference, "Latest In Vitro Testing Methods for Skin Care, Cosmetics, and Household Products," Washington, D.C., (1997).
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150. |
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RECONSTITUTED 3-DIMENSIONAL HUMAN SKIN, A NEW IN VITRO MODEL FOR SKIN CARCINOGENESIS STUDY.
Zhao1, J.F., Zhan1, Y.J., Kubilus2, J., Jin1, X.H., Bickers1, D.R., Wang1, Z.Y.
1Department of Dermatology and Division of Environmental Science, Columbia University, New York, NY 10032, 2MatTek Corp., Ashland, MA 01721
J. Invest. Dermatol., 110(4), 525, Abstr. #319 (1998).
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149. |
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LOCALIZATION OF β-GLUCOCEREBROSIDASE ACTIVITY IN MAMMALIAN EPIDERMIS BY IN SITU ZYMOGRAPHY.
Kriehuber, E., Takagi, Y., Imokawa, G., Elias, P.M., Holleran, W.M.
Department of Dermatology, University of California, Dermatology Service, V.A. Medical Center, San Francisco, CA, Kao Corp., Tochigi, Japan.
J. Invest. Dermatol., 108(4), 594, Abstr. #337 (1997).
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148. |
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DEVELOPMENT OF AN IN VITRO METHOD FOR SKIN CORROSION TESTING.
Perkins, M.A., Osborne, R., Johnson, G.R.
The Procter & Gamble Co., Cincinnati, OH.
(1996). Fundam. Appl. Toxicol., 31, 9-18, (1996).
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145. |
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DEVELOPMENT OF AN IN VITRO MODEL FOR THE PREDICTION OF SKIN IRRITATION POTENTIAL.
Bernhofer, L.P., Seiberg, M., Martin, K.M.
Johnson & Johnson Consumer Products Worldwide, Skillman, NJ 08558.
Presented at 1997 Congress on In Vitro Biology, Washington, D.C. (1997).
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144. |
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COMPARISON OF AN IN VITRO HUMAN SKIN EQUIVALENT MODEL TO NORMAL HUMAN SKIN FOR DERMATOLOGICAL RESEARCH.
Monteiro-Riviere1, N.A., Inman1, A.O., Qiao1, G., Snider2, T.H., Blank2, J.A., Hobson3, D.W.
1North Carolina State University, Cutaneous Pharmacology and Toxicology Center, Raleigh, NC, 2Battelle Memorial Research Institute, Columbus, OH, 3Dermatological Products of Texas, San Antonio, TX, USA.
Perspectives in Percutaneous Penetration, 5a, 65, (1997), also published in Microsc. Res. Tech., 37, 3, 172-9, (1997).
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143. |
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PRESENCE OF HYDROCORTISONE DRAMATICALLY AFFECTS CYTOKINE PRODUCTION FOLLOWING UV IRRADIATION IN 3-DIMENSIONAL SKIN MODEL EPIDERM.
Sennott, H., Makwana, A., Kubilus, J., Klausner, M.
MatTek Corp., Ashland, MA.
J. Invest. Dermatol., 108(4), 665, Abstr. #765 (1997).
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140. |
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MODULATION OF CYTOKINE MESSAGE IN THE EPIDERM IN VITRO SKIN MODEL FOLLOWING TREATMENT WITH CONTACT ALLERGENS AND SKIN IRRITANTS.
Sikorski, E.E., Gerberick, G.F., Limardi, L.C.
The Procter & Gamble Company, Cincinnati, OH.
The Toxicologist, 36 (1), 192, Soc. of Toxicol. (Reston, VA), Abstract #977, (1997).
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138. |
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NEW DRUG DELIVERY SYSTEMS: VALIDATION OF IN VITRO MODELS.
Daddona, P.
ALZA Corporation, Palo Alto, CA.
ATLA, 24, Special Issue, 111, (1996).
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137. |
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SKIN IRRITATION POTENTIAL OF SURFACTANT MIXTURES: USING RELEVANT DOSES IN IN VITRO SYSTEMS.
Earl, L.K., Hall-Manning, T.J., Holland, G.H., Irwin, A., McPherson, J.P., Southee, J.A.
Unilever Research, Colworth House, Sharnbrrok, Bedford , UK, Microbiological Associates Ltd, Stirling University, Innovation Park, Stirling, UK.
ATLA, 24, Special Issue, 249, Abstract #73, (1996).
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136. |
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A REPRODUCIBLE, STRUCTURALLY APPROPRIATE SKIN MODEL FOR DERMAL IRRITANCY AND EFFICACY TESTING.
Klausner, M., Kubilus, J., Neal, P., Cannon, C.L., Sennott, H., Ogle, P.
MatTek Corp., Ashland, MA.
ATLA, 24, Special Issue, 263, Abstract #100, (1996).
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134. |
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COMPARISON OF IN VITRO AND IN VIVO HUMAN SKIN RESPONSES TO CONSUMER PRODUCTS AND INGREDIENTS WITH A RANGE OF IRRITANCY POTENTIAL.
Perkins, M. A., Osborne, R., Robinson, M. K., Rana,F., Ghassemi, A., Hall, B.
The Procter & Gamble Company, Corporate Professional & Regulatory Services Division, Cincinnati, OH.
The Toxicologist, 30 (1), 168, Soc. of Toxicol. (Reston, VA), Abstract #864, (1996).
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133. |
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CYTOKINE AND LIPID MEDIATOR RELEASE FROM IN VITRO SKIN MODELS FOLLOWING DETERGENT TREATMENT OR PHYSICAL WOUNDING.
Hayden, P.J.
Gillette Research Institute, Gaithersburg, MD.
J. Invest. Dermatol., 106(4), 936, Abstract #782 (1996).
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132. |
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CYTOKINE GENE EXPRESSION IN THE MATTEK EPIDERM™ CULTURES.
Limardi, L.C., Sikorski, E.E., Gerberick, G.F.
The Procter and Gamble Company, Cincinnati, Ohio.
J. Invest. Dermatol., 106(4), 939, Abstract #803 (1996).
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131. |
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INTRA- AND INTER-LOT VARIABILITY OF EPIDERM™, AN EPIDERMAL MODEL FOR DERMAL RESEARCH AND TESTING.
Ogle, P., Sennott, H., Neal, P.J., Cannon, C.L., Kubilus, J., Klausner, M.
MatTek Corp., Ashland, MA.
J. Invest. Dermatol., 106(4), 868, Abstract #377 (1996).
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128. |
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AN IN VITRO METHOD TO EVALUATE THE ANTIOXIDANT EFFICACY OF TOPICAL FORMULATIONS.
Appa, Y., Asuncion, A. G., Podda, M., Duke, M. A., Rachui, S.R.
Neutrogena Corporation, Los Angeles, CA., Department of Molecular & Cell Biology, University of California at Berkeley, Stephens & Associates, Inc., Dallas, TX.
Presented at American Acad. of Dermatol. Annual Meeting (1996).
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127. |
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THE USE OF MATTEK EPIDERMAL EQUIVALENTS FOR PREDICTION OF IRRITATION POTENTIAL.
Bernhofer, L., Juneja, C., Martin, K.
In Vitro Toxicology and Pharmacology Group., Johnson & Johnson Consumer Products Worldwide, Skillman, NJ
J. Invest. Dermatol., 105(6), 874, Abstract (1995).
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126. |
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A COMPARISON STUDY OF FOUR IN VITRO PHOTOTOXICITY SYSTEMS.
Rachui, S.R., Robertson, W.D., Duke, M.A., Allen, R.
Stephens & Associates, Inc., Shaklee Corporation
Presented at The CTFA 52nd Scientific Conference, Orlando, FL. November (1995).
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125. |
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DEVELOPMENT OF IN VITRO METHODS FOR EVALUATING THE EPIDERMAL AND DERMAL EFFECTS OF ALPHA HYDROXY AND AMIDES.
Wolf*, B.A., Kwan, S.C., Moral, J.A., Rhein, L.
*Almay Advanced Skin Care Institute, Revlon International Skin Study Center, Edison, NJ.,
J. Invest. Dermatol., 104(4), 639, Abstract #511 (1995).
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124. |
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IN VITRO PERMEATION AND IRRITATION OF BENZOYL PEROXIDE - CONTAINING PRODUCTS.
Fares*, H.M., Chatterjee, S., Hayward, M.
SmithKline Beecham Consumer Healthcare, 1500 Littleton Road, Parsippany, NJ 07054.
Presented at American Association of Pharmaceutical Scientists 10th Annual Meeting, Paper No. PDD 7352, November, (1995).
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123. |
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PREDICTIVE TESTING: UNDERSTANDING THE ROLE OF IN VITRO AND IN VIVO TESTING.
Harbell, J.W., Mun, G.C., Wallace, K., Kreuzmann, J., Wild, J., Mills, O., Berger, R.
Microbiological Assoc., Hill Top Research, Inc., Univ. of Medicine & Dentistry of NJ.
Presented at the 24th Annual Meeting of the American College of Clinical Pharmacology. J. Clinical Pharmacology, 35(9), 931, (1995).
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122. |
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INITIAL CHARACTERIZATION OF AN EPIDERMAL MODEL CONTAINING FUNCTIONAL MELANOCYTES.
Klausner, M., Kubilus, J., Neal, P.J.
MatTek Corp., Ashland, MA.
J. Invest. Dermatology, 104(4), 616, Abstr. # 370 (1995).
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121. |
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CYTOKINE RESPONSE OF THE EPIDERM SKIN MODEL TO TOPICALLY APPLIED IRRITANTS AND TOXICANTS.
Kubilus, J., Cannon, C.L., Neal, P.J., Ricker, H.A., Klausner, M.
MatTek Corp., Ashland, MA.
In Vitro Toxicol., 9(2), 157 (1996).
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120. |
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A COMPARISON OF THREE DIMENSIONAL HUMAN SKIN MODELS TO EVALUATE THE DERMAL IRRITATION OF SELECTED PETROLEUM PRODUCTS.
F.J. Koschier1, R.N. Roth1, K.A. Wallace1, R.D. Curren2, J.W. Harbell2.
1ARCO, Los Angeles, CA, 2Microbiological Assoc., Inc., Rockville, MD.
Presented at CAAT Symposium: "In Vitro Approaches to Contact Dermatitis", Baltimore, MD, March (1995).
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119. |
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UVB IRRADIATION OF AN ORGANOTYPIC SKIN MODEL, EPIDERM™, RESULTS IN SIGNIFICANT RELEASE OF CYTOKINES.
Klausner, M., Kubilus, J., Ricker, H.A., Neal, P. J.
MatTek Corp.
The Toxicologist, 15(1)., Soc. of Toxicology, Reston VA. Abstract #1745 (1995).
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118. |
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DEVELOPMENT OF HISTOPATHOLOGIC CRITERIA FOR ASSESSING IN VITRO SKIN CORROSION.
Perkins, M.A., Osborne, R., Johnson, G.R.
Procter & Gamble Company.
The Toxicologist, 15(1)., Soc. of Toxicology, Reston VA. Abstract #650 (1995).
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117. |
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EFFECT OF LAUNDERING ON ABILITY OF GLOVE FABRICS TO DECREASE THE PENETRATION OF ORGANOPHOSPHATE INSECTICIDES THROUGH IN VITRO EPIDERMAL SYSTEMS.
Keeble, V.B., Correll, L., Ehrich, M.
Department of Clothing and Textiles, College of Human Resources (Virginia Tech University), Blacksburg, VA, USA.
J Appl Toxicol, 16, (5), 401-6, (1996).
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116. |
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USE OF THE MATTEK EPI-100 IN VITRO SYSTEM TO SCREEN ANTIOXIDANT EFFICACY.
Rachui, S.R., Duke, M.A., Allen, R.
Thomas Stephens & Associates, Inc.
J. Toxicol. - Cutan. Ocul. Toxicol., 14(4), 237-250 (1995).
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114. |
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EVALUATION OF TWO IN VITRO HUMAN SKIN EQUIVALENTS (THE EPIDERM™ AND SKIN²™ MODEL ZK1300) FOR ASSESSING THE SKIN IRRITATION POTENTIAL OF PERSONAL CARE PRODUCTS AND CHEMICALS.
Doyle1, J.M., Dressler1, W., Rachui2, S.R.
1Clairol, Inc., Stamford, CT, USA, 2Thomas Stephens Associates, Carrollton, TX USA.
Presented at symposium, "Alternatives in the Assessment of Toxicity; Theory & Practice," Aberdeen, MD, May (1994).
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113. |
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INTRA- AND INTERLABORATORY REPRODUCIBILITY (ET-50) OF EPIDERM, AN IN VITRO MODEL FOR DERMAL IRRITANCY TESTING.
Cannon1, C.L., Neal1, P.J., Kubilus1, J., Klausner1, M., Harbell2, J.W., Curren2, R.D.
1MatTek Corp., 200 Homer Ave., Ashland, MA 01721, 2Microbiological Assoc., 9900 Blackwell Avenue, Rockville, MD 20850.
Presented at symposium, "Alternatives in the Assessment of Toxicity; Theory & Practice," Aberdeen, MD, May (1994).
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112. |
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LIPID AND ULTRASTRUCTURAL CHARACTERIZATION OF A NEW EPIDERMAL MODEL SHOWS GOOD CORRESPONDENCE TO NORMAL HUMAN EPIDERMIS.
Cannon1, C.L., Neal1, P.J., Kubilus1, J., Klausner1, M., Swartendruber2, D.C., Squier2, C.A., Kremer2, M.J., Wertz2, P.W.
1MatTek Corp., Ashland, MA 01721, 2University of Iowa, College of Dentistry, Iowa City, IA 54224 USA.
J. of Invest. Dermatol., 102(4), 641 Abstract #458, (1994).
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111. |
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ALAMAR BLUE DISCLOSES LATENT TOXICITY OF VESICANT IN HUMAN EPIDERMAL MODEL AND CELLS.
Rhoads1, L.S., Mershon1, M.M., Van Buskirk2, R.G.,
1United States Army Medical Research Institute of Chemical Defense, Drug Assessment Division, Aberdeen Proving Ground, MD; 2Dept. of Biological Sciences, State University of New York, Binghamton, NY.
J. of Toxicology - Cut. & Ocular Toxicol., 13(4), 289 (1994).
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110. |
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A SYNTHETIC HUMAN EPIDERMAL MODEL CAN DIFFERENTIATE ACUTE FROM LATENT EFFECTS OF THE MONOFUNCTIONAL MUSTARD ANALOGUE, 2-CHLOROETHYLETHYL SULFIDE.
Rhoads1, L.S., Mershon1, M.M., Van Buskirk2, R.G., Eichelberger2, H., Cook2, J.R.
1United States Army Medical Research Institute of Chemical Defense, Drug Assessment Division, Aberdeen Proving Ground, MD; 2Dept. of Biological Sciences, State University of New York, Binghamton, NY.
In Vitro Toxicology, 7(2), 69 (1994).
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109. |
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APPLICATION OF AN IN VITRO METHOD FOR SKIN CORROSION TESTING TO A VARIETY OF COMMERCIALLY AVAILABLE SKIN CULTURES.
Perkins, M.A., Osborne, R.
Corporate Professional Human Safety Department, Procter & Gamble Co., Miami Valley Labs, Cincinnati, OH 45239-8707 USA.
J. of Invest. Dermatol., 102 (4), 641 Abstract #707, (1994).
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108. |
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COMPARISONS OF IN VITRO AND IN VIVO SKIN RESPONSES TO SURFACTANTS WITH A RANGE OF IRRITANCY POTENTIAL.
Hall1, B., Osborne2, R., Perkins2, M.A.
The Procter & Gamble Company, Human Safety Department, Cincinnati, Ohio2 45239-8707, Egham Surrey, U.K.1
Presented at "International Symposium on Irritant Contact Dermatitis," Zurich, Switzerland, Poster #44P, April (1994).
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107. |
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INTER-AND INTRALABORATORY REPRODUCIBILITY OF A THREE DIMENSIONAL HUMAN EPIDERMAL MODEL - EPIDERM.
Harbell1, J.W., Southee1, J.A., Cannon2, C.L., Neal2, P.J., Kubilus2, J., Klausner2, M.
1Microbiological Assoc., Int., Ltd., Stirling University Innovation Park Stirling, FK94NF, Scotland, 2MatTek Corp., 200 Homer Ave., Ashland, MA 01721 USA, R.D.Curren (Sponsor).
The Toxicologist, 14(1), Society of Toxicology (Reston, VA), Abstract #350. Presented at Annual Meeting, Dallas, TX, March (1994).
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106. |
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LOT-TO-LOT VARIABILITY OF EPIDERM, AN EPIDERMAL MODEL FOR DERMAL IRRITANCY TESTING.
Cannon, C.L., Neal, P.J., Kubilus, J., Klausner, M.
MatTek Corp., 200 Homer Ave., Ashland, MA 01721, USA.
The Toxicologist, 14(1), Society of Toxicology (Reston, VA), Abstract #349. Presented at Annual Meeting, Dallas, TX, March (1994).
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105. |
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USE OF AN IN VITRO SKIN MODEL TO PREDICT CHEMICAL CORROSIVITY.
Lake1, L.K., Swanson1, J.E., Kubilus2, J., Neal2, P.J., Klausner2, M.
1S.C. Johnson & Son, Inc., Racine WI, 2MatTek Corp., 200 Homer Ave., Ashland, MA 01721 USA.
The Toxicologist, 14(1), Society of Toxicology (Reston, VA), Abstract #340. Presented at Annual Meeting, Dallas, TX, March (1994).
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104. |
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LIPID CHARACTERIZATION OF A NEW EPIDERMAL MODEL FOR SKIN IRRITANCY AND PENETRATION STUDIES.
Cannon1, C.L., Neal1, P.J., Kubilus1, J, Klausner1, M., Swartendruber2, D.C., Squier2, C.A., Wertz2, P.W.
1MatTek Corp., Ashland, MA 01721, 2University of Iowa, College of Dentistry, Iowa City, IA 54224 USA.
Presented at "World Congress on Alternatives and Animal Use in the Life Sciences," Baltimore, MD, November (1993).
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103. |
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NEW EPIDERMAL MODEL FOR DERMAL IRRITANCY TESTING.
Cannon2, C.L., Neal2, P.J., Southee1, J.A., Kubilus2, J., Klausner2, M.
1Microbiological Associates International, Ltd., Stirling University Innovation Park, Stirling, FK9 4NF, Scotland, 2MatTek Corp., 200 Homer Ave., Ashland, MA 01721 USA.
Presented at symposium, "Practical In Vitro Toxicology III," Nottingham, U.K. July (1993). Toxic. In Vitro, 8(4), 889-891, (1994).
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102. |
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INITIAL CHARACTERIZATION OF A NEW MODEL FOR DERMAL IRRITANCY TESTING.
Cannon, C.L., Neal, P.J., Kubilus, J., Klausner, M.
MatTek Corp., 200 Homer Ave., Ashland, MA 01721, USA.
Presented at Tissue Culture Association annual meeting, San Diego, CA, June (1993).
|
101. |
|
NEW EPIDERMAL MODEL FOR DERMAL IRRITANCY TESTING.
Cannon, C.L., Neal, P.J., Kubilus, J., Klausner, M.
MatTek Corp., 200 Homer Ave., Ashland, MA 01721 USA.
Presented at J.F. Morgan Research Foundation symposium, "Current Trends in In Vitro Skin Toxicology and Eye Irritancy Testing," Ottawa, Canada, April (1993).
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100. |
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ABSTRACT PAK
In order to facilitate the literature review process, the Abstract Pak contains the abstract portions of the listed posters and publications.
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