EpiDermTM Technical References
468. |
NEW! |
IDENTIFICATION AND CHARACTERIZATION OF ALLERGENS: IN VITRO APPROACHES.
Basketter, D. and Maxwell, G.
Unilever, Safety and Environmental Assurance Centre, Sharnbrook, Bedford, UK.
Expert Rev. Dermatol. 2(4), 472-479 (2007).
|
466. |
NEW! |
AN IN VITRO MODEL SYSTEM TO STUDY THE DAMAGING EFFECTS OF PROLONGED MECHANICAL LOADING OF THE EPIDERMIS.
Bronneberg, D., Bouten, C.V.C., Oomens, C.W.J., Van Kemenade, P.M. and Baaijens, F.P.T.
Department of Biomedical Engineering, Eindhoven University of Technology, P.O. Box 513, 5600 MB, Eindhoven, The Netherlands.
Annals of Biomed. Engineering, 34, 3, 506-514, (2006).
|
465. |
NEW! |
SUNSCREEN ENHANCEMENT OF UV-INDUCED REACTIVE OXYGEN SPECIES IN THE SKIN.
Hanson1, K.M., Gratton2, E., Bardeen1, C.J.
1Department of Chemistry, University of California at Riverside, Riverside, CA 92506, USA. 2Laboratory for Fluorescence Dynamics, Department of Bioengineering, University of California at Irvine, Irvine, CA 92697, USA.
Free Radical Bio. & Medicine, 41, 1205-1212, (2006).
|
464. |
NEW! |
COMPARISON OF HUMAN PATCH TEST AND 3D HUMAN SKIN MODEL RESULTS WITH CLASSIFICATION OF CHEMICALS BASED ON RABBIT DRAIZE TEST.
Bendova1, H., Basketter2, D., Kandarova3, H., Marriott4, M., Kejjlova1,K., Jirova1, D., Spiller3, E., Maly1, M., and Liebsch5, M.
1National Institute of Public Health, CZ – Prague, 2St. John’s Institute of Dermatology, St. Thomas’ Hospital, London, UK, 3MatTek Corporation, Ashland, MA, USA, 4Safety and Environmental Assurance Center, Unilever Colworth Laboratory, UK – Bedford, 5ZEBET, Federal Institute for Risk Assessment, D – Berlin.
11th Annual Meeting of MEGAT, Univ. of Linz, Austria, September (2007).
|
463. |
NEW! |
CHARACTERIZATION OF THE EFFECT OF URINE ON MECHANICALLY INDUCED SKIN DAMAGE.
Sonsma1, J.,
Grin1, P.C., Jorritsma1, P.A., Bronneberg2, D., Bouten2, C.V.C., Oomens2, C.W.J., and Baaijens2, F.P.T.
1VHall Instituut Leeuwarden, Unit Life Sciences, Biotechnology. 2Eindhoven University of Technology, Department of Biomedical Engineering, Section Soft Tissue Biomechanics and Engineering.
BMTE, 06.28, (2006).
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462. |
NEW! |
CYTOKINE AND CHEMOKINE RELEASE UPON PROLONGED MECHANICAL LOADING OF THE EPIDERMIS.
Bronneberg1, D., Spiekstra2, S.W., Cornelissen1, L.H., Oomens1, C.W.J., Gibbs2, S., Baaijens1, F.P.T. and Bouten1, C.V.C.
1Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands. 2Department of Dermatology, VU University Medical Center, Amsterdam, The Netherlands.
Dermatology, 16, 567-573, (2007).
|
461. |
NEW! |
IN VITRO SKIN CORROSION TEST: LONG TERM REPRODUCIBILITY AND RELIABILITY FOR A REGULATORY ACCEPTED METHOD.
Chua1, G., Kandarova1, H., Raabe2, H., Klausner1, M., Kubilus1, J., Hayden1, P., Ayehunie1, S., Kaluzhny1, Y., Curren2, R., Sheasgreen1, J.
1MatTek Corporation, Ashland, MA; 2Institute for In Vitro Sciences, Inc. Gaithersburg, MD.
Presented at 6th World Congress on Alternatives and Animal Use, Tokyo, August (2007).
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459. |
NEW! |
IN VITRO SKIN IRRITATION TEST: INCREASING THE SENSITIVITY OF THE EPIDERM SKIN IRRITATION PROTOCOL EVALUATED IN THE ECVAM SKIN IRRITATION VALIDATION STUDY.
Kandárová1, H., Torishima2, H., Hayden1, P., Spiller1, E., Klausner1, M., Kubilus1, J., and Sheasgreen1, J.
1MatTek Corporation, Ashland, MA; 2Kurabo Industries, Ltd., Osaka, Japan.
Presented at 6th World Congress on Alternatives and Animal Use, Tokyo, August (2007). Presented at 44th Congress of the European Societies of Toxicology, Amsterdam, The Netherlands, 2007.
|
458. |
NEW! |
GENOTOXICITY TESTING USING THE MICRONULCEUS ASSAY IN THE EPIDERM™ HUMAN 3D SKIN MODEL.
Kaluzhny1, Y., Curren2, R., Aardema3, M., Hu3, T., Klausner1, M., Karetsky1, V., Hayden1, P., Kandarova1, H., Sheasgreen1, J.
1MatTek Corporation, Ashland, MA, USA; 2Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA; 3The Procter & Gamble Co., Cincinnati, OH, USA.
Presented at the 6th World Congress on Alternatives and Animal Use in the Life Sciences, Tokyo, Japan August 21-25, (2007).
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452. |
NEW! |
INHIBITION OF TUMOUR NECROSIS FACTOR-Α SECRETION FROM EPIDERM™ TISSUES BY A NOVEL SMALL MOLECULE, UTL-5D.
Shaw1, J., Liu1, C., Martin1, R., Chen2, B., Holtz3, R., Huanq4, W.H, Lee4, A.R.
1Unitech Pharmaceuticals, Inc., 4370 Varsity Drive, Ann Arbor, MI 48108, USA, 2Department of Internal Medicine, Wayne State University, Detroit, MI, USA, 3BioInnovation Laboratories, Inc., Lakewood, CO, USA, 4School of Pharmacy, National Defense Medical Center, Taipei, Taiwan.
Br. J. of Dermatology, 157, 575-579, (2007).
|
444. |
NEW! |
AN IN VITRO SYSTEM FOR PREDICTING SKIN IRRITATION OF LIQUID ANTIPERSPIRANTS.
McPhail, S., Lanzalaco, A.C., Kolodzik, J., Osborne, R.
Procter & Gamble Company, Mason, OH 45040.
68th Annual Meeting of the Society for Investigative Dermatology, Los Angeles, CA, (2007).
|
443. |
NEW! |
USE OF THE COMET ASSAY TO DETECT GENOTOXIC EFFECTS IN RECONSTITUTED HUMAN SKIN.
Zeller, A., Richoz, L., Corbino, L. and Pfuhler, S.
Experimental Product Safety, The Procter & Gamble Co., Wella-Cosmital SA, Marly, Switzerland.
Society of Toxicology 46th Annual Meeting, Charlotte, NC, (2007). Abstract #1171.
|
442. |
NEW! |
REGULATORY REQUIREMENTS FOR IN VITRO SYSTEMS TO MEET PERFORMANCE STANDARDS OVER TIME AS WELL AS DURING VALIDATION.
Klausner, M., Kubilus, J., Ayehunie, S., Hayden, P., Chua, G., Sheasgreen, J.
MatTek Corporation, Ashland, MA 01721.
Society of Toxicology 46th Annual Meeting, Charlotte, NC, Abstract 1524, (2007).
|
441. |
NEW! |
COMPARISON OF IN VITRO PHOTOTOXICITY TEST METHODS: 3T3 NRU PT VS. ENHANCED PHOTOTOXICITY SCREENING ASSAY IN RECONSTITUTED SKIN (EPARS).
Pratt, L., Kirk, C., Reeder, M., DeGeorge, G.
MB Research Laboratories, Spinnerstown, PA.
Society of Toxicology 46th Annual Meeting, Charlotte, NC, (2007)., Poster 441.
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437. |
NEW! |
INJURY ENHANCES TLR2 FUNCTION AND ANTIMICROBIAL PEPTIDE EXPRESSION THROUGH A VITAMIN D–DEPENDENT MECHANISM.
Schauber1, J., Dorschner1, R.A., Coda1, A.B., Büchau1, A.S., Liu2, P.T., Kiken1, D., Helfrich3, J.R., Kang3, S., Elalieh4, H.Z., Steinmeyer5, A., Zügel6, U., Bikle4, D.D., Modlin2, R.L. and Gallo1, R.L.
1Division of Dermatology, University of California, San Diego, and VA San Diego Healthcare System, San Diego, California, USA; 2Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA; 3Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA; 4Department of Medicine, Endocrine Unit, Veterans Affairs Medical Center, University of California, San Francisco, San Francisco, California, USA; 5Medicinal Chemistry and 6Corporate Research Business Area Inflammation, Schering AG, Berlin, Germany.
J. Clinical Invest., 117, (3), 803-811, (2007).
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435. |
NEW! |
COMPARISON OF CORROSITEX AND EPIDERM IN VITRO SKIN CORROSION SCREENING ASSAYS TO IN VIVO CORROSIVITY RESULTS.
Wilson, D.M., McMullin, T.T. Kan, H.L., Golden, R.M. Stott, W.T.
Dow Chemical, Midland, MI, USA.
Society of Toxicology 46th Annual Meeting, Charlotte, NC, (2007).
|
434. |
NEW! |
IN VITRO AND IN VIVO COMPARISON OF DERMAL IRRITANCY OF JET FUEL EXPOSURE USING EPIDERM (EPI-200) CULTURED HUMAN SKIN AND HAIRLESS RATS.
Chatterjee1, A., Babu2, R.J., Klausner3, M., Singh1, M.
1College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL 32307, United States; 2Department of Pharmacal Sciences, Harrison School of Pharmacy, Auburn University, AL 36849, United States; 3MatTek Corporation, 200 Homer Avenue, Ashland, MA 01721, United States.
Toxicology Letters, 167, 85-94, (2006).
|
433. |
NEW! |
INJURY-INDUCED INNATE IMMUNE RESPONSE IN HUMAN SKIN MEDIATED BY TRANSACTIVATION OF THE EPIDERMAL GROWTH FACTOR RECEPTOR.
Sorensen1, O.E., Thapa2, D.R., Roupe1, K.M., Valore2, E.V., Sjobring1, U., Roberts2, A.A., Schmidtchen3, A., and Ganz2, T.
1Section of Clinical and Experimental Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden. 2Host Defense Research Laboratory, Department of Medicine and Pathology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA. 3Department of Dermatology and Venereology, Lund University, Lund, Sweden.
J. Clinical Invest., 116, (7), 1878-1885, (2006).
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432. |
NEW! |
THE EFFECTS OF IL-20 SUBFAMILY CYTOKINES ON RECONSTITUTED HUMAN EPIDERMIS SUGGEST POTENTIAL ROLES IN CUTANEOUS INNATE DEFENSE AND PATHOGENIC ADAPTIVE IMMUNITY IN PSORIASIS.
1Sa, S.M., Valdez, P.A., Wu, J., Jung, K., Zhong, F., Hall, L., Kasman, I., Winer, J., Modrusan, Z., Danilenko, D.M., Ouyang, W.
1Genentech, Department of Pathology, South San Francisco, CA.
Immunology, 2229-2240 (2007).
|
427. |
NEW! |
FURTHER DEVELOPMENT OF A MICRONUCLEUS ASSAY USING THE HUMAN 3-D SKIN MODEL, EPIDERM™.
Curren1, R.D., Aardema², M.J., Hayden³, P.J., Mun1, G., Hu², T.
1Institute for In Vitro Sciences, Gaithersburg, MD, ²Procter & Gamble, Cincinnati, OH, ³MatTek Corporation, Ashland, MA.
Presented at the 14th International Workshop on In Vitro Toxicology, Ostend, Belgium, October 2-5, (2006).
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423. |
NEW! |
THE COLIPA STRATEGY FOR THE DEVELOPMENT OF IN VITRO ALTERNATIVES: GENOTOXICITY.
Pfuhler1, S., Meunier2, J-R., Aardema3, M., Banduhn4, N., Fautz5, R., Manou6, I., Wolfreys7, A.
1Wella AG, Darmstadt, Germany, 2L’Oreal, Paris, France, 3Procter & Gamble, Cincinnati, OH, 4Henkel, Düsseldorf, Germany, 5Kao Professional Salon Services, Darmstadt, Germany, 6COLIPA, Brussels, Belgium, 7Unilever, Bedford, England.
Presented at the 5th World Congress, Berlin, Germany, August 21-25, (2005).
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419. |
NEW! |
GENE EXPRESSION PROFILING OF SKIN CARCINOGENSIS IN MICE.
Ridd1, K., Davies1, R., Judah1, D., Riley1, J., Zhang1, S.D, Wolfreys2, A., Greaves1, P., Gant1, T., Smith1, A.
1MRC Toxicology Unit, University of Leicester, Leicester, UK, 2Safety Environmental Assurance Centre, Unilever, Colworth, Bedford, UK.
Presented at the 6th Long-Range Research Initiative (LRI) Member Workshop, Brussels, Belgium, November 17-18, (2004).
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417. |
NEW! |
DESIGN PRINCIPLES OF CHEMICAL PENETRATION ENHANCERS FOR TRANSDERMAL DRUG DELIVERY.
Karande, P., Jain, A., Ergun, K., Kispersky, V., Mitragotri, S.
Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, CA 93106.
PNAS, 102, 13, 4688-4693 (2005)
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416. |
NEW! |
TGF-α REGULATES TLR EXPRESSION AND FUNCTION ON EPIDERMAL KERATINOCYTES.
Miller1, L.S., Sorensen1, O.E., Liu1, P.T., Jalian1, H.R., Eshtiaghpour1, D., Behmanesh1, B.E., Chung1, W., Starner2, T.D., Kim1, J., Sieling1, P.A., Ganz1, T., Modlin1, R.L.
1David Geffen School of Medicine, University of California, Los Angeles, California, 2Department of Pediatrics, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
The Journal of Immunology, 174, 6137-6143, (2005).
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412. |
NEW! |
IN VITRO SCREEN FOR PHOTOTOXICITY OPTIMIZED DRUG DEVELOPMENT USING A HIGHLY DIFFERENTIATED SKIN MODEL.
Klausner, M., Neal, P., Kubilus, J.
MatTek Corporation, Ashland, MA.
Presented at the AAPS 2006 Biotechnology Conference, Boston, MA., June (2006).
|
405. |
NEW! |
XENOBIOTIC METABOLIZING CAPABILITIES OF THE EPIDERM IN VITRO HUMAN SKIN EQUIVALENT.
Bolmarcich¹, J., Hayden¹, P. J., Stolper¹, G., Hu³, T., Aardema³, M., Curren², R., Klausner¹, M.
¹MatTek Corp., Ashland, MA, USA. ²Institute for In Vitro Sciences, Gaithersburg, MD, USA. ³Procter and Gamble Co., Cincinnati, OH, USA.
Presented at the Society of Investigative Dermatology Annual Meeting, Philadelphia, PA, May 3-6 (2006).
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403. |
NEW! |
EFFECTS IN UNIRRADIATED HUMAN TISSUE INDUCED BY RADIATION DAMAGE UP TO 1 MM AWAY.
Belyakov1,2, O.V., Mitchell1, S.A., Parikh3, D., Randers-Pehrson1, G., Marino1, S.A., Amundson1, S.A., Geard1, C.R. and Brenner1, D.J.
1Center for Radiological Research, Columbia University, New York, NY 10032; 2Radiation Biology Laboratory, Research and Environmental Surveillance, Radiation and Nuclear Safety Authority, P.O. Box 14, FIN-00881, Helsinki, Finland; and 3Stuyvesant High School, New York, NY 10282.
Proceedings of the Natl. Acad.of Sci. of the U.S.A, 102, 40, 14203-14208, October (2005).
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401. |
NEW! |
EVALUATION OF EPIDERM™ AS A MODEL TO STUDY IRRITATION AFTER EXPOSURE TO VARIOUS ALIPHATIC HYDROCARBONS FOUND IN JET FUELS.
Singh1, M., Babu2, R.J., Chatterjee1, A., Fulzele1, S.V., Klausner3, M., Kubilus3, J.
1College of Pharmacy, Florida A&M University, Tallahassee FL; 2Harrison School of Pharmacy, Auburn University AL; 3MatTek Corporation, 200 Homer Avenue, Ashland MA.
Presented at the 45th Society of Toxicology Meeting, San Diego, CA, March 5-9, (2006).
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397. |
NEW! |
PROTEOMIC ANALYSIS OF THE RESPONSE OF EPIDERM™ CULTURES TO SODIUM LAURYL SULPHATE.
Fletcher, S.T., Basketter, D.A.
Safety and Environmental Assurance Centre (SEAC), Unilever Colworth, Sharnbrook, Bedfordshire, UK.
Toxicology In Vitro, 20, (6), 975-985, (2006).
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392. |
NEW! |
USE OF HUMAN SKIN EQUIVALENT CULTURES FOR COSMETIC BENEFIT SCREENING.
McPhail1, S., Messersmith1, E., Thomas1, R., Mullins1, L., Osborne1, R., Grove2, G.
1Procter and Gamble, Miami Valley Innovation Center, Beauty Technology Division, 11810 East Miami River Road Cincinnati, OH 45252. 2CyberDERM, 700 Parkway, Broomall, PA 19008.
Presented at the American Academy of Dermatology, New Orleans, LA, February 19, (2005).
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387. |
NEW! |
PROTECTING THE SKIN AGAINST OZONE.
Gruber1, J.V., Tay1, A., Holtz2, R.
1Arch Personal Care Products, South Plainfield, NJ; 2Bioinnovation Laboratories, Inc., McKinney, TX.
Journal of Cosmetic Sciences, 56, (5), 348-349, (2005).
|
385. |
NEW! |
USE OF EPIDERM FULL THICKNESS TISSUE FOR ANTI-AGING STUDIES.
Gruber, V., et al.
Arch Personal Care Products L.P., South Plainfield, NJ and Bio-Innovation Laboratories, McKinney, TX.
|
381. |
NEW! |
VALIDATION OF HUMAN SKIN MODELS FOR SKIN CORROSIVITY TESTS IN JAPAN.
Ohno1, Y., Ando2, T., Inagaki3, K., Ohhira4, M., Kosaka5, T., Kojima6, H., Nakamura7, Y., Torishima8, H., Morikawa9, N., Omori10, T., Kanno2, J., Kuboki4, M., Genno8, M., Nokata3, M., Harada5, T.,Morimoto7, T., Yoshimura11, I.
1Div. Pharmacology, NIHS, 2Div. Toxicol. NIHS, 3Research Division, Nihon Nohyaku Co., Ltd., 4Toxicological Research Department, ODAWARA Research Center, Nippon Soda Co., Ltd., 5Toxicol. Div. The Inst. Environmental Toxicol., 6Res. Lab., Nippon Menard Cosmetic Co., Ltd., 7Environmental Health Science Lab., Sumitomo Chemical Co., Ltd., 8Bio-Medical Department, Kurabo Industries Ltd. 9Div. R&D, Gunze Ltd., 10Fac. Med. Kyoto Univ., 11Fac. Eng. Tokyo Univ. Science.
Presented at 5th World Congress, Berlin, Germany, August, (2005).
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380. |
NEW! |
CHARACTERIZATION OF THE EPIDERM™ HUMAN 3-D SKIN MODEL FOR GENOTOXICITY TESTING.
Aardema1, M., Curren2, R., Hayden3, P., Mun2, G., Gibson1, D., Hu1, T.
1The Procter & Gamble Co., Cincinnati, OH, USA; 2Institute for In Vitro Sciences, Gaithersburg, MD, USA; 3MatTek Corp., Ashland MA, USA.
Presented at 5th World Congress, Berlin, Germany, August, (2005).
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378. |
NEW! |
RECONSTRUCTED HUMAN EPIDERMIS FOR SKIN ABSORPTION TESTING: RESULTS OF THE GERMAN PREVALIDATION STUDY.
Schafer-Korting1, M., Bock2, U., Gamer3, A., Haberland1, A., Haltner-Ukaomadu2, E., Kaca2, M., Kamp3, H., Kietzmann4, M., Korting5, H.C., Krachter6, H-U., Lehr7, C.M., Liebsch8, M., Mehling6, A., Netzlaff7, F., Niedorf4, F., Rubbelke5, M.K., Schafer7, U., Schmidt8, E., Schreiber1, S., Schroder9, K-R., Spielmann8, H., Vuia1, A.
1Freie Universität Berlin, Institut für Pharmazie, Berlin, Germany, 2Across Barriers GmbH, Saarbrücken, Germany, 3BASF Aktiengesellschaft, Experimental Toxicology and Ecology, Ludwigshafen, Germany, 4Stiftung Tierärztliche Hochschule Hannover, Institut für Pharmakologie, Hannover, Germany, 5Ludwig-Maximilians-Universität München, Klinik und Poliklinik für Dermatologie und Allergologie, München, Germany, 6Cognis Deutschland GmbH & Co. KG, Düsseldorf, Germany, 7Universität des Saarlandes, Biopharmazie u. Pharmazeutische Technologie, Saarbrücken, Germany, 8ZEBET, Berlin, Germany, 9Henkel KGaA, Düsseldorf, Germany.
ATLA, 34, 283-294 (2006).
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377. |
NEW! |
PROGRAM TO REDUCE ANIMAL TESTING FOR EPA REGISTRATIONS OF ANTIMICROBIAL PRODUCTS.
Sauers1, L., Acuff1, K., Marsman1, D., Vedula2, U., Cuellar2, N., Curren3, R., Harbell3, J., Quinn4, P.
1The Proctor & Gamble Co., Cincinnati, Ohio, USA; 2S.C. Johnson, Racine, Wisconsin, USA; 3Institute for In Vitro Sciences, Gaithersburg, Maryland, USA; 4The Accord Group, Washington, DC, USA.
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372. |
|
ECVAM FEASIBILITY STUDY: CAN THE PRE-VALIDATED IN VITRO SKIN MODEL PHOTOTOXICITY ASSAY BE UPGRADED TO QUANTIFY PHOTOTOXIC POTENCY OF TOPICAL PHOTOTOXINS?
Kandárová1, H., Kejlová2, K., Jírová2, D., Bendová2, H., Tharmann1, J., Traue1, D., Spielmann1, H., Liebsch1, M.
1ZEBET at the BfR (Federal Institute for Risk Assessment), Berlin, Germany; 2National Institute of Public Health (SZU), Prague, Czech Republic.
Presented at 5th World Congress, Berlin, Germany, August 21-25, (2005).
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371. |
|
IN VITRO SKIN EQUIVALENT MODELS FOR TOXICITY TESTING.
Hayden, P.J., Ayehunie, S., Jackson, G.R., Kupfer-Lamore, S., Last, T.J., Klausner, M., Kubilus, J.
MatTek Corporation, Ashland, MA, U.S.A.
Published in Alternative Toxicological Methods. Editors H. Salem, S.A. Katz. CRC Press LLC, Boca Raton, FL, USA, 229-247 (2003).
|
369. |
|
BIOCONVERSION OF NALTREXONE AND ITS 3-O-ALKYL-ESTER PRODRUGS IN A HUMAN SKIN EQUIVALENT.
Hammell1, D.C., Stolarczyk1, E.I., Klausner2, M., Hamad1, M.O., Crooks1, P.A., Stinchcomb1, A.L.
1Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536-0082; 2MatTek Corporation, Ashland, Massachusetts 01721.
J Pharm Sci, 94, 828–836, (2005).
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367. |
|
DIFFERENTIAL REGULATION OF β-DEFENSIN EXPRESSION IN HUMAN SKIN BY MICROBIAL STIMULI.
Sørensen, O.E., Thapa, D.R., Rosenthal, A., Liu, L., Roberts, A.A., Ganz, T.
Department of Clinical Sciences, Biomedical Center B14, Lund University, Lund, Sweden.
J Immunology, 174, 4870–4879, (2005).
|
366. |
|
ANALYSIS OF GLOBAL GENE EXPRESSION PROFILE CHANGES DURING THE DIFFERENTIATION OF THE EPIDERM™ IN VITRO HUMAN SKIN EQUIVALENT.
Street1, T.L., Hayden2, P.J., Hao1, L., Taylor3, J., Copley1, R., Hein3, J., Moffatt1, M., Cookson1, W.O.C.M.
1Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, England; 2MatTek Corporation, Ashland, MA, United States and 3Oxford Centre for Gene Function, University of Oxford, Oxford, England.
Presented at Society of Investigative Dermatology, St.Louis, MO, May 4-7, (2005).
|
361. |
|
CYTOKINE RELEASE OF A KERATINOCYTE MODEL AFTER INCUBATION WITH TWO DIFFERENT VISCUM ALBUM L EXTRACTS.
Gorter1,2,3,4, R.W., Joller5, P., Stoss1,6, M.
1Medical Section at the Goetheanum, School for Spiritual Science, Dornach, Switzerland; 2International Institute for Oncological and Immunological Research, Cologne, Germany; 3University of California, San Francisco, CA, USA; 4University Witten/Herdecke, Germany; 5PHOENIX-ANAWA, Wangen, Switzerland; 6School of Homeopathy, Technicon of the Witwatersrand, Johannesburg, South Africa.
American Journal of Therapeutics, 10, 40-47, (2003).
|
358. |
|
DEVELOPMENT OF A NOVEL MICRONUCLEUS ASSAY USING THE HUMAN
3-D SKIN MODEL, EPIDERM™.
Curren1, R., Mun1, G., Gibson2, D., Aardema2, M.
1Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA; 2The Procter & Gamble Co., Cincinnati, OH, USA.
Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. The Toxicologist, 84, (1), Abstract # 2209, 453, (2005).
|
357. |
|
EVALUATION OF A TISSUE ENGINEERED HUMAN SKIN EPIDERM™ 3-D CULTURE AS A MODEL TO STUDY IRRITATION AFTER JET FUEL EXPOSURE.
Chatterjee, A., Babu, R., Singh, M.
Florida A&M University, Tallahassee, FL, USA.
Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. The Toxicologist, 84, (1), Abstract # 2004, 410, (2005).
|
355. |
|
LONG TERM REPRODUCIBILITY OF EPIDERM™, AN EPIDERMAL MODEL FOR DERMAL TESTING AND RESEARCH.
Klausner, M., Sheasgreen, J., Kubilus, J., Hayden, P.
MatTek Corporation, Ashland, MA.
Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. The Toxicologist, 84, (1), Abstract # 2191, 449, (2005).
|
354. |
|
HIGH-THROUGHPUT IN VITRO MODELS OF HUMAN EPIDERMIS AND OCULAR EPITHELIUM FOR PRECLINICAL SAFETY AND EFFICACY TESTING OF CONSUMER PRODUCTS AND PHARMACEUTICALS.
Jackson, G., Kubilus, J., Klausner, M., Sheasgreen, J., Hayden, P.
MatTek Corporation, Ashland, MA.
Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. The Toxicologist, 84, (1), Abstract # 2003, 409-410, (2005).
|
350. |
|
QUALITY ASSURANCE FOR IN VITRO ALTERNATIVE TEST METHODS: QUALITY CONTROL ISSUES IN TEST KIT PRODUCTION.
Rispin1, A., Harbell2, J.W., Klausner3, M., Jordan4, F.T., Coecke5, S., Gupta6, K., Stitzel7, K.
1US Environmental Protection Agency, Office of Pesticide Programs (7506C), Washington, DC, USA; 2Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA; 3MatTek Corporation, Ashland, MA, USA; 4Charles River Endosafe Corporation, Wilmington, MA, USA; 5European Centre for the Validation of Alternative Methods, Institute for Health and Consumer Protection, European Commission Joint Research Centre, Ispra, Italy; 6US Consumer Product Safety Commission, Bethesda, MD, USA; 7Consultant, West Chester, OH, USA.
ATLA, 32, (1), 725-729, (2004).
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349. |
|
THE DEVELOPMENT OF AN IN VITRO SCREENING STRATEGY FOR TOPICALLY APPLIED PRODUCTS.
Horan1, I., Clotworthy2, M., Fokunang3, C., Tomkins1, P.
1School of Science (Bioserv Ltd. & CBBR), Athlone Institute of Technology, Athlone, Co. Westmeath, Ireland; 2MRC Laboratory of Molecular Biology, Cambridge, Cambridge, UK; 3School of Plant Sciences, University of Reading, Whiteknights, Reading RG6 6AS, UK.
J. Ethnopharmacol., 89, (1), 81-90, (2003).
|
346. |
|
DERMAL PENETRATION OF PESTICIDES AND POLYCHLORINATED BIPHENYLS FROM HOUSE DUST.
Ertl1, H., Müller2, M., Butte1, W.
1Carl-von-Ossietzky University of Oldenburg, Institute of Pure and Applied Chemistry, Oldenburg, Germany; 2Carl-von-Ossietzky University of Oldenburg, Institute of Biology and Environmental Sciences, Oldenburg, Germany.
|
343. |
|
DEVELOPMENT OF A MICRONUCLEUS ASSAY IN THE EPIDERM™ HUMAN 3D SKIN MODEL.
Curren1, R., Mun1, G., Gibson2, D., and Aardema2, M.
1Institute for In Vitro Sciences, Inc., Gaithersburg, MD; 2The Procter & Gamble Co., Cincinnati, OH.
Presented at the Environmental Mutagen Society Meeting, Pittsburgh, PA. October 2-6, (2004).
|
341. |
|
OPTIMISATION OF THE EPIDERM TEST PROTOCOL FOR THE UPCOMING ECVAM VALIDATION STUDY ON IN VITRO SKIN IRRITATION TESTS.
Kandárová, H., Liebsch, M., Genschow, E., Gerner, I., Traue, D., Slawik, B., Spielmann, H.
Centre for Documentation and Evaluation of Alternative Methods to Animal Experiments (ZEBET) at the BfR (Federal Institute for Risk Assessment), Berlin, Germany.
ALTEX, 21, 107-114, (2004).
|
338. |
|
ASSESSMENT OF SKIN ABSORPTION AND METABOLISM OF ARACHIDONIC ACID & GLYCERYL ARACHIDONATE USING IN VITRO DIFFUSION CELL TECHNIQUES.
Eppler1,2, A.R., Kraeling1, M.E.K., Wickett2, R.L., Bronaugh1, R.L.
1Office of Cosmetics and Colors/ Cosmetic Toxicology Branch, US Food & Drug Administration, Laurel, MD, 2College of Pharmacy, University of Cincinnati, Cincinnati, OH.
Poster Presented at the Society of Toxicology Annual Meeting, Baltimore, MD. March 21-25, (2004).
|
337. |
|
ATTENUATION OF SURFACTANT-INDUCED INTERLEUKIN 1α EXPRESSION BY ZINC PYRITHIONE.
Warren1, R., Schwartz2, J., Sanders2, L., Juneja2, P.
1Winton Hill Technical Center, Procter & Gamble Co., Cincinnati, OH, 2Sharon Woods Technical Center, Procter & Gamble Co., Cincinnati, OH.
Exog Dermatol, 2, (1), 23-27, (2003).
|
336. |
|
ROLE OF TAURINE ACCUMULATION IN KERATINOCYTE HYDRATION.
Janeke*, G., Siefken, W., Carstensen, S., Springmann, G., Bleck**, O., Steinhart*, H., Höger**, P., Wittern, K.P., Wenck, H., Stäb, F., Sauermann, G., Schreiner, V., Doering, T.
R&D cosmed, Beiersdorf AG, Hamburg, Germany; *Department of Food Chemistry and **Department of Dermatology, University of Hamburg, Germany.
J. Invest. Dermatol., 121, (2), 354-361, (2003).
|
335. |
|
EFFECT OF A NEW BOTANICAL EXTRACT BASED ON THE RED ALGAE, PIKEA ROBUSTA, ON IN VIVO REDUCTION OF SURFACTANT-INDUCED SKIN IRRITATION.
Jindal, S., Johnson, C.H., Lods, L.M., Gruber, J.V., Qi, J.
Arch Personal Care Products, LP, 70 Tyler Place, South Plainfield, NJ 07080.
Application Note.
|
334. |
|
CONTRIBUTION OF UVB AND UVA TO UV- DEPENDENT STIMULATION OF CYCLOOXYGENASE-2 EXPRESSION IN ARTIFICIAL EPIDERMIS.
Mahns1,2, A., Wolber2, R., Stäb2, F., Klotz1, L.O., Sies1, H.
1Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, 40225 Düsseldorf, Germany, 2Beiersdorf, Cosmed Forschungszentrum, Unnastraße 48, 20245 Hamburg, Germany.
Photochemistry and Photobiology Science, (3), 257-262, (2004).
|
330. |
|
REINFORCEMENT OF INNATE HOST DEFENSE VIA INDUCTION OF ANTI-MICROBIAL PEPTIDES.
Goyarts, E., Sullivan, M., Muizzuddin,N., Schnittger, S., Mammone, T., Maes, D.
Skin Biology, Estee Lauder Companies, Melville, NY, USA
J. Invest. Dermatol., 122, (3), A79, Abstract #759, (2004).
|
327. |
|
DETECTING REACTIVE OXYGEN SPECIES IN SKIN USING TWO-PHOTON FLUORESCENCE IMAGING MICROSCOPY.
Hanson1, K., Hayden2, P., Kubilus2, J., Clegg1, R.
1Laboratory for Fluorescence Dynamics, Department of Physics, University of Illinois at Urbana-Champaign. 2MatTek Corp. 200 Homer Avenue, Ashland, MA.
J. Invest. Dermatol., 122, (3), A140, Abstract #839, (2004).
|
319. |
|
DISCOVERY OF TRANSDERMAL PENETRATION ENHANCERS BY HIGH-THROUGHPUT SCREENING.
Karande, P., Jain, A. and Mitragotri, S.
Department of Chemical Engineering, University of California, Santa Barbara, CA.
Nature Biotechnology, 22, (2), 192-197, (2004).
|
318. |
|
FLAVONOIDS DIFFERENTIALLY REGULATE IFN-GAMMA-INDUCED ICAM-1 EXPRESSION IN HUMAN KERATINOCYTES: MOLECULAR MECHANISMS OF ACTION.
Bito1,4, T., Roy2, S., Sen2, C.K., Shirakawa3, T., Gotoh3, A., Ueda4, M., Ichihashi4, M., Packer1,5, L.
1 Department of Molecular and Cell Biology, University of California, Berkeley, CA, 2Laboratory of Molecular Medicine, Davis Heart and Lung Research Institute, The Ohio State University Medical Center, Columbus, OH , 3Department of Urology, Kobe University Graduate School of Medicine, Japan, 4Department of Dermatology, Kobe University Graduate School of Medicine, Japan, 5Department of Molecular Pharmacology and Toxicology, School of Pharmacy, University of Southern California, Los Angeles, CA.
FEBS Letters, 520, 145-152, (2004).
|
317. |
|
FOLLOW-UP TO THE ECVAM PREVALIDATION STUDY ON IN VITRO TESTS FOR ACUTE SKIN IRRITATION.
Zuang1, V., Balls1, M., Bothan2, P.A., Coquette3, A., Corsini4, E., Curren5, R.D., Elliott6, G.R., Fentem7, J.H., Heylings2, J.R., Liebsch8, M., Medina9, J., Roguet10, R., van de Sandt11, J.J.M., Wiemann12, C., Worth1, A.P.
1ECVAM, Institute for Health & Consumer Protection, European Commission Joint Research Centre, Italy. 2Syngenta, Central Toxicology Laboratory, Cheshire, UK. 3SGS BioPharma, Wavre, Belgium. 4Laboratory of Toxicology, Milan, Italy. 5Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA. 6TNO-PML, Rijswijk, The Netherlands. 7SEAC Toxicology Unit, Unilever Research, Bedfordshire, UK. 8ZEBET, Berlin, Germany. 9Instituto de Salud Carlos III, Ciudad Unibersitaria, Madrid, Spain. 10L’Oreal Life Sciences Research, Cedex, France. 11TNO Nutrition & Food Research, Zeist, The Netherlands. 12BASF AG, Ludwigshafen, Germany.
ATLA, 30, 109-129 (2002).
|
316. |
|
AN ASSESSMENT OF THE PHOTOTOXIC HAZARD OF A PERSONAL PRODUCT INGREDIENT USING IN VITRO ASSAYS.
Jones, P.A., King, A.V., Earl, L.K., Lawrence, R.S.
Unilever Colworth, Bedfordshire, UK.
Toxicology in Vitro, 17, 471-480, (2003).
|
313. |
|
NALTREXONE AND NALTREXONE-3-O-VALERATE DIFFUSION AND BIOCONVERSION IN A HUMAN EPIDERMIS EQUIVALENT.
Stinchcomb1, A.L., Hammell1, D.C., Stolarczyk1, E.I., Klausner2, M., Hamad1, M., Crooks1, P.A.
1Division of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY, 2MatTek Corporation, Ashland, MA.
Poster presented at the American Association of Pharmaceutical Scientists (AAPS), Salt Lake City, UT, October 26-30, (2003).
|
309. |
|
WOUND HEALING AND EXPRESSION OF ANTIMICROBIAL PEPTIDES/ POLYPEPTIDES IN HUMAN KERATINOCYTES, A CONSEQUENCE OF COMMON GROWTH FACTORS.
Sorenson1,2, O.E., Cowland1, J.B., Theilgaard-Monch1, K., Liu2, L., Ganz2, T. and Borregaard1, N.
1Granulocyte Research Laboratory, Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark. 2Host Defense Research Laboratory, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095.
The Journal of Immunology, 170, 5583-5589, (2003).
|
308. |
|
BY IL-1 SIGNALING, MONOCYTE-DERIVED CELLS DRAMATICALLY ENHANCE THE EPIDERMAL ANTIMICROBIAL RESPONSE TO LIPOPOLYSACCHARIDE.
Liu1, L., Roberts2, A. A., and Ganz1, T.
1Will Rogers Pulmonary Research Laboratory, Departments of Medicine and Pathology. 2Department of Pathology, Geffen School of Medicine, University of California, Los Angeles, CA 90095.
The Journal of Immunology, 170; 575-580, (2003).
|
307. |
|
ASSESSMENT OF THE IN-HOUSE PERFORMANCE OF THE EPIDERM™ AND EPISKIN™ IN VITRO CORROSIVITY TESTS.
Jones, P. and King , A.
Safety and Environmental Assurance Centre, Unilever Colworth, Sharnbrook, Bedford, MK44 1LQ, U.K.
Presented at Eurotox 2003, Florence Italy, September 28-October 1, (2003).
|
306. |
|
A TIERED STRATEGY FOR IN VITRO PHOTOTOXICITY TESTING.
King, A. and Jones, P.
Safety and Environmental Assurance Centre, Unilever Colworth, Sharnbrook, Bedford, U.K.
Presented at EuroTox, Florence, Italy, September 28-October 1 (2003).
|
304. |
|
STUDIES OF BYSTANDER EFFECTS IN ARTIFICIAL HUMAN 3D TISSUE SYSTEMS USING A MICROBEAM IRRADIATION.
Belyakov, O.V., Hall, E.J., Marino, S.A., Randers-Pehrson, G., Brenner, D.J.
Columbia University, Irvington, NY. Center for Radiological Research
(Annual Report), (2002).
|
303. |
|
GENE EXPRESSION PROFILE OF TISSUE ENGINEERED SKIN SUBJECTED TO ACUTE BARRIER DISRUPTION.
Koria1, P., Brazeau2, D., Kirkwood3, K., Hayden4, P., Klausner4, M., Andreadis1, S.
1Department of Chemical Engineering, University at Buffalo, State University of New York, Amherst, NY, 2Department of Pharmaceutical Sciences, University at Buffalo, State University of New York, Amherst, NY, 3Department of Periodontics and Endodontics, University at Buffalo, State University of New York, Amhert, NY, 4MatTek Corportation, Ashland, MA.
J. Investigative Dermatology, 121, (2), 368-382, (2003).
|
301. |
|
IN HUMAN EPIDERMIS, BETA-DEFENSIN 2 IS PACKAGED IN LAMELLAR BODIES.
Oren1,2, A., Ganz1, T., Liu1, L., Meerloo3, T.
1Geffen School of Medicine at University of California, Los Angeles, CA, 2Veterans Administration Medical Center West Los Angeles, Los Angeles, CA, 3University of California at San Diego School of Medicine, San Diego, CA.
Experimental and Molecular Pathology, 74, 180-182, (2003).
|
299. |
|
ASSESSMENT OF HUMAN SKIN IRRITATION: VALIDATION OF IN VITRO MODELS.
MatTek Scientific, Marketing Staff.
MatTek Corporation, Ashland, MA (USA).
May 2003.
|
297. |
|
EVIDENCE THAT NITRIC OXIDE IS AN UPSTREAM MEDIATOR OF FASL-MEDIATED KERATINOCYTE APOPTOSIS IN TOXIC EPIDERMAL NECROLYSIS.
Viard-Leveugle, I., Saurat, J-H., French, L.E.
Dermatology, Geneva University Hospital, Geneva , CH.
J. Invest. Dermatol., 121, (1), Abstract #743, (2003).
|
296. |
|
NOTCH-1 MEDIATED SIGNALING INCREASES IKKα LEVELS - A CRITICAL DETERMINANT CONTROLLING KERATINOCYTE TERMINAL DIFFERENTIATION AND CELL SURVIVAL.
Chaturvedi, V., Qin, J.Z., Denning, M.F., Miele, L., Nickoloff, B.
Pathology, Loyola University Chicago, Maywood, IL, USA.
J. Invest. Dermatol., 121, (1), Abstract #493, (2003).
|
294. |
|
IN VITRO PERCUTANEOUS ABSORPTION USING THE MATTEK EPI-606X SKIN CONSTRUCT AND HUMAN SKIN.
Klausner1, M., Bagley3, D., Harbell2, J., Kubilus1, J., Moyer2, G., Pugh3, G., Raabe2, H.
1MatTek Corp., 2Institute for In Vitro Sciences, 3Colgate-Palmolive Co.
J. Invest. Dermatol., 121, (1), Abstract #574, (2003).
|
290. |
|
COMPARISON OF IN VITRO MODELS OF PERCUTANEOUS ABSORPTION.
Pugh1, G., Raabe2, H., Moyer2, G., Harbell2, J., Bagley1, D.
1Colgate-Palmolive Company, Piscataway, NJ, USA, 2Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA.
Presented at the 2003 Society of Toxicology Meeting.
|
289. |
|
REGULATION OF ANGIOGENESIS FACTORS BY ULTRAVIOLET RADIATION OR HYDROGEN PEROXIDE IN THE EPIDERM IN VITRO SKIN EQUIVALENT.
Last, T.J., Kubilus, J., Klausner, M., Sheasgreen, J. and Hayden, P.
MatTek Corp., Ashland, MA.
Presented at the 2003 Society of Toxicology Meeting.
|
288. |
|
USE OF PROTEOMIC TECHNOLOGIES FOR DISCOVERY OF NEW MARKERS OF SKIN IRRITATION IN VITRO.
Fletcher1, S.T., and Baker2, V.A.
1Safety & Environmental Assurance Centre, Unilever, Bedfordshire, U.K. 2CuDoS Cellular Development Systems Ltd, BioCity Nottingham, U.K.
Presented at 2003 Society of Toxicology Meeting.
|
284. |
|
JAGGED-1 MEDIATED ACTIVATION OF NOTCH SIGNALING INDUCES COMPLETE MATURATION OF HUMAN KERATINOCYTES THROUGH NF-B AND PPARγ.
Nickoloff, B.J., Qin, J., Chaturvedi, V., Denning, M., Bonish, B., and Miele, L.,
Department of Pathology, Loyola University Medical Center, Cardinal Bernardin Cancer Center, IL 60153, USA.
Cell Death and Differentiation 9, 842-855 (2002).
|
283. |
|
RECONSTRUCTED SKIN KITS: REPRODUCIBILITY OF CUTANEOUS IRRITANCY TESTING.
C. Faller, M. Bracher.
Cosmital SA (Research Company of Wella AG, Germany), Marly, Switzerland.
Skin Pharmacology and Applied Skin Physiology 2002;15 (Suppl. 1):74-91.
|
282. |
|
NAD(P)H:QUINONE REDUCTASE ACTIVITY IN HUMAN EPIDERMAL KERATINOCYTES AND RECONSTRUCTED EPIDERMAL MODELS.
Harris, I.R., Siefken, W., Beck-Oldach, K., Wittern, K.P., Pollet, D.
Paul Gerson Unna-Skin Research Center, Beiersdorf AG, Hamburg, Germany.
Skin Pharmacology and Applied Skin Physiology, 15,(Suppl1),68-73.
|
281. |
|
COMPARISON OF ACTIVITIES DEPENDENT ON GLUTATHIONE S-TRANSFERASE AND CYTOCHROME P-450 IA1 IN CULTURED KERATINOCYTES AND RECONSTRUCTED EPIDERMAL MODELS.
Harris, I.R., Siefken, W., Beck-Oldach, K., Brandt, M., Wittern, K.P., Pollet, D.,
Paul Gerson Unna-Skin Research Center, Beiersdorf AG, Hamburg, Germany.
Skin Pharmacology and Apploed Skin Physiology, 15,(Suppl1), 59-67.
|
280. |
|
COMPARISON OF CUTANEOUS BIOAVAILABILITY OF COSMETIC PREPARATIONS CONTAINING CAFFEINE OR ALPHA-TOCOPHEROL APPLIED ON HUMAN SKIN MODELS OR HUMAN SKIN EX VIVO AT FINITE DOSES.
Dreher, F., Fouchard, F., Patouillet, C., Andrian, M., Simonnet, J., Benech-Kieffer, F.
L'Oreal Research, Aulnay-sous-Bois, France.
Skin Pharmacology and Applied Skin Physiology, 15, (Suppl 1), 40-58, (2002).
|
279. |
|
IMPROVEMENT OF THE EXPERIMENTAL SETUP TO ASSESS CUTANEOUS BIOAVAILABILITY ON HUMAN SKIN MODELS: DYNAMIC PROTOCOL.
Dreher F., Patouillet C., Fouchard F., Zanini M., Messager A., Roguet R., Cottin M., Leclaire J., Benech-Kieffer F.
L'Oreal Research, Aulnay-sous-Bois, France.
Skin Pharmacology and Applied Skin Physiology, 15, (Suppl 1), 31-9(2002).
|
278. |
|
PERMEATION AND SKIN ABSORPTION: REPRODUCIBILITY OF VARIOUS INDUSTRIAL RECONSTRUCTED HUMAN SKIN MODELS.
Lotte C., Patouillet C., Zanini M., Messager A., Roguet R.,
Advanced Research Laboratories, L'Oreal Life Sciences, Aulnay-sous-Bois, France.
Skin Pharmacology and Applied Skin Physiology, 15(suppl 1),18-30, (2002).
|
277. |
|
CHARACTERIZATION OF RECONSTRUCTED SKIN MODELS.
Ponec, M., Boelsma, E., Gibbs, S., Mommaas, M.,
Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands.
Skin Pharmacology and Applied Skin Physiology, 15 (Suppl 1), 4-17, (2002).
|
276. |
|
THE USE OF STANDARDIZED HUMAN SKIN MODELS FOR CUTANEOUS PHARMACOTOXICOLOGY STUDIES.
Roguet, R.,
L'Oreal, Life Sciences, Advanced Research Laboratories, Clichy, France.
Skin Pharmacology and Applied Skin Physiology, 15,(Suppl 1),1-3,(2002).
|
275. |
|
RECONSTRUCTED HUMAN EPIDERMIS EQUIVALENTS.
Roguet1, R., Bracher2, M., Diembeck3, W., Ponec4, M.
1L'Oreal, Life Sciences, Advanced Research Laboratories, Clichy, France, 2Cosmital SA (Research Company of Wella AG, Germany), Marly, Switzerland. 3Beiersdorf AG, Hamburg, Germany, 4Humboldt University, Berlin, Germany. 4Department of Dermatology, University Hospital, Leiden, The Netherlands.
Skin Pharmacology and Applied Skin Physiology, 15,(Suppl1)I-III (2002).
|
274. |
|
BARRIER FUNCTION COMPARISON BETWEEN IN VITRO SKIN, ORAL (BUCCAL), AND OCULAR TISSUE MODELS - IMPLICATIONS FOR DRUG DELIVERY STUDIES.
Klausner1, M., Kubilus1, J., Song2, Y., Michniak2, B.,
1Department of Research and Development, MatTek, Ashland, MA, 2Department of Pharmacology and Physiology, UMDNJ-NJMS, Newark, NJ.
Presented at the American Association of Pharmaceutical Scientists Meeting, November (2002).
|
273. |
|
NALTREXONE ESTER PRODRUG BIOCONVERSION IN A HUMAN EPIDERMIS EQUIVALENT.
Stinchcomb1, A., Hammell1, D., Challapalli1, P., Paxton1, E., Swaan2, P., Klausner3, M.,
1University of Kentucky College of Pharmacy, Lexington, KY, 2The Ohio State University College of Pharmacy, Columbus, OH, 3MatTek Corporation, Ashland, MA.
Presented at the American Association of Pharmaceutical Scientists Meeting, November (2002).
|
272. |
|
IMPROVEMENTS IN EPIDERM™, A HIGHLY DIFFERENTIATED SKIN MODEL, FOR DRUG DELIVERY STUDIES
Song1, Y., Klausner2, M., Kubilus2, J., Michniak1, B.,
1Department of Pharmacology and Physiology, UMDNJ-NJMS, Newark, NJ, 2Department of Research and Development, MatTek Corporation, Ashland, MA.
Presented at the American Association of Pharmaceutical Scientists Meeting, Toronto, Canada. November 10-14, (2002).
|
270. |
|
PREDICTIVE ABILITY OF RECONSTRUCTED HUMAN EPIDERMIS EQUIVALENTS FOR THE ASSESSMENT OF SKIN IRRITATION OF COSMETICS.
1Faller, C., 1Barcher, M., 2Dami, N., 2Roguet, R.,
1Cosmital SA (Research Company of Wella AG, Germany), Rte de Chesalles 21, CH-I723 Marly, Switzerland. 2L'Oreal, Life Sciences Research Centre, C. Zviak, rue du General Roguet 90, 92583 Clichy Cedex, France.
Toxicology In Vitro, 16, 557-572, (2002).
Article Summary
|
269. |
|
EVALUATION OF RECONSTRUCTED HUMAN EPIDERMIS KITS FOR THE IN VITRO ASSESSMENT OF COSMETIC SAFETY.
1Roguet R., 3Faller, C., 1Dreher, F., 1Lotte, C., 2Harris, I., 3Bracher, M., 2Pollet, D., 2Pfannenbecker, U., 1Dami, N., 4Ponec, M.,
1L'OREAL Life Sciences Research, France, 2BEIERSDORF AG, R&D Cosmed, Germany, 3WELLA/COSMITAL Department of in Vitro Toxicology, Switzerland, 4University of Leiden, Department of Dermatology, The Netherlands.
Presented at Scandinavian Society of Cosmetic Chemists, Stockholm, Sweden, May (2001).
|
268. |
|
USE OF DIFFERENTIAL DISPLAY-POLYMERASE CHAIN REACTION TO IDENTIFY GENES SELECTIVELY MODULATED BY CHEMICAL ALLERGENS IN RECONSTITUTED HUMAN EPIDERMIS.
1Corsini, E., 2Sheasgreen, J., 1Marmovich, M., and 1Galli, C.,
1Laboratory of Toxicology, Department of Pharmacological Sciences, University of Milan, Milan, Italy, 2MatTek Corporation, Ashland, MA, USA.
Toxicology in Vitro,16,427-431, (2002).
|
265. |
|
PROTEOMIC AND MICROARRAY INVESTIGATION TO IDENTIFY POTENTIAL IN VITRO ENDPOINTS FOR SKIN IRRITATION.
Fletcher1, S.T., Fentem1, J.H., Basketter1, D.A., Kelsell2, M.Philpott2, D.P., and Baker1, V.A.
1SEAC Toxicology, Unilever R&D, Colworth, Bedfordshire, U.K. 2Centre for Cutaneous Research, QMW, University of London, U.K.
Presented at the Annual Meeting of the Society of Investigative Dermatology, Los Angeles, CA, May 15-18, (2002).
|
261. |
|
USE OF EPIDERM™ AS AN INFLAMMATORY MODEL FOR PRE-CLINICAL SCREENING.
Last, T.J., Hayden, P., Burnham, B., Klausner, M., Kubilus, J.
MatTek Corporation, Ashland, MA.
Presented at Soc. Invest. Derm. Meeting, May (2002).
|
260. |
|
EXPRESSION OF CYCLOOXYGENASE IN THE EPIDERM™ HUMAN SKIN MODEL: REGULATION BY ULTRAVIOLET RADIATION AND CYTOKINES.
Hayden, P.J., Last, T.J., Burnham, B., Klausner, M.
MatTek Corporation, Ashland MA.
Presented at Soc. Invest. Derm. Meeting, May (2002).
|
258. |
|
IDENTIFICATION OF POTENTIAL IN VITRO ENDPOINTS FOR SKIN IRRITATION USING PROTEOMIC AND MICROARRAY ANALYSIS.
Fletcher1, S.T., Fentem1, J.H., Basketter1, D.A., Kelsell2, D.P., Philpott2, M., Baker1, V.A.
1SEAC, Unilever, Bedfordshire, United Kingdom , 2Centre for Cutaneous Research, Queen Mary, University of London, United Kingdom.
The Toxicologist, 66 (1-S), 222, Soc. of Toxicol. (Reston, VA), Abstract #1090, (2002).
|
257. |
|
HUMAN β-DEFENSIN-2 PRODUCTION IN KERATINOCYTES IS REGULATED BY INTERLEUKIN-1, BACTERIA, AND THE STATE OF DIFFERENTIATION.
Liu, A., Destoumieux, D., Wong, A., Park, C., Valore, E., Liu, L., Ganz, T.
UCLA School of Medicine.
J. Invest. Dermatol., 118, (2), 275-281, (2002).
|
254. |
|
NEW PERSPECTIVES ON SKIN-COMPATIBLE DETERGENTS FOR SENSITIVE SKIN.
Kremer1, J., Matthies1, W. and Voigtmann2, I.
1Henkel KgaA, Henkelstr. 67, 40191 Dusseldorf. 2Deutscher Allergie- und Asthmabund e. V., Hindenburgstr. 110, 41061 Monchengladbach.
14th Lecture Conference of the GDCH Section "Waschmittelchemie", Wurzburg, Germany, April (2000).
|
252. |
|
ACTIVATION OF NOTCH SIGNALING IN KERATINOCYTES (KC'S) IS NECESSARY AND SUFFICIENT TO CREATE MATURE HUMAN EPIDERMIS.
Nickoloff, B.J., Qin, J., Chaturvedi, V., Denning, M., Banish, B., and Miele, L.
Pathology, Loyola University Chicago, Maywood, IL, USA.
J. Invest. Dermatol., 117, (2), 408, Abstract #110, (2001).
|
251. |
|
CROSS-TALK BETWEEN NOTCH SIGNALING AND TWO PATHWAYS REGULATING EPIDERMAL DIFFERENTIATION.
Chaturvedi, V., Qin, J., Miele, L. and Nickoloff, B.J.
Pathology, Loyola University Chicago, Maywood, IL, USA.
J. Invest. Dermatol., 117, (2), 409, Abstract #116, (2001).
|
250. |
|
CHARACTERIZATION OF APOPTOTIC MACHINERY CONTROLLING CELL DEATH IN EPIDERMIS.
Qin, J.Z., Chaturvedi, V., Denning, M.F., and Nickoloff, B.J.
Pathology, Loyola University Medical Center, Maywood, IL, USA.
J. Invest. Dermatol., 117, (2), 404, Abstract #85, (2001).
|
249. |
|
THE PROTEASE-ACTIVATED RECEPTOR 2 REGULATES PIGMENTATION VIA KERATINOCYTE-MELANOCYTE INTERACTIONS.
Seiberg, M., Paine, C., Sharlow, E., Andrade-Gordon, P., Costanzo, M., Eisinger, M., Shapiro, S.S.
Skin Research Center, Johnson & Johnson CPWW, Skillman, New Jersey, 08558, USA.
Exp. Cell Res., 254(1), 25-32, (2000).
|
247. |
|
APPROACHES FOR THE DEVELOPMENT OF CELL-BASED IN VITRO METHODS FOR CONTACT SENSITIZATION.
Ryan, C.A., Hulette, B.C., Gerberick, G.F.
The Procter & Gamble Company, Miami Valley Laboratories, PO Box 538707, Cincinnati, OH 45253-8707.
Toxicology In Vitro, 15, 43-55, (2001).
|
245. |
|
THE INFLUENCE OF COSMETIC PRODUCTS ON THE STRATUM CORNEUM BY INFRARED AND RAMAN SPECTROSCOPY.
Prasch, Th., Schlotmann, K., Schmidt-Fonk, K., and Forster, Th.
Henkel KgaA, Dusseldorf, Germany.
IFSCC Magazine, 4(3), 201-206, (2001).
|
241. |
|
GENE EXPRESSION ANALYSIS OF EPIDERM™ FOLLOWING EXPOSURE TO SLS USING cDNA MICROARRAYS.
Fletchera, S.T., Bakera, V.A., Fentema, J.H., Baskettera, D.A., Kelsellb, D.P.
aSEAC Toxicology Unit, Unilever Research, Sharnbrook, Bedfordshire MK44 1LQ, UK. bCentre for Cutaneous Research, St Bartholomews and The Royal London School of Medicine and Dentistry, Queen Mary and Westfield College, 2 Newark Street, London E1 2AT, UK.
Toxicology in Vitro, 15, 393-398, (2001).
|
240. |
|
EFFECTS OF CEES ON INFLAMMATORY MEDIATORS, HEAT SHOCK PROTEIN 70A, HISTOLOGY AND ULTRASTRUCTURE IN TWO SKIN MODELS.
Blaha, M., Jr., Bowers, W., Kohl, I., DuBose, D., Walker, J., Alkhyyat, A., Wong, G.
US Army Research Institute of Environmental Medicine, Natick, MA 01760 USA.
J. Appl. Toxicol., 20, S-1, S101-8, (2000).
|
239. |
|
ULTRASTRUCTURAL AND HISTOLOGICAL EFFECTS OF EXPOSURE TO CEES OR HEAT IN A HUMAN EPIDERMAL MODEL.
Blaha1, M., Kohl1, J., DuBose1, D., Bowers, Jr.1, Walker2, J.
1U.S. Army Research Institute of Environmental Medicine and 2U.S. Army Soldier Systems Center, Natick, Massachusetts 01760.
In Vitro & Molecular Toxicology, 14(1), 15-13, (2001).
|
238. |
|
ASSESSMENT OF HUMAN CADAVER AND RECONSTRUCTED SKIN MODELS TO PREDICT PHARMACOKINETICS OF TESTOSTERONE TRANSDERMAL DRUG DELIVERY PATCHES.
Myszka1, S.L.W., Husberg1, M.L., Lawton1, J.M., Lippert1, D.R., Harrison2, L.I.
13M Drug Delivery Systems Division, St. Paul, MN, USA, 55144, 23M Pharmaceuticals Division, St. Paul, MN, USA, 55144.
Presented at The 28th International Symposium on Controlled Release of Bioactive Materials, San Diego, CA, USA June 23-27, (2001).
|
237. |
|
DEVELOPMENT OF AN IN VITRO METHOD FOR SKIN CORROSION TESTING.
Perkins, M.A., Osborne, R., Johnson, O.R.
Procter and Gamble Company.
Fundam. Appl. Toxicol., 31(1), 9-18, (1997).
|
236. |
|
RECONSTITUTED 3-DIMENSIONAL HUMAN SKIN AS A NOVEL IN VITRO MODEL FOR STUDIES OF CARCINOGENESIS.
Zhao, J.F., Zhang, Y.J., Kubilus, J., Jin, X.H., Santella, R.M., Athar, M., Wang, Z.Y., Bickers, D.R.
Biochem. Biophys. Res. Commun., 254(1), 49-53 (1999).
|
235. |
|
EXPRESSION OF PLACENTA GROWTH FACTOR
CYCLOOXYGENASE AND THYMUS-AND ACTIVATION-REGULATED CHEMOKINE IN THE EPIDERM IN VITRO HUMAN SKIN EQUIVALENT.
Hayden, P., Last, T.J., Klausner, M., Kubilus, J.
MatTek Corp. Ashland, MA 01721.
J. Invest. Dermatol., 117, (2), 471, Abstract #490, (2001).
|
234. |
|
MICROARRAY ANALYSIS OF GENE EXPRESSION FOLLOWING EXPOSURE TO SKIN IRRITANTS.
Fletcher, S., Baker, V., Fentem, J., Basketter, D., Kelsell*, D.
SEAC Toxicology, Unilever Research, Shambrook, United Kingdom; *Centre for Cutaneous Research, Queen Mary and Westfield College, London, United Kingdom.
J. Invest. Dermatol., 117, (2) 528, Abstract #832, (2001).
|
233. |
|
TOPICALLY APPLIED LACTIC ACID INCREASES SPONTANEOUS SECRETION OF VASCULAR ENDOTHELIAL GROWTH FACTOR BY HUMAN RECONSTRUCTED EPIDERMIS.
Rendl1, M., Mayer1, C., Weninger1,2, W., Tschachler1,3, E.
1Division of Immunology, Allergy and Infectious Diseases, Department of Dermatology, University of Vienna Medical School, Währinger Gürtel 18–20, A-1090 Vienna, Austria. 2Center for Blood Research, Department of Pathology, Harvard Medical School, Boston, MA, U.S.A. 3Centre de Recherches et Investigation Epidermiques et Sensorielles, Neuilly, France.
British Journal of Dermatology, 145(1), 3-9, (2001).
|
232. |
|
INTERRELATION OF PERMEATION AND PENETRATION PARAMETERS OBTAINED FROM IN VITRO EXPERIMENTS WITH HUMAN SKIN AND SKIN EQUIVALENTS.
Wagner1, H., Kostka2 K-H., Lehr1, C-M., Schaefer1, U.F.
1Department of Biopharmaceutics and Pharmaceutical Technology, Saarland University, D-66123 Saarbruecken, Germany. 2Department of Plastic and Hand Surgery, Caritaskrankenhaus, D-66822 Lebach, Germany.
Journal of Controlled Release, 75(3), 283-295, (2001).
|
231. |
|
COMPARISON OF CUTANEOUS BIOAVAILABILIY OF COSMETIC PREPARATIONS CONTAINING CAFFEINE OR α-TOCOPHEROL APPLIED ON HUMAN SKIN MODELS OR HUMAN SKIN EX VIVO AT FINITE DOSES.
Dreher1, F., Fouchard1, F., Patouillet1, C., Andrian1, M., Simonnet2, J-T., Benech-Kieffer1, F.
1Life Sciences, L'OREAL advanced Research Laboratories, Aulnay-sous-BoisFrance, 2L'OREAL Applied Research, Chevilly-Larue France.
Presented at Gordon Research Conference on "Barrier Function of Mammalian Skin", Bristol, USA, August 5-10, (2001).
|
230. |
|
APPLICATION OF A HUMAN SKIN TISSUE CULTURE MODEL IN DERMAL ABSORPTION STUDIES OF 3,3’,4,4-TETRACHLOROBIPHENYL (TCB).
Oiao1, G.L., Riviere2, J.E.
1Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV. 2Center for Cutaneous Toxicology and Residue Pharmacology, North Carolina State University, Raleigh, NC, USA.
The Toxicologist, 54 (1), 150, Soc. of Toxicol. (Reston, VA), Abstract #707, (2000).
|
229. |
|
AVOCADO PHYTOSTEROLS DECREASE UVB-INDUCED PRO-INFLAMMATORY MEDIATORS.
Joseph, L.B., Koukouras, K.
Corda, Inc., NATC, Edison, NJ.
J. Invest. Dermatol., 117, (2), 501, Abstract #667, (2001).
|
228. |
|
AN IN VITRO METHOD FOR SCREENING ANTI-IRRITANTS ON UV AND CHEMICALLY TREATED, RECONSTITUTED, THREE DIMENSIONAL HUMAN SKIN.
Majmudar, G., Fisher, L.
Mary Kay Holding Corp., Dallas, Texas.
J. Invest. Dermatol., 117, (2), 459, Abstract #415, (2001).
|
224. |
|
EVALUATION OF THE USEFULNESS OF 3-D MODELS OF RECONSTITUTED HUMAN SKIN AND EPIDERMIS IN APPLICATIONS OF REGULATORY SKIN TOXICOLOGY: PREVALIDATION, VALIDATION, CATCH-UP VALIDATION, AND REGULATORY ACCEPTANCE.
Liebsch, M.
ZEBET BgVV, National Center for Evaluation and Validation of Alternatives to Animal Experiments, D-12277, Berlin, Germany.
In Vitro Cell. Dev. Biol – Animal, 37, (3), (2001).
|
223. |
|
HUMANE ENDPOINTS AND ACUTE TOXICITY TESTING.
Sass, N.
Alabama Department of Public Health, Montgomery, Alabama, USA.
ILAR Journal, 41(2), 14-23, (2000).
|
222. |
|
IN VITRO AND HUMAN TESTING STRATEGIES FOR SKIN IRRITATION.
Robinson, M.K., Osborne, R., Perkins, M.A.
The Procter & Gamble Company, Miami Valley Laboratories, Cincinnati, Ohio 45253-8707.
Ann. NY Acad. Sci., 919, 192-204 (2000).
|
221. |
|
RECONSTRUCTED SKIN EQUIVALENTS FOR ASSESSING PERCUTANEOUS DRUG ABSORPTION FROM PHARMACEUTICAL FORMULATIONS.
Zghoul, N., Fuchs, R., Lehr, C.M., Schaefer, U.F.
Dept. of Biopharmaceutics and Pharmaceutical Technology, Saarland University, D-Saarbrucken.
Altex, 18(2), 103-6, (2001).
|
219. |
|
STRATEGIES FOR THE ASSESSMENT OF ACUTE SKIN IRRITATION POTENTIAL.
Robinson, M., Osborne, R., Perkins, M.A.
Procter & Gamble Co., Miami Valley Labs, PO Box 538707, Cincinnati Ohio 45253-8707
Journal of Pharmacological and Toxicological Methods, 42, 1-9, (1999).
|
217. |
|
EFFECTS OF ANTIOXIDANT INGREDIENTS ON HUMAN SKIN: FROM CELL CULTURE TESTING TO HUMAN CLINICAL TRIALS.
Green1, J., Roberts2, R.
1Shaklee Corporation, Hayward, CA and 2R.L. Roberts and Associates, Germantown, TN.
Journal of Cosmetic Science, 51, (1) 42-43, (2000).
|
216. |
|
EVALUATION OF HUMAN BIO-ENGINEEREED SKIN EQUIVALENT FOR DRUG PERMEATION STUDIES.
Asbill, C., Kim, N., El-Kattan, A., Creek, K., Wertz, P., Michniak, B.
Department of Basic Pharmaceutical Science, College of Pharmacy, University of South Carolina.
Pharmaceutical Research, 17, (9) 1092-7, (2000).
|
215. |
|
PERCUTANEOUS PERMEATION OF ZINC FROM NON-WOVEN FABRICS IMPREGNATED WITH ZINC SULFATE MONOHYDRATE FORMULATIONS USING EPIDERM™.
El-Kattan, A., Michniak, B.
Department of Basic Pharmaceutical Science, College of Pharmacy, University of South Carolina.
Presented at the 6th World Biomaterials Congress in Kumuela, Hawaii, May 15-20, (2000).
|
214. |
|
LIPID AND ULTRA-STRUCTURAL CHARACTERIZATION OF RECONSTRUCTED SKIN MODEL.
Ponec, M., Boelsma, E., Weerheim, A., Mulder, A., Bouwstra, J., Mommaas, M.
Leiden University, Leiden, The Netherlands
International J. of Pharmaceutics, 203, 211-225, (2000).
|
213. |
|
RECONSTRUCTED HUMAN SKIN EQUIVALENTS-THEIR VALUE FOR SCREENING OF SKIN IRRITATION.
Esther Boelsma
Thesis University Leiden, Leiden, The Netherlands.
ISBN 90-9012744-5, (1999).
|
212. |
|
IN VITRO TESTING FOR PHOTOTOXIC POTENTIAL USING THE EPIDERM 3-D RECONSTRUCTED SKIN MODEL.
Jones, P., Lovell, W., King, A., Earl, L.
Unilever Research.
Toxicology Methods, 11, (1) 1-19, (2001).
|
210. |
|
HIGHLY DIFFERENTIATED SKIN EQUIVALENT MODEL FOR HIGH THROUGHPUT SCREENING OF TOPICAL THERAPEUTICS.
Hayden, P., Jackson, R., Klausner M., Kubilus, J.
MatTek Corp., Ashland, MA.
J. Invest. Dermatol., 115, (3) 589, Abstract #359, (2001).
|
209. |
|
A REPRODUCIBLE SKIN MODEL FOR DERMAL SAFETY AND EFFICACY TESTING.
Klausner, M., Kubilus, J., Hayden, P., Sheasgreen, J.
MatTek Corp., Ashland, MA.
The Toxicologist, 60 130, Soc. of Toxicol. (Reston, VA), Abstract #622, (2001).
|
208. |
|
RANTES, GRO-α, TNF-α RELEASE FROM IN VITRO EPIDERMIS MODELS FOLLOWING TREATMENT OF STAPHLOCOCCAL ENTEROTOXIN A.
Yamada, H., Yudate, T., Matukura, M., Tezuka, T.
University School of Medicine, Osaka, Japan.
Presented at the 22nd Annual Meeting of the Japanese Soc. for Investigative Dermatology, Osaka, Japan, September 4-5, (1997).
Online.
|
207. |
|
DERMATACS™ IN SITU APOTOSIS DETECTION KIT FOR SKIN CELLS AND TISSUES.
Trevigen, Inc.
Trevigen Press Release (2000).
Online: DermaTACS.
|
205. |
|
A REPRODUCIBLE, STRUCTURALLY APPROPRIATE SKIN MODEL FOR DERMAL SAFETY AND EFFICACY TESTING.
Klausner, M., Sheasgreen, J., Hayden, P., Liebsch1, M., Kubilus, J.
MatTek Corp., Ashland, MA, 01721, USA; 1ZEBET, Berlin, Germany.
Presented at the 21st International Federation of Societies of Cosmetic Chemists Congress, Berlin, Germany, September 11 – 14, (2000).
|
204. |
|
TERMINAL DIFFERENTIATION OF HUMAN KERATINOCYTES AND STRATUM CORNEUM FORMATION IS ASSOCIATED WITH CASPASE-14 ACTIVATION.
1Eckhart, L., Declercq2, W., Ban1, J., Rendl1, M., Mayer1, C., Lippens2, S., Vandenabeele2, P., Tschachler1,3, E.
1Division of Immunology, Allergy and Infectious Diseases, Department of Dermatology, University of Vienna Medical School, Vienna, Austria, 2Molecular Signaling and Cell Death Unit, Department of Molecular Biology, Flanders Interuniversity Institute for Biotechnology and Gent University, Gent, Belgium. 3Centre de Recherches et d’Investigations Epidermiques et Sensorielles (CE.R.I.E.S.), Neuilly, France.
J. Invest. Dermatol., 115, (6), 1148-1151, (2000).
|
203. |
|
IL-1-RELATED CYTOKINE RESPONSES OF NONIMMUNE SKIN CELLS SUBJECTED TO CEES EXPOSURE WITH AND WITHOUT POTENTIAL VESICANT ANTAGONISTS.
Blaha1, M., Bowers, Jr.1, W., Kohl1, J., DuBose1, D., Walker2, J.
1U.S. Army Research Institute of Environmental Medicine. 2U.S. Army Soldier and Biological Chemical Command, Natick, MA 01760.
In Vitro & Molecular Toxicology, 13, (2), 99, (2000).
|
201. |
|
RECONSTRUCTED EPIDERMAL MODELS AS A POSSIBLE ALTERNATIVE TO THE USE OF EXCISED HUMAN SKIN FOR ASSESSING IN VITRO PERCUTANEOUS ABSORPTION.
Zghoul, N., Wagner, H., Lehr, C-M., Schaefer, U.
Department of Biopharmaceutics and Pharm. Technology, Saarland University D-66123 Saarbruecken, Germany.
|
199. |
|
CHARACTERIZATION AND COMPARISON OF RECONSTRUCTED SKIN MODELS: MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL EVALUATION.
Boelsma1, E., Gibbs1, S., Faller 2, C., Ponec1, M.
1Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands and 2Department of In Vitro Toxicology, Laboratory of Cytotoxicity and Irritation, COSMITAL SA, Marly, Switzerland
Acta Derm Venereol, 80, 82-88, (2000).
|
198. |
|
INHIBITION OF UV INDUCED MMP-1 IN EPIDERMAL EQUIVALENTS BY ANTIOXIDANTS.
Martin, K.M., Lyte, P., Mazuruk, K., Shapiro, S.
Skin Research Center, Johnson & Johnson Consumer Products Worldwide, Skillman, New Jersey.
J. of Invest. Dermatol., 114, 803, Abstract #309, (2000).
|
197. |
|
CHANGES IN CANCER-RELATED GENE EXPRESSION IN AN IN VITRO HUMAN SKIN MODEL FOLLOWING UVB-IRRADIATION.
Hayden, P.J., Klausner, M., Kubilus, J.
MatTek Corp., Ashland, Massachusetts
J. of Invest. Dermatol., 114, 824, Abstract #449, (2000)
|
195. |
|
USE OF DIFFERENTIATED EPIDERMAL CULTURES FOR THE EXAMINATION OF INFANT-FECES-INDUCED SKIN IRRITATION.
Hendrix, S.W.
Procter and Gamble, Cincinnati, Ohio.
J. of Invest. Dermatol., 114, 836, Abstract #519, (2000).
|
194. |
|
WOUNDING UPREGULATES VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION BY KERATINOCYTES OF IN VITRO RECONSTRUCTED HUMAN EPIDERMIS.
Rendl, M., Mayer, C., Fischer, H., Pammer*, J., Weninger, W., Tschachler, E.
DIAID, Department of Dermatology, University of Vienna Medical School, Vienna, Austria, *Institute of Clinical Pathology, University of Vienna Medical School, Vienna, Austria
J. of Invest. Dermatol., 114, 855, Abstract #636, (2000).
|
193. |
|
LACK OF PHOTOTOXICITY OF COSMETIC FORMULATIONS CONTAINING GLYCOLIC ACID IN AN IN VITRO HUMAN SKIN MODEL.
Jones1, B.C., Raabe2, H.A., Sizemore2, A., Mun2, G.C., Theophilus1, E.H., Dickens1, M.S.
1Avon Products, Inc., Suffern, NY, 2Institute for In Vitro Sciences, Inc., Gaithersburg, MD
Toxicological Sciences, 54, (1), 394-5, Abstr. #1853 (2000).
|
192. |
|
PREVALIDATION OF THE EPIDERM PHOTOTOXICITY TEST (ED-PT).
Liebsch1, M., Traue1, D., Barrabas1, C., Spielmann1, H., Gerberick2, F., Cruse2, L., Diembeck3, W., Pfannenbecker3, U., Spieker3, J., Hottzhutter3, H., Brantom5, P., Aspin5, P., Southee6, J.
1ZEBET BgVV, Berlin, Germany, 2Procter & Gamble Co., Cincinnati, OH, 3Beiersdorf AG, Hamburg, Germany, 4Humboldt University, Berlin, Germany, 5BIBRA International, Carshalton, United Kingdom, 6MA Bioservices, Richmond, United United Kingdom
Toxicological Sciences, 54, (1), 379, Abstr. #1777 (2000).
|
189. |
|
HIGHLY DIFFERENTIATED IN VITRO SKIN MODEL FOR HIGH THROUGHPUT SCREENlNG OF TOPICAL THERAPEUTICS.
Hayden, P.J., Jackson, Jr., G.R., Klausner, M., Kubilus, J.
MatTek Corp., Ashland, MA 01721.
Toxicological Sciences, 54, (1), 146, Abstr. #688 (2000).
|
188. |
|
THE PROTEASE-ACTIVATED RECEPTOR 2 REGULATES PIGMENTATION VIA KERATINOCYTE-MELANOCYTE INTERACTIONS.
Seiberg, M., Paine, C., Sharlow, E., Andrade-Gordon, P., Costanzo, M., Eisinger, M., Shapiro, S.S.
Skin Research Center, Johnson & Johnson CPWW, Skillman, NJ, 08558 USA.
Exp. Cell Res., 254(1), 25-32, (2000).
|
187. |
|
IL-1α AND IL-1ra SECRETION FROM EPIDERMAL EQUIVALENTS AND THE PREDICTION OF THE IRRITATION POTENTIAL OF MILD SOAP AND SURFACTANT-BASED CONSUMER PRODUCTS.
Bernhofer1, L.P., Barkovic2, S., Appa2, Y., Martin1*, K.M.
1Skin Research Center, Johnson & Johnson Consumer Products Worldwide, 199 Grandview Road, Skillman, NJ 08558, 2Neutrogena Corporation, 5760 West 96th Street, Los Angeles, CA 90045, USA.
Toxicology in Vitro, 13, 231-239, (1999).
|
186. |
|
THE INFLUENCE OF THE RESPONSE OF SKIN EQUIVALENT SYSTEMS TO TOPICALLY APPLIED CONSUMER PRODUCTS BY EPITHELIAL-MESENCHYMAL INTERACTIONS.
Bernhofer, L.P., Seiberg, M., Martin, K.M.
Skin Research Center, Johnson & Johnson Consumer Products Worldwide, 199 Grandview Road, Skiliman, NJ 08558, USA.
Toxicology in Vitro, 13, 219-229, (1999).
|
184. |
|
ASSESSMENT OF THE IRRITATION POTENTIAL OF TOPICAL S | | |
