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Data Sheet Specification Sheet Technical References
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EpiAirway Technical References

100.

In order to facilitate the literature review process, the Abstract Pak contains the abstract portions of the listed posters and publications. Keywords: Dendritic Cells, EpiAirway, EpiDerm, EpiDerm-201, EpiDermFT,...[more]

Category: Technical References, DendriticCells, EpiAirway, EpiDerm, EpiDerm-201, EpiDermFT, EpiOcular, EpiOral, EpiVaginal, MelanoDerm

156. RECONSTRUCTED, DIFFERENTIATED AIRWAY EPITHELIAL CULTURES TO MODEL RESPIRATORY INFECTION.

Klausner1, M., Kubilus1, J., Ogle1, P., Adamou2, J.E., Langermann2, S. 1MatTek Corp., Ashland, MA 01721, 2MedImmune Incorporated, Gaithersburg, MD 20878. Presented at the Lovelace Respiratory Research Institute symposium, ...[more]

Category: Technical References, EpiAirway

168. RECONSTRUCTED, DIFFERENTIATED AIRWAY EPITHELIAL CULTURES TO DETECT OCCUPATIONAL ASTHMA CAUSING AGENTS.

Sheasgreen, J., Klausner, M., Kubilus, J., Ogle, P. MatTek Corp., Ashland, MA. USA. The Toxicologist, 48 (1-S), 126, Soc. of Toxicology (Reston, VA), Abstract #594, (1999). Summary: Normal human tracheal-bronchial...[more]

Category: Technical References, EpiAirway

225. CHARACTERIZATION OF INFLAMMATORY MEDIATOR RELEASE FROM AN IN VITRO HUMAN BRONCHIAL/TRACHEAL EPITHELIAL TISSUE MODEL.

Hayden, P., Jackson, R., Klausner, M., Kubilus, J. MatTek Corp., Ashland, MA. Presented at the Lovelace Respiratory Research Institute International Symposium, Santa Fe, NM, October 3, (2000). Summary: Inflammatory...[more]

Category: Technical References, EpiAirway

242. CHARACTERIZATION OF INFLAMMATORY MEDIATOR RELEASE FROM AN IN VITRO HUMAN TRACHEAL/BRONCHIAL EPITHELIAL TISSUE MODEL.

Hayden, P., Jackson, R., Last, T.J., Klausner, M. and Kubilus, J. MatTek Corp., Ashland, MA 01721. The Toxicologist, 60 (1), 425, Soc. of Toxicol. (Reston, VA), Abstract #2023, (2001). Summary: Monolayer cultures of...[more]

Category: Technical References, EpiAirway

243. PERMEABILITY AND CYTOTOXICITY OF MACROMOLECULE FROM NASAL FORMULATION USING EPIAIRWAY TISSUE MODEL.

El-Shafy, M.A., Roemer, E., deMeireles, J., Biswas, M., Quay, S.C. Nastech Pharmaceutical Company, Hauppauge, NY, USA. AAPSPharmSci, Vol. 3, No. 3, S-58, (2001). Summary: Hydrophilic macromolecules such as proteins and...[more]

Category: Technical References, EpiAirway

244. EFFECTS OF ENHANCERS ON MACROMOLECULES FORMULATIONS ON MEMBRANE PENETRATION, CELL VIABILITY AND RESISTANCE USING EPIAIRWAY™ TISSUE MODEL.

Quay, S.C., deMeireles, J., Wormuth, D., Vangalla, S., and Biswas, M. Nastech Pharmaceutical Company, Hauppauge, NY, USA. AAPSPharmSci, Vol. 3, No. 3, S-57, (2001). Summary: Drug delivery by the nasal route provides...[more]

Category: Technical References, EpiAirway

256. EXPRESSION OF 15-LIPOXYGENASE-2 IN THE EPIAIRWAY™ IN VITRO HUMAN TRACHEAL/BRONCHIAL EPITHELIAL MODEL: REGULATION BY TNF-α AND INF-γ.

Hayden1, P.J., Jackson1, G.R., Last1, T.J., Klausner1, M., Kubilus1, J., Shappell2, S.B. 1MatTek Corp., Ashland, MA, 2Department of Pathology, Vanderbilt University School of Medicine, Nashville, TN. The Toxicologist, 66...[more]

Category: Technical References, EpiAirway

267. TUMOR NECROSIS FACTOR ALPHA (TNFα) INDUCTION OF THYMUS AND ACTIVATION REGULATED CHEMOKINE (TARC) EXPRESSION IS MEDIATED BY 15-LIPOXYGENASE 15-(LOX)-2 IN THE EPIAIRWAY™ HUMAN TRACHEAL/BRONCHIAL EPITHELIAL MODEL.

Jackson1, G.R., Last1, T.J., Klausner1, M., Kubilus1, J., Shappell2, S.B., Brash2, A.R. and Hayden1, P. 1MatTek Corporation, Ashland, MA USA, and 2Department of Pathology, Vanderbilt University School of Medicine,...[more]

Category: Technical References, EpiAirway

271. AN IN VITRO MODEL FOR THE RAPID SCREENING OF POTENTIAL COMPONENTS AND FORMULATIONS FOR NASAL DRUG DELIVERY.

Scotto-Lavino, E., Easow, J., Simon, S., and Roemer, E., State University of New York (SUNY) at Stony Brook, Stony Brook, NY. In Vitro Cellular and Developmental Biology, 38, 12A (2002). Summary: Clinical trials have...[more]

Category: Technical References, EpiAirway

298. REPRODUCIBILITY OF EPIAIRWAY™, A DIFFERENTIATED AIRWAY TISSUE MODEL FOR PRE-CLINICAL DRUG DEVELOPMENT STUDIES.

Patrick J. Hayden, Mitchell Klausner, Joseph Kubilus, Robert Jackson, Elizabeth J. Roemer1. MatTek Corporation, Ashland, MA 01721, 1State University of New York at Stony Brook, Stony Brook, NY, 11794. Presented at the...[more]

Category: Technical References, EpiAirway

300. IN VITRO MODELS OF FULL-THICKNESS HUMAN SKIN (EPIDERMFT™) AND AIRWAY EPITHELIUM (EPIAIRWAYFT™) FOR TOXICOLOGY AND DRUG DEVELOPMENT APPLICATIONS.

P.J. Hayden, M. Klausner, J. Kubilus, B. Burnham and G.R. Jackson. MatTek Corporation, Ashland, MA 01721. Presented at the 2003 Congress on In Vitro Biology, Portland, OR (May 31-June 4) Summary: In vitro models of human...[more]

Category: Technical References, EpiDermFT, EpiAirway, EpiAirwayFT

304. STUDIES OF BYSTANDER EFFECTS IN ARTIFICIAL HUMAN 3D TISSUE SYSTEMS USING A MICROBEAM IRRADIATION.

Belyakov, O.V., Hall, E.J., Marino, S.A., Randers-Pehrson, G., Brenner, D.J. Columbia University, Irvington, NY. Center for Radiological Research (Annual Report), (2002). Summary: According to the target theory of ...[more]

Category: Technical References, EpiDerm, EpiAirway, EpiOcular

310. DEVELOPMENT OF AN INTRANASAL FORMULATION OF THE Y2R AGONIST PEPTIDE YY3-36.

Kleppe, M., Deshpande, A., Go, Z., Constantino, H.R., Sileno, A., Brandt, G., Lee*, M., Quay, S. Nastech Pharmaceuticals, Bothell, WA and *UCLA, Los Angeles, CA. Summary: Peptide YY (PYY) was identified in the 1980s as a...[more]

Category: Technical References, EpiAirway

314. DOPAMINE TRANSPORT ACROSS RESPIRATORY EPITHELIUM.

Chemuturi1, N., Donovan1, M., Klausner2, M., and Hayden2, P. 1College of Pharmacy, University of Iowa, Iowa City, IA. 2MatTek Corporation, Ashland, MA. Poster presented at the American Association of Pharmaceutical...[more]

Category: Technical References, EpiAirway

315. DRUG PERMEABILITY ACROSS BOVINE RESPIRATORY TISSUES COMPARED TO A HUMAN TRACHEO/BRONCHIAL CELL CULTURE (EPIAIRWAY™ SYSTEM).

Chemuturi1, N., Donovan1, M., Klausner2, M., and Hayden2, P. 1College of Pharmacy, University of Iowa, Iowa City, IA. 2MatTek Corporation, Ashland, MA. Poster presented at the American Association of Pharmaceutical...[more]

Category: Technical References, EpiAirway

331. PERMEATION OF WIN 55,212-2, A POTENT CANNABINOID RECEPTOR AGONIST, ACROSS HUMAN TRACHEO-BRONCHIAL TISSUE (EPIAIRWAY™) IN VITRO AND RAT NASAL EPITHELIUM IN VIVO.

Agu1, R.U., Valiveti1, S., Paudel1, K.S., Klausner2, M., Hayden2, P.J., Stinchcomb1, A.S. 1University of Kentucky College of Pharmacy, Lexington, KY, 2MatTek Corporation, Ashland, MA. Journal of Pharmacy and Pharmacology,...[more]

Category: Technical References, EpiAirway

332. AN IN VITRO MODEL OF FULL-THICKNESS HUMAN AIRWAY EPITHELIUM (EPIAIRWAY-FT) FOR STUDY OF EPITHELIUM/MATRIX INTERACTIONS.

Hayden, P. J., Klausner, M., Kubilus, J., Burnham, B., Jackson, G. R. MatTek Corporation, Ashland, MA. Presented at the American Thoratic Society Meeting, Orlando, FL, May 21-26, (2004). Summary: In vitro models of airway...[more]

Category: Technical References, EpiAirway

344. CANNABIDIOL DIFFUSION ACROSS HUMAN TRACHEO-BRONCHIAL TISSUE (EPIAIRWAY™) AND INTRANASAL ABSORPTION IN RATS.

Agu1, R., Valiveti1, S., Paudel1, K., and Klausner2, M., Hayden2, P. University of Kentucky College of Pharmacy, Lexington, KY; 2MatTek Corporation, Ashland, MA. Presented at American Association of Pharmaceutical...[more]

Category: Technical References, EpiAirway

345. LOCALIZATION OF P-GLYCOPROTEIN IN HYMAN TRACHEAL/BRONCHIAL EPITHELIAL CELL CULTURE (EPIAIRWAY™)

Chemuturi1, N., Hayden2, P., Klausner2, M., Donovan1, M. 1Division of Pharmaceutics, The University of Iowa, Iowa City, IA; 2MatTek Corporation, Ashland, MA. Presented at American Association of Pharmaceutical Scientists...[more]

Category: Technical References, EpiAirway

347. THE USE OF FLUORESCENTLY LABELED NANOPARTICLES TO DETERMINE THE EFFECT OF PARTICLE SIZE ON TRANSLOCATION FROM THE LUNG.

Carter1, J.M., Kennedy1, J.M., Oberdorster2, G., Clark3, E.D. 1The Procter & Gamble Co., Cincinnati, OH; 2University of Rochester, Rochester, NY; 3The Health and Environmental Safety Alliance, Cincinnati, OH. Presented...[more]

Category: Technical References, EpiAirway

351. A HIGH-THROUGHPUT IN VITRO MODEL OF HUMAN TRACHEAL/ BRONCHIAL EPITHELIUM (EPIAIRWAY™) FOR PRE-CLINICAL SAFETY AND EFFICACY TESTING OF PHARMACEUTICALS.

Hayden, P.J., Jackson, G., Kubilus, J., Sheasgreen, J., Klausner, M. MatTek Corporation, Ashland, MA. Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. The Toxicologist, 84, (1), Abstract...[more]

Category: Technical References, EpiAirway

359. IDENTIFICATION OF INTELLIGENT BIOMARKERS OF EXPOSURE AND HARM IN THE RESPIRATORY EPITHELIAL TO TOBACCO SMOKE COMPONENTS.

BéruBé, K., Sexton, K., Jones, T. School of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3US, Wales, UK. Summary: This study by researchers in the Cardiff University School of Biosciences (Wales/UK)...[more]

Category: Technical References, EpiAirway

368. INTRANASAL DELIVERY OF RECOMBINANT HUMAN PARATHYROID HORMONE [HPTH (1–34)], TERIPARATIDE IN RATS.

Agu1, R.U., Valiveti1, S., Earles1, D.C., Klausner2, M., Hayden2, P.J., Wermeling1,3,D.P., Stinchcomb1, A.L. 1College of Pharmacy, University of Kentucky, Lexington, Kentucky, USA; 2MatTek Corporation, Ashland, Massachusetts,...[more]

Category: Technical References, EpiAirway

370. MICROARRAY EXPRESSION STUDIES ON AN IN VITRO MODEL OF HUMAN AIRWAY EPITHELIUM (EPIAIRWAY).

Moffatt1, M.F., Hill1, A.L., Hao1, L., Taylor2, J., Hayden3, P.J., Cookson1, W.O.C.M. 1Wellcome Trust Centre for Human Genetics, University of Oxford, U.K; 2Department of Statistics, Oxford Centre for Gene Function, University...[more]

Category: Technical References, EpiAirway


Dendritic (Langerhans) Cells
EpiAirway Normal Human Airway Tissue Model
EpiDerm Reconstructed Human Epidermis (RhE) Tissue Model
EpiDerm-201 Under-developed Skin Model
EpiDermFT™ Skin Model
EpiOcular Normal Human Corneal Tissue Model
EpiOral Normal Human Buccal, EpiGingival Normal Human Gum Tissue Models
EpiVaginal Normal Human Ecto-Cervical Vaginal Tissue Model
MelanoDerm Normal Human Skin Model with Melanocytes
Melanoma Skin Model
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