New MatTek Technical References December 2009

Listed below are the MatTek In Vitro Product Technical References added to the Web site in DECEMBER 2009. Click on the technical reference TITLE to review full citation information as well as a detailed summary.

• THE EFFICACY OF ECHINACEA IN A 3-D TISSUE MODEL OF HUMAN AIRWAY EPITHELIUM.
  
  SUMMARY:
  This study by researchers at the University of British Columbia and A. Vogel Bioforce AG demonstrated that MatTek’s EpiAirway in vitro 3-D human tracheal/bronchial tissue equivalent can be infected with rhinovirus type 1A (RV1A) and then used to evaluate the antirhinovirus efficacy of Echinacea purpurea.
  
  
  
• DAS181, A SIALIDASE FUSION PROTEIN, PROTECTS HUMAN AIRWAY EPITHELIUM AGAINST INFLUENZA VIRUS INFECTION: AN IN VITRO PHARMACODYNAMIC ANALYSIS.
  
  SUMMARY:
  This study by researchers at NexBio and the University of Hong Kong demonstrated that MatTek’s EpiAirway in vitro 3-D human tracheal/bronchial tissue equivalent can be used to model the pharmacodynamics of a new drug formulation that inhibits influenza virus infection.
  
  
  
• HIV TYPE 1 FAILS TO TRIGGER INNATE IMMUNE FACTOR SYNTHESIS IN DIFFERENTIATED ORAL EPITHELIUM.
  
  SUMMARY:
  This study by scientists at Prince of Songkla University (Thailand), the University of Washington, Fred Hutchinson Cancer Research Center and MatTek Corp. demonstrated that MatTek’s EpiOral in vitro 3-D human buccal (inner cheek) tissue equivalent can be used to model the in vivo response to HIV-1 virus exposure.