New MatTek Technical References
November 2009
Listed below are the MatTek In Vitro Product Technical References added to the Web site in NOVEMBER 2009. Click on the technical reference TITLE to review full citation information as well as a detailed summary.
- IMPROVING GENOTOXICITY TESTING: COMET ASSAY WITH 3D SKIN MODELS.
SUMMARY:
This study by scientists at Henkel, ECVAM, TNO, L'Oreal, COLIPA, Procter and Gamble - Cosmital SA, Unilever, Procter and Gamble US, Beiersdorf, KPSS (Kao Professional Salon Services), GlaxoSmithKline (GSK) and Pierre Fabre demonstrated that MatTek’s EpiDerm in vitro 3-D human skin tissue equivalent can be used in a test system of higher biological relevance compared to currently used monolayer cultures for COMET (genotoxicity) testing of cosmetics and their ingredients.
- AccelaFuze™ PEPTIDE INFUSION THERAPY.
SUMMARY:
This study by scientists at Woodford Medical Aesthetics demonstrated that MatTek’s EpiDermFT full-thickness in vitro 3-D human skin tissue equivalent, because it is produced from normal (non-transformed) human skin cells (keratinocytes and fibroblasts), can be used to accurately measure the specific gene expression changes produced by new topical skin treatments before they are tested on humans.
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