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Dendritic Cells

EpiAirway^TM

EpiDerm^TM

EpiDermFT^TM

EpiOcular^TM

EpiOral^TM

EpiVaginal^TM

MelanoDerm^TM

Melanoma



MatTek Corporation
200 Homer Avenue
Ashland, MA  01721
508-881-6771
FAX:  508-879-1532
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MatTek Presentations -
7th World Congress on
Alternatives & Animal Use
in the Life Sciences (WC7)

The 7th World Congress on Alternatives and Animal Use in the Life Sciences will take place in Rome, Italy 30 August to 3 September 2009.

The Congress was given the motto "Calling on Science" in order to emphasize that scientific progress today goes hand in hand with progress towards the reduction, refinement and replacement of experimental animals (The Three Rs).

MatTek Corp. scientists have authored or co-authored twelve (12) Technical Presentations including two (2) Platform Presentations.

Platform Presentations:

• "In vitro phototoxicity studies with reconstructed human skin equivalents"
  
  Presenter: Helena Kandarova
  Wednesday, 2 September 2009
  Skin and eye toxicity I
  Time: 10:00-12:30
  Room: Auditorium
  
  
• "ECVAM validation drives EpiOcular™ expanded applicability domain for European legislation relevant test articles: successful international pre-validation"
  
  Presenter: Patrick J. Hayden
  Wednesday, 2 September 2009
  Skin and eye toxicity II (BS22)
  Time: 14:45 - 17:15
  Room: Auditorium
  
  

Technical Poster Presentations:

Please click on the links below to review the presentation abstracts (PDF format).

• VALIDATION OF AN IN VITRO SKIN IRRITATION TEST PROTOCOL (EPIDERM-SIT) TO REPLACE THE IN VIVO RABBIT TEST FOR HAZARD IDENTIFICATION OF CHEMICALS
  (ID ABS: 180 / Poster Section: PO 10)
  
  EpiDerm SIT Training VIDEO
  
  
• COLIPA'S INDUSTRY PRE-VALIDATION PROGRAM USING RECONSTRUCTED HUMAN TISSUE-BASED METHODS FOR PREDICTING EYE IRRITATION FOR CHEMICALS: MATTEK EPIOCULAR
  (ID ABS: 260 / Poster Section: PO 21/22)
  
  
• CHEMICAL METABOLIZING ACTIVITY OF AN IN VITRO HUMAN EPIDERMAL (EPIDERM™) MODEL AND GENOTOXICITY AS DETERMINED BY IN VITRO SKIN MICRONUCLEUS ASSAYS
  (ID ABS: 457 / Poster Section: PO 21/22)
  
  
• TISSUE ENGINEERED IN VITRO HUMAN AIRWAY MODELS (EPIAIRWAY™) OF ASTHMA AND COPD
  (ID ABS: 458 / Poster Section: PO 26)
  
  
• REGULATORY REQUIREMENTS FOR IN VITRO SYSTEMS TO MEET PERFORMANCE STANDARDS DURING VALIDATION AND OVER TIME
  (ID ABS: 460 / Poster Section: PO 9)
  
  
• DEVELOPMENT OF AN EPIDERM IN VITRO SKIN IRRITATION TEST (SIT) FOR THE GLOBALLY HARMONIZED SYSTEM (GHS) OF CLASSIFICATION AND LABELING OF CHEMICALS
  (ID ABS: 468 / Poster Section: PO 21/22)
  
  
• EPIOCULAR TISSUE MODEL PROTOCOLS FOR 1) REACH OCULAR IRRITATION SCREENING AND 2) ULTRA-MILD EYE CARE COSMETICS
  (ID ABS: 471 / Poster Section: PO 21/22)
  
  
• USE OF THE RECONSTRUCTED EPIVAGINAL TISSUE MODEL TO SCREEN IRRITATION POTENTIAL OF FEMININE HYGIENE PRODUCTS
  (ID ABS: 477 / Poster Section: PO 21/22)
  
  
• A PLASMACYTOID DENDRITIC CELL-BASED ASSAY TO SCREEN THE ALLERGENICITY POTENTIAL OF CHEMICALS
  (ID ABS: 486 / Poster Section: PO 29)
  
  
• THE EPIDERM-FT FULL-THICKNESS IN VITRO HUMAN SKIN MODEL: AN ANIMAL ALTERNATIVE WOUND HEALING MODEL
  (ID ABS: 509 / Poster Section: PO 21/22)
  
  

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Skin Irritation Test Training VIDEO:

ECVAM-Validated EpiDerm SIT Protocol - Training VIDEO Now Available!

To View the VIDEO:
Click on this Link