About MatTek Corporation
MatTek Corporation was founded in 1985 by two chemical engineering professors from MIT. In 1991 the company leveraged its core polymer surface modification technology into the emerging tissue engineering market.
MatTek Corporation is a global industry leader in tissue engineering. The company produces ready-to-use, normal (non-transformed), human cell-derived, fully differentiated, 3-D, organotypic in vitro TISSUE equivalents for use in product development/efficacy, claims substantiation, safety assessment, and target organ research applications.
EpiDerm™, MatTek's first 3D human cell based in vitro model, was introduced in 1993 and became an immediate technical and commercial success. MatTek revolutionized the market for human cell-based in vitro models by:
- Reducing the cost of such models by 50-80%.
- Optimizing researchers' results by introducing published QC standards (concurrent positive and negative controls), assuring a level of reproducibility acceptable to industry and regulators.
- Increasing industry and regulator confidence in the performance of commercially available in vitro tissue models.
The creative use of non-animal (in vitro) testing was fueled by the powerful synergistic effect of lower (direct / indirect) costs and significantly improved product quality. MatTek dramatically reduced product cost and increased lab efficiency by consistently delivering high quality, reproducible, products. In turn, this has led to rapid acceptance and utilization of MatTek's in vitro products by a wide array of major international corporations. The outstanding reproducibility of EpiDerm and EpiOcular, MatTek's corneal tissue model, led directly to impressive results in international multi-laboratory pre-validation and validation studies.
Commercial companies are now empowered to achieve the desirable humane and sociopolitical goals of reducing the number animals used in research while simultaneously controlling costs and generating more relevant, species specific, reproducible data.
MatTek's human cell-derived tissue models are widely used in the United States, Europe and Japan. Commercial companies and academic researchers worldwide employ MatTek's models to explore an extremely wide variety of scientific challenges from apoptosis to zymography. MatTek's models are used for applications as diverse as skin irritation and basic research into cystic fibrosis. An extensive list of technical references by academics and sector companies (pharmaceutical, chemical, cosmetic, household product), which can be searched and sorted by application, keyword, author or organization, documents the broad problem solving capabilities of MatTek's in vitro products.
The current product offering includes EpiDerm™, MelanoDerm™, EpiOcular™, EpiAirway™, EpiDerm-FT™, a full thickness skin model (dermis & epidermis), EpiVaginal™, an ectocervico-vaginal model, and EpiOral™, an oral (buccal) model.
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Over 400 TECHNICAL REFERENCES Indexed by: application, keyword phrase, author and organization