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274. BARRIER FUNCTION COMPARISON BETWEEN IN VITRO SKIN, ORAL (BUCCAL), AND OCULAR TISSUE MODELS - IMPLICATIONS FOR DRUG DELIVERY STUDIES.

Klausner1, M., Kubilus1, J., Song2, Y., Michniak2, B., 1Department of Research and Development, MatTek, Ashland, MA, 2Department of Pharmacology and Physiology, UMDNJ-NJMS, Newark, NJ. Presented at the American Association...[more]

Category: Technical References, EpiDerm, EpiOcular, EpiOral

275. RECONSTRUCTED HUMAN EPIDERMIS EQUIVALENTS.

Roguet1, R., Bracher2, M., Diembeck3, W., Ponec4, M. 1L'Oreal, Life Sciences, Advanced Research Laboratories, Clichy, France, 2Cosmital SA (Research Company of Wella AG, Germany), Marly, Switzerland. 3Beiersdorf AG, Hamburg,...[more]

Category: Technical References, EpiDerm

276. THE USE OF STANDARDIZED HUMAN SKIN MODELS FOR CUTANEOUS PHARMACOTOXICOLOGY STUDIES.

Roguet, R., L'Oreal, Life Sciences, Advanced Research Laboratories, Clichy, France. Skin Pharmacology and Applied Skin Physiology, 15,(Suppl 1),1-3,(2002). Summary: Reconstructed skin and epidermis models are finding...[more]

Category: Technical References, EpiDerm

277. CHARACTERIZATION OF RECONSTRUCTED SKIN MODELS.

Ponec, M., Boelsma, E., Gibbs, S., Mommaas, M., Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands. Skin Pharmacology and Applied Skin Physiology, 15 (Suppl 1), 4-17, (2002). Summary: The...[more]

Category: Technical References, EpiDerm

278. PERMEATION AND SKIN ABSORPTION: REPRODUCIBILITY OF VARIOUS INDUSTRIAL RECONSTRUCTED HUMAN SKIN MODELS.

Lotte, C., Patouillet, C., Zanini, M., Messager, A., Roguet, R., Advanced Research Laboratories, L'Oreal Life Sciences, Aulnay-sous-Bois, France. Skin Pharmacology and Applied Skin Physiology, 15(suppl 1),18-30, (2002)....[more]

Category: Technical References, EpiDerm

279. IMPROVEMENT OF THE EXPERIMENTAL SETUP TO ASSESS CUTANEOUS BIOAVAILABILITY ON HUMAN SKIN MODELS: DYNAMIC PROTOCOL.

Dreher F., Patouillet C., Fouchard F., Zanini M., Messager A., Roguet R., Cottin M., Leclaire J., Benech-Kieffer F. L'Oreal Research, Aulnay-sous-Bois, France. Skin Pharmacology and Applied Skin Physiology, 15, (Suppl 1),...[more]

Category: Technical References, EpiDerm

280. COMPARISON OF CUTANEOUS BIOAVAILABILITY OF COSMETIC PREPARATIONS CONTAINING CAFFEINE OR ALPHA-TOCOPHEROL APPLIED ON HUMAN SKIN MODELS OR HUMAN SKIN EX VIVO AT FINITE DOSES.

Dreher, F., Fouchard, F., Patouillet, C., Andrian, M., Simonnet, J., Benech-Kieffer, F. L'Oreal Research, Aulnay-sous-Bois, France. Skin Pharmacology and Applied Skin Physiology, 15, (Suppl 1), 40-58, (2002). Summary: The...[more]

Category: Technical References, EpiDerm

281. COMPARISON OF ACTIVITIES DEPENDENT ON GLUTATHIONE S-TRANSFERASE AND CYTOCHROME P-450 IA1 IN CULTURED KERATINOCYTES AND RECONSTRUCTED EPIDERMAL MODELS.

Harris, I.R., Siefken, W., Beck-Oldach, K., Brandt, M., Wittern, K.P., Pollet, D., Paul Gerson Unna-Skin Research Center, Beiersdorf AG, Hamburg, Germany. Skin Pharmacology and Apploed Skin Physiology, 15,(Suppl1), 59-67....[more]

Category: Technical References, EpiDerm

282. NAD(P)H:QUINONE REDUCTASE ACTIVITY IN HUMAN EPIDERMAL KERATINOCYTES AND RECONSTRUCTED EPIDERMAL MODELS.

Harris, I.R., Siefken, W., Beck-Oldach, K., Wittern, K.P., Pollet, D. Paul Gerson Unna-Skin Research Center, Beiersdorf AG, Hamburg, Germany. Skin Pharmacology and Applied Skin Physiology, 15,(Suppl1),68-73. Summary:...[more]

Category: Technical References, EpiDerm

283. RECONSTRUCTED SKIN KITS: REPRODUCIBILITY OF CUTANEOUS IRRITANCY TESTING.

C. Faller, M. Bracher. Cosmital SA (Research Company of Wella AG, Germany), Marly, Switzerland. Skin Pharmacology and Applied Skin Physiology 2002;15 (Suppl. 1):74-91. Summary: The aim of this study was to determine the ...[more]

Category: Technical References, EpiDerm

284. JAGGED-1 MEDIATED ACTIVATION OF NOTCH SIGNALING INDUCES COMPLETE MATURATION OF HUMAN KERATINOCYTES THROUGH NF-B AND PPARγ.

Nickoloff, B.J., Qin, J., Chaturvedi, V., Denning, M., Bonish, B., and Miele, L., Department of Pathology, Loyola University Medical Center, Cardinal Bernardin Cancer Center, IL 60153, USA. Cell Death and Differentiation...[more]

Category: Technical References, EpiDerm

285. EVALUATING THE OCULAR IRRITATION POTENTIAL OF 54 TEST ARTICLES USING THE EPIOCULAR™ HUMAN TISSUE CONSTRUCT MODEL (OCL-200).

ME Blazka1, JW Harbell2, M Klausner3, J Merrill2, J Kubilus3, C Kloos1 and DM Bagley1. 1Colgate-Palmolive Co., Piscataway, NJ, USA. 2Institute for In Vitro Sciences, Gaithersburg, MD, USA. 3MatTek Corp., Ashland, MA, USA. ...[more]

Category: Technical References, EpiOcular

286. EPIDERM™ FULL THICKNESS (EPIDERM-FT™), A DERMAL-EPIDERMAL SKIN MODEL WITH A FULLY DEVELOPED BASEMENT MEMBRANE.

Patrick J. Hayden, Joseph Kubilus, Brenda Burnham, George R. Jackson and Mitch Klausner. MatTek Corp., Ashland, MA (USA). The Toxicologist, 72, S1, 158 (2003). Summary: Paracrine signaling between dermal fibroblasts (FB)...[more]

Category: Technical References, EpiDermFT

287. EVALUATION OF MTT METABOLISM AS A MEANINGFUL INDICATOR OF VIABILTY IN HUMAN CORNEAL EPITHELIAL TISSUE MODELS.

Hines, M.D., Gettings, S.D. and Jones, B.C. Avon Products, Inc., Suffern, NY USA. The Toxicologist, 72, S1, 156 (2003). Summary: Cellular viability is routinely measured by the uptake and reduction of tetrazolium salt...[more]

Category: Technical References, EpiOcular

288. USE OF PROTEOMIC TECHNOLOGIES FOR DISCOVERY OF NEW MARKERS OF SKIN IRRITATION IN VITRO.

Fletcher1, S.T., and Baker2, V.A. 1Safety & Environmental Assurance Centre, Unilever, Bedfordshire, U.K. 2CuDoS Cellular Development Systems Ltd, BioCity Nottingham, U.K. The Toxicologist, 72, S1, 13 (2003)....[more]

Category: Technical References, EpiDerm

289. REGULATION OF ANGIOGENESIS FACTORS BY ULTRAVIOLET RADIATION OR HYDROGEN PEROXIDE IN THE EPIDERM IN VITRO SKIN EQUIVALENT.

Last, T.J., Kubilus, J., Klausner, M., Sheasgreen, J. and Hayden, P. MatTek Corp., Ashland, MA. The Toxicologist, 72, S1, 222 (2003). Summary: Vascular endothelial growth factors (VEGF) released by epidermis in response to...[more]

Category: Technical References, EpiDerm

290. COMPARISON OF IN VITRO MODELS OF PERCUTANEOUS ABSORPTION.

Pugh1, G., Raabe2, H., Moyer2, G., Harbell2, J., Bagley1, D. 1Colgate-Palmolive Company, Piscataway, NJ, USA, 2Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA. The Toxicologist, 72, S1, 380 (2003). Summary: As...[more]

Category: Technical References, EpiDerm

291. RECONSTRUCTED HUMAN VAGINAL-ECTOCERVICAL TISSUE MODELS.

Ayehunie1, S., Cannon1, C., Lamore1, S., Bellavance1, K., Kubilus1, J., LaBonte2, J., Pudney3, J., Anderson3, D., Sodroski2, J., and Klausner1, M. 1MatTek Corporation, Ashland, MA, 2Dana Farber Cancer Institute, and 3Brigham ...[more]

Category: Technical References, EpiVaginal

292. HUMAN β-DEFENSIN EXPRESSION IN A NEW BUCCAL EPITHELIAL TISSUE MODEL.

Kubilus1, J., Breyfogle1, B., Sheasgreen1, J., Hayden1, P., Klausner1, M., Dale2, B.A., Kimball2, J.R. 1MatTek Corporation, Ashland, MA. 2University of Washington, Seattle, WA. J. Invest. Dermatol., 121, (1), Abstract...[more]

Category: Technical References, EpiOral

293. EPIDERM™ FULL THICKNESS (EPIDERMFT™), A DERMAL/EPIDERMAL SKIN EQUIVALENT WITH A FULLY DEVELOPED BASEMENT MEMBRANE.

Patrick J. Hayden, Mitch Klausner, Joseph Kubilus, Seyoum Ayehunie, Brenda Burnham, George R. Jackson and John E. Sheasgreen. MatTek Corp., Ashland MA. J. Invest. Dermatol., 121, (1), Abstract #543, (2003). Summary: ...[more]

Category: Technical References, EpiDermFT

294. IN VITRO PERCUTANEOUS ABSORPTION USING THE MATTEK EPI-606X SKIN CONSTRUCT AND HUMAN SKIN.

Klausner1, M., Bagley3, D., Harbell2, J., Kubilus1, J., Moyer2, G., Pugh3, G., Raabe2, H. 1MatTek Corp., 2Institute for In Vitro Sciences, 3Colgate-Palmolive Co. J. Invest. Dermatol., 121, (1), Abstract #574, (2003)....[more]

Category: Technical References, EpiDerm

295. IMPROVED RESPONSIVENESS OF LANGERHANS / DENDRITIC CELLS TO ALLERGENS.

Ayehunie, S., Lamore, S., Lappen, R., Bellavance, K., Hayden, P., Sheasgreen, J., and Klausner, M. MatTek Corp., Ashland, MA. J. Invest. Dermatol., 121, (1), Abstract #886, (2003). Summary: Langerhans cells (LC) are...[more]

Category: Technical References, DendriticCells

296. NOTCH-1 MEDIATED SIGNALING INCREASES IKKα LEVELS - A CRITICAL DETERMINANT CONTROLLING KERATINOCYTE TERMINAL DIFFERENTIATION AND CELL SURVIVAL.

Chaturvedi, V., Qin, J.Z., Denning, M.F., Miele, L., Nickoloff, B. Pathology, Loyola University Chicago, Maywood, IL, USA. J. Invest. Dermatol., 121, (1), Abstract #493, (2003). Summary: Epidermal formation depends on a...[more]

Category: Technical References, EpiDerm

297. EVIDENCE THAT NITRIC OXIDE IS AN UPSTREAM MEDIATOR OF FASL-MEDIATED KERATINOCYTE APOPTOSIS IN TOXIC EPIDERMAL NECROLYSIS.

Viard-Leveugle, I., Saurat, J-H., French, L.E. Dermatology, Geneva University Hospital, Geneva , CH. J. Invest. Dermatol., 121, (1), Abstract #743, (2003). Summary: Toxic epidermal necrolysis (TEN or Lyell's syndrome)...[more]

Category: Technical References, EpiDerm

298. REPRODUCIBILITY OF EPIAIRWAY™, A DIFFERENTIATED AIRWAY TISSUE MODEL FOR PRE-CLINICAL DRUG DEVELOPMENT STUDIES.

Patrick J. Hayden, Mitchell Klausner, Joseph Kubilus, Robert Jackson, Elizabeth J. Roemer1. MatTek Corporation, Ashland, MA 01721, 1State University of New York at Stony Brook, Stony Brook, NY, 11794. Presented at the...[more]

Category: Technical References, EpiAirway

 

 

 

 

 

 

 

 

 

 

 


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