299. ASSESSMENT OF HUMAN SKIN IRRITATION: VALIDATION OF IN VITRO MODELS.

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MatTek Scientific, Marketing Staff. MatTek Corporation, Ashland, MA (USA). May 2003.

Summary:

Please click on this link to view this White Paper's Executive Summary.

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EpiDerm Data Sheet

EpiDerm Specifications

EpiDerm Technical References

Skin Irritation (EpiDerm Application)

Percutaneous Absorption (EpiDerm Application)

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EpiOcular Data Sheet

EpiOcular Specifications

EpiOcular Technical References

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Applications: Corrosion - skin, Cosmetics analysis, Drug absorption - skin, Drug delivery - transdermal, Irritation - eye (ocular), Irritation - skin, Metabolism - skin, Percutaneous absorption/penetration, Phototoxicity, Reproducibility - eye (ocular) tissue model, Reproducibility - skin tissue models, Transdermal permeation/penetration, Validation - in vitro tissue models

Keywords: 3M Corporation, Alternative methods, Alternative toxicological test methods, Animal-based testing, Avon Products, Beiersdorf, Best in vivo to in vitro correlation, Colgate-Palmolive, Cosmetics, Cutaneous irritancy, Cutaneous irritation, Cutaneous toxicity, Dermal corrosion, Draize rabbit eye test, EC DG XII, ECVAM, EpiDerm, EpiOcular, European Union, Human skin irritation, ICCVAM, In vitro skin models, Kimberly-Clark, L'Oreal, Leiden University, Lipid composition, MTT, MTT ET-50 tissue viability assay, MTT assay, Metabolism, Metabolism studies, Ocular irritancy, Percutaneous absorption, Phototoxicity, Product development, Product safety, Reconstructed skin kits, Reduce, Refine, Relevance, Replace, Reproducibility, Skin irritancy, Skin irritation, Sub-draize, Testing and Improvement of Reconstructed Skin Kits in Order to Elaborate European Standards, Tissue architecture, Validation studies, Wella Cosmital, ZEBET

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